ID V4AMM8_LOTGI Unreviewed; 793 AA.
AC V4AMM8;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=SH3 domain-containing protein {ECO:0000259|PROSITE:PS50002};
DE Flags: Fragment;
GN ORFNames=LOTGIDRAFT_62094 {ECO:0000313|EMBL:ESO98402.1};
OS Lottia gigantea (Giant owl limpet).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX NCBI_TaxID=225164 {ECO:0000313|EMBL:ESO98402.1, ECO:0000313|Proteomes:UP000030746};
RN [1] {ECO:0000313|EMBL:ESO98402.1, ECO:0000313|Proteomes:UP000030746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
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DR EMBL; KB201262; ESO98402.1; -; Genomic_DNA.
DR RefSeq; XP_009050862.1; XM_009052614.1.
DR AlphaFoldDB; V4AMM8; -.
DR STRING; 225164.V4AMM8; -.
DR EnsemblMetazoa; LotgiT62094; LotgiP62094; LotgiG62094.
DR GeneID; 20251645; -.
DR KEGG; lgi:LOTGIDRAFT_62094; -.
DR CTD; 20251645; -.
DR HOGENOM; CLU_007778_0_0_1; -.
DR OMA; IMTQPCD; -.
DR OrthoDB; 49443at2759; -.
DR Proteomes; UP000030746; Unassembled WGS sequence.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR44499; JOUBERIN; 1.
DR PANTHER; PTHR44499:SF1; JOUBERIN; 1.
DR Pfam; PF00018; SH3_1; 1.
DR Pfam; PF00400; WD40; 3.
DR PRINTS; PR00320; GPROTEINBRPT.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 1.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50002; SH3; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000030746};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 342..376
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 383..418
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 430..462
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 735..793
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 626..649
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 12..29
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 628..643
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ESO98402.1"
FT NON_TER 793
FT /evidence="ECO:0000313|EMBL:ESO98402.1"
SQ SEQUENCE 793 AA; 91734 MW; 265CB4876A9F2410 CRC64;
ETPKKMKRKK KKPKEVTEEV SQPEEELSPR EIEDEGKILA VMIHRTDKLK NNFYIQHPLV
RVHIVDQITG HYLVKQHQDR AVTSYYETRA DHLEEILPIM TQPFVFRQQK STLPVWEELL
VFNENFNYFI QDRPQVIVFF ELIDFVSMNK ASRQYEGNKS AGGWHRIAWA FLKIFGGNEE
LNVDKKVRLQ LFEPPNNYKL KTSQVELFQW WQNTIRESYP STLYVTIKGI NSPNMVEPST
RSMFPTQEEL GKMTYEDLQR SMNLTSKTHE ESKRPLTMWN RLHGQTCRIP NHHMMSLKAG
RKGCFVLRFS HDGRSLACAC RDTETYPIII YDIPSGELVG ELTGHFGIVY DLCWSKRDTH
LLSASNDGTA RIWNVKKFLE DHVLPHPTFV YTAQFHPKID SVIVTGAFDQ VIRVWDVEGE
NEDDYLKQEI EDHQGHVNSV CFDEEGEKLY SADSKGVIMV WNTYIDPRRG YITNCTKYQE
IKEPSIKDTP INYMKMHPSG RKLLVHCRDN IIRLFDLRVQ RVIQFYIGSL NFRDKLRSAI
SPCGTFVFAG SEDNIAYVWN TDSGDQVAKY SELNYNQPVT DVEYHPRDHI IALCSIGENQ
PVLLYKYDPN TALLEADEAL VATARTMESP RRTHRKDDPE RQTFSPEPTS ARILTKDQFY
AHEANRYHNV LKKLETVTLG GDPTLFSPHA PPTMSSVMQQ QTFNSQSLYM KDADSSWRPG
FSDIGRNSAP VGRSPPKKMV VAICDYKGQR SDELSVFKGD VIRLLYKDSA NWWMGELANG
QQGYFPANYV AVE
//
