ID V4AM15_LOTGI Unreviewed; 163 AA.
AC V4AM15;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Suppressor of cytokine signaling 7 {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=LOTGIDRAFT_144981 {ECO:0000313|EMBL:ESO94641.1};
OS Lottia gigantea (Giant owl limpet).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX NCBI_TaxID=225164 {ECO:0000313|EMBL:ESO94641.1, ECO:0000313|Proteomes:UP000030746};
RN [1] {ECO:0000313|EMBL:ESO94641.1, ECO:0000313|Proteomes:UP000030746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
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DR EMBL; KB201785; ESO94641.1; -; Genomic_DNA.
DR RefSeq; XP_009054675.1; XM_009056427.1.
DR AlphaFoldDB; V4AM15; -.
DR STRING; 225164.V4AM15; -.
DR EnsemblMetazoa; LotgiT144981; LotgiP144981; LotgiG144981.
DR GeneID; 20234899; -.
DR KEGG; lgi:LOTGIDRAFT_144981; -.
DR CTD; 20234899; -.
DR HOGENOM; CLU_079452_4_2_1; -.
DR OMA; LYDCDWY; -.
DR OrthoDB; 5401079at2759; -.
DR Proteomes; UP000030746; Unassembled WGS sequence.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR036036; SOCS_box-like_dom_sf.
DR PANTHER; PTHR10155; PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR10155:SF5; SUPPRESSOR OF CYTOKINE-SIGNALING 7; 1.
DR Pfam; PF00017; SH2; 1.
DR Pfam; PF07525; SOCS_box; 1.
DR SMART; SM00252; SH2; 1.
DR SMART; SM00253; SOCS; 1.
DR SMART; SM00969; SOCS_box; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR SUPFAM; SSF158235; SOCS box-like; 1.
DR PROSITE; PS50001; SH2; 1.
DR PROSITE; PS50225; SOCS; 1.
PE 4: Predicted;
KW Growth regulation {ECO:0000256|ARBA:ARBA00022604};
KW Reference proteome {ECO:0000313|Proteomes:UP000030746};
KW SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191};
KW Signal transduction inhibitor {ECO:0000256|ARBA:ARBA00022700};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 3..111
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT DOMAIN 106..156
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ESO94641.1"
SQ SEQUENCE 163 AA; 19360 MW; 9D3EC7ED8FFC4E1C CRC64;
CGWYWGPLSY EEAEATLQNK PDGSFLVRDS SNENYILSLS FISHSIVRHT RIEHNKGLFS
FWSQPESHGR VTIKEFIEQT VENSRNGNFH YFLRPPGPGM PPLPIQLVHP ISRFVQFRSL
QHMCRFLILR WVRRDHIDRL PVPEKVKNYL RENQYYVESV EDM
//
