ID   V4ANR5_LOTGI            Unreviewed;      1691 AA.
AC   V4ANR5;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   RecName: Full=RZ-type domain-containing protein {ECO:0000259|PROSITE:PS51981};
GN   ORFNames=LOTGIDRAFT_114003 {ECO:0000313|EMBL:ESO98812.1};
OS   Lottia gigantea (Giant owl limpet).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX   NCBI_TaxID=225164 {ECO:0000313|EMBL:ESO98812.1, ECO:0000313|Proteomes:UP000030746};
RN   [1] {ECO:0000313|EMBL:ESO98812.1, ECO:0000313|Proteomes:UP000030746}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23254933; DOI=10.1038/nature11696;
RA   Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA   Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA   Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA   Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA   Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT   "Insights into bilaterian evolution from three spiralian genomes.";
RL   Nature 493:526-531(2013).
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DR   EMBL; KB201205; ESO98812.1; -; Genomic_DNA.
DR   RefSeq; XP_009050448.1; XM_009052200.1.
DR   STRING; 225164.V4ANR5; -.
DR   EnsemblMetazoa; LotgiT114003; LotgiP114003; LotgiG114003.
DR   GeneID; 20231035; -.
DR   KEGG; lgi:LOTGIDRAFT_114003; -.
DR   CTD; 20231035; -.
DR   HOGENOM; CLU_001066_0_1_1; -.
DR   OMA; CDKKCGQ; -.
DR   OrthoDB; 2971338at2759; -.
DR   Proteomes; UP000030746; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd18808; SF1_C_Upf1; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   InterPro; IPR045055; DNA2/NAM7-like.
DR   InterPro; IPR041679; DNA2/NAM7-like_C.
DR   InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR047187; SF1_C_Upf1.
DR   InterPro; IPR046439; ZF_RZ_dom.
DR   InterPro; IPR000967; Znf_NFX1.
DR   PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR   PANTHER; PTHR10887:SF341; NFX1-TYPE ZINC FINGER-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF13086; AAA_11; 1.
DR   Pfam; PF13087; AAA_12; 1.
DR   Pfam; PF20173; ZnF_RZ-type; 1.
DR   SMART; SM00438; ZnF_NFX; 2.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51981; ZF_RZ; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030746};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          1602..1674
FT                   /note="RZ-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51981"
FT   REGION          107..132
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1691 AA;  194649 MW;  70655EB263DB3F30 CRC64;
     MLQLAVRCFS HACNGDLLST EINFLLSCLL EYSFIYDLIR LESFTQQLVD DCANIVLKLL
     RKFPQECVVK VRPLARVLTE KTETARYLDT NTVENIKTIN NLIDEHTATK TEDASSSRPR
     PHNDDDLPPE DFRELTTIPL ESDLDINKQP FLRKNRLQGR YDNCDQYLDV QFRLLREDLF
     VPLRESISEY QSHCGNTSKT ISSIQVYFNV KLIRPICTNN GLGYTVSFDA KRANNIKWES
     SKRLMYGSLL CLSKDNFQNC VYATVVNRDK KDISNGLLGI RFEFLDIEEL NTFVLENRSH
     RFCMVESPSY YEPYKHVLQG MQHMNEANFP FYNYVVECDT NIQRPAYLKR NSGALYDLRP
     VVDPNFKIKP GTEINFDSEF SSLEYIDIQD DKCWPNPEKL KLDPSQAIAL RQALNREFAI
     IQGPPGTGKT HVGLSILKVL LHNKSIWCPD DNNTPIVIIC YTNHALDQFL LGALDFFDGN
     LVRVGSRSQD DRIKDYAITN HRTRSREGKK VSQAVHNSRV GLKDDMDLLK TEIEESAVKL
     QIAQRDILHE DFLKDEAIIT DEIYVQLKDG KKTSILLKWL GIQQKINEIE RKYHIDAYNI
     GNTTDNVEYD HDDYDEDLPD VWTQVVEREI DDDDDDTLPE LNQLTRSIIS KAQLLDVSSL
     DDISVDFGTA EERKLKVDKR SELRKLKRQL RLNISSDDCM NRMESLNIHN IWKQKYLQRW
     RLYRYWLNLF VEKLSGNIIN REIAYENIAT RYKTVLLAED RDIIKEAGLV GLTTTAAAKY
     HSVLADIGPK IIIFEEAAEV LEGHIVVNLS RHCEHAIFIG DHKQLQPNPT VYKLAKQYNL
     DISLFERLIN NKIPFDTLNK QHRMRPEIAD IVRIVYPALE DHDVVKHYED IKGVENNLAF
     INHSSPDETD EDTKSRANKY EADFIKSLCD YFLKKGYRQD QITILTTYSG QLAYFTDILP
     KTKYSKLRVA TVDSYQGQEN DIILLSLVRS SDEEKIGFLA KENRICVAFS RAKMGFFVIG
     NFEHLQTHST LIKNMVMKAS QKKVLHDGLK IYCLKHHDTR YVSLPSDFRE CLETCGERLK
     CGHACLLPCH SKDEHDDYKC AEQCSRKCNA GHPCNKKCFE KCSPCTYQVM AILPSCGHEQ
     MIACSEEPWM VQCRNNIKKT LPCGHEGEGV CSPNLTSYCN QTTKVTRSKC GHTSEVPCHE
     KDSDLCNFEC EKILDCDHEC SGTCTQCYKG RLHVSCQKPC GRELLCGHIC KDSCTFCPPC
     DDVCINKCQH NRCINKCGEE CIPCKMQCTW QCKHMKCTKR CSEMCDRERC NKPCKKLLPC
     DHFCIGLCGE TCPNLCRLCN REDLEKLNIW GSEDISNSGY IMLEDCKHTL EVTGLDKYMD
     ISDDNSDKQI AFKRCPFCKT HIISTPRYGN LIKTVFNSIY AIKNKIMGNS ENIFKLQQLI
     EDKKRNVNLK VFISSIFDTK NFVQSENHLK AILNQIYIYE KILFMRNQLN RTKAQLQLHD
     DYFGREVQLL IDLERWTSVK RKIFSTQETK DAKLEIKRLW RLVQLCVGRE RANGNSDVPP
     TVIVRLATTI REIHNGRSIP EEDVTELLEI VEEYIPRTTL GITDNERLEI LHAIGGRKGE
     WYQCANGHYY SVGDCSRPLE KSICPECSHE IGGLNHALVG GNIPAPEFDD AEGPVHTEES
     DYLLALELQF G
//