ID V4APZ1_LOTGI Unreviewed; 629 AA.
AC V4APZ1;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Rad21/Rec8-like protein N-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=LOTGIDRAFT_231664 {ECO:0000313|EMBL:ESO96830.1};
OS Lottia gigantea (Giant owl limpet).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX NCBI_TaxID=225164 {ECO:0000313|EMBL:ESO96830.1, ECO:0000313|Proteomes:UP000030746};
RN [1] {ECO:0000313|EMBL:ESO96830.1, ECO:0000313|Proteomes:UP000030746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; KB201362; ESO96830.1; -; Genomic_DNA.
DR RefSeq; XP_009052330.1; XM_009054082.1.
DR AlphaFoldDB; V4APZ1; -.
DR STRING; 225164.V4APZ1; -.
DR EnsemblMetazoa; LotgiT231664; LotgiP231664; LotgiG231664.
DR GeneID; 20248670; -.
DR KEGG; lgi:LOTGIDRAFT_231664; -.
DR CTD; 20248670; -.
DR HOGENOM; CLU_036680_0_0_1; -.
DR OMA; LWRRCAN; -.
DR OrthoDB; 3109352at2759; -.
DR Proteomes; UP000030746; Unassembled WGS sequence.
DR GO; GO:0008278; C:cohesin complex; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
DR CDD; cd21794; Rad21_Rec8_M_Rec8; 1.
DR Gene3D; 1.10.10.580; Structural maintenance of chromosome 1. Chain E; 1.
DR InterPro; IPR039781; Rad21/Rec8-like.
DR InterPro; IPR006909; Rad21/Rec8_C_eu.
DR InterPro; IPR006910; Rad21_Rec8_N.
DR InterPro; IPR023093; ScpA-like_C.
DR PANTHER; PTHR12585:SF75; RAD21_REC8_N DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12585; SCC1 / RAD21 FAMILY MEMBER; 1.
DR Pfam; PF04824; Rad21_Rec8; 1.
DR Pfam; PF04825; Rad21_Rec8_N; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000030746}.
FT DOMAIN 1..114
FT /note="Rad21/Rec8-like protein N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04825"
FT DOMAIN 578..624
FT /note="Rad21/Rec8-like protein C-terminal eukaryotic"
FT /evidence="ECO:0000259|Pfam:PF04824"
FT REGION 240..347
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 413..460
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 278..324
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 413..440
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 629 AA; 71173 MW; CB3295E68B56A8FD CRC64;
MFYSLELLQK RGGQFGIIWV AATEGAKLNK RQITGVRLKK ACNDIIDYIM VRGHHEYGTG
KSRKRFSLYL SSQLMYGVVK IYNRQNDYLL TDATTFMARL RFASSARADI ELRETANSEL
VTLPDPTHIA DPENENFEAT FGRLSNNYQE SLFAHERLRF TSSSSDMDEM LSPIADINIA
PFRPEDIMGS SPHTVSSLDE ITLKQAPLQS HLSTMQTIDE ELLFGLPDII DHVSERLESV
DVPTDQSAEA RPVSPIRPHT PLQTTITEVP IIPVHETPIH RSGEDITREG RDKRKRQKSP
EVTPGHKESR LERRERKRSR QQLVLDEIEM PPPVHKPRRR RRLIIDKDTQ VSKEDFKKNL
QNPNTCLPFV LPDFKAKTFE DYLKQPGRPL CKPLLRLYQR NCKLPRTVVL SESEYSSSTL
TSSSPPTGTS VSSPTTHPET EVLCSPRHFP SSPRHPPAFE LGQASELGQE TSPGKSYSME
RIRLDTSGNI STERAVSFSH SSIDGSLILE QSKLPETSVS RLGEVSVVIE EENLLEDHAE
IPEPAAPFLE SPVETEKQVS PRQFIRELRL STANGQETTF RELVPPESTT RPIAARLFAK
LLEMCKNGQV AARQERPYGD IFITQIEVF
//
