ID V4AIU6_LOTGI Unreviewed; 418 AA.
AC V4AIU6;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=FAM86 N-terminal domain-containing protein {ECO:0000259|Pfam:PF14904};
GN ORFNames=LOTGIDRAFT_156652 {ECO:0000313|EMBL:ESP04044.1};
OS Lottia gigantea (Giant owl limpet).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX NCBI_TaxID=225164 {ECO:0000313|EMBL:ESP04044.1, ECO:0000313|Proteomes:UP000030746};
RN [1] {ECO:0000313|EMBL:ESP04044.1, ECO:0000313|Proteomes:UP000030746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. EEF2KMT family. {ECO:0000256|ARBA:ARBA00005511}.
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DR EMBL; KB199905; ESP04044.1; -; Genomic_DNA.
DR RefSeq; XP_009045526.1; XM_009047278.1.
DR AlphaFoldDB; V4AIU6; -.
DR STRING; 225164.V4AIU6; -.
DR EnsemblMetazoa; LotgiT156652; LotgiP156652; LotgiG156652.
DR GeneID; 20237054; -.
DR KEGG; lgi:LOTGIDRAFT_156652; -.
DR CTD; 20237054; -.
DR HOGENOM; CLU_038942_0_1_1; -.
DR OMA; SQYLYVL; -.
DR OrthoDB; 49253at2759; -.
DR Proteomes; UP000030746; Unassembled WGS sequence.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR029426; FAM86_N.
DR InterPro; IPR019410; Methyltransf_16.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR14614; HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN; 1.
DR PANTHER; PTHR14614:SF164; PROTEIN-LYSINE N-METHYLTRANSFERASE EEF2KMT; 1.
DR Pfam; PF14904; FAM86; 1.
DR Pfam; PF10294; Methyltransf_16; 2.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000030746};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 17..105
FT /note="FAM86 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14904"
FT REGION 261..280
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 418 AA; 47744 MW; 60A08860978B8BBE CRC64;
MAASMKKDVS ASNSFHPEEL LRNLSAQFLE MVPVRKIKWE EEQASALVTS QEIQRNVLRA
TVQHPICLIY PPSLSYRRYF MKTLIHKLEE YQADICDEIY EVYTDLLQQS EEEDDTLCYK
TYSLPDGGEV SLQESVNLVC QGTTGLSTWQ AAQHLTEFVL ENKERFENRN ILELGSGLGL
TGIVTCIKCH VNSYTFSDCH PQVLYLLAKN IEANLTQQIP RFQEGSDRDK KIIRKIRRQL
SINAESYAEL VGNEESMIMS PTQSQTLPDQ NDEDEIQSDP NDLELNNKYW ILDKNGLHGT
YKKDDKVRIA KLDWENVDND LMLKLKPDVI LAADVIYDST INPSLVAVLQ MLLKPHPDTG
QIPIVYLAST VRNEDTRDSF LILLGSEGLV YTIVEPPKLS LFYYDRSVPI EILQISTQ
//
