ID V4AYP6_LOTGI Unreviewed; 309 AA.
AC V4AYP6;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 03-MAY-2023, entry version 34.
DE RecName: Full=Transcription initiation factor IIB {ECO:0000256|ARBA:ARBA00013932};
DE AltName: Full=General transcription factor TFIIB {ECO:0000256|ARBA:ARBA00031706};
GN ORFNames=LOTGIDRAFT_238621 {ECO:0000313|EMBL:ESP00286.1};
OS Lottia gigantea (Giant owl limpet).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX NCBI_TaxID=225164 {ECO:0000313|EMBL:ESP00286.1, ECO:0000313|Proteomes:UP000030746};
RN [1] {ECO:0000313|EMBL:ESP00286.1, ECO:0000313|Proteomes:UP000030746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
CC -!- SIMILARITY: Belongs to the TFIIB family.
CC {ECO:0000256|ARBA:ARBA00010857}.
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DR EMBL; KB200786; ESP00286.1; -; Genomic_DNA.
DR RefSeq; XP_009049030.1; XM_009050782.1.
DR AlphaFoldDB; V4AYP6; -.
DR STRING; 225164.V4AYP6; -.
DR EnsemblMetazoa; LotgiT238621; LotgiP238621; LotgiG238621.
DR GeneID; 20250811; -.
DR KEGG; lgi:LOTGIDRAFT_238621; -.
DR CTD; 20250811; -.
DR HOGENOM; CLU_043736_1_1_1; -.
DR OMA; DHDQRMK; -.
DR OrthoDB; 38673at2759; -.
DR Proteomes; UP000030746; Unassembled WGS sequence.
DR GO; GO:0017025; F:TBP-class protein binding; IEA:InterPro.
DR GO; GO:0070897; P:transcription preinitiation complex assembly; IEA:InterPro.
DR CDD; cd20551; CYCLIN_TFIIB_rpt1; 1.
DR CDD; cd20552; CYCLIN_TFIIB_rpt2; 1.
DR Gene3D; 2.20.25.10; -; 1.
DR Gene3D; 1.10.472.10; Cyclin-like; 2.
DR InterPro; IPR013763; Cyclin-like_dom.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR000812; TFIIB.
DR InterPro; IPR023486; TFIIB_CS.
DR InterPro; IPR013150; TFIIB_cyclin.
DR InterPro; IPR013137; Znf_TFIIB.
DR PANTHER; PTHR11618:SF13; TRANSCRIPTION INITIATION FACTOR IIB; 1.
DR PANTHER; PTHR11618; TRANSCRIPTION INITIATION FACTOR IIB-RELATED; 1.
DR Pfam; PF08271; TF_Zn_Ribbon; 1.
DR Pfam; PF00382; TFIIB; 2.
DR PRINTS; PR00685; TIFACTORIIB.
DR SMART; SM00385; CYCLIN; 2.
DR SUPFAM; SSF47954; Cyclin-like; 2.
DR SUPFAM; SSF57783; Zinc beta-ribbon; 1.
DR PROSITE; PS00782; TFIIB; 2.
DR PROSITE; PS51134; ZF_TFIIB; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00469};
KW Reference proteome {ECO:0000313|Proteomes:UP000030746};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00469};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00469}.
FT DOMAIN 9..41
FT /note="TFIIB-type"
FT /evidence="ECO:0000259|PROSITE:PS51134"
SQ SEQUENCE 309 AA; 33691 MW; 38F8BC001E554D04 CRC64;
MASSSRGATV QVNCPEHPDT PLVEDHHAGD MICPECGLVV GDRVIDVGSE WRTFSNDKDA
KDASRVGAAE NSLLDGGDLS TMIAAVPGGE DSGYRNRRTI SSSDRTLISA FKEINQMADR
LNLPKMIADR GSTLFKTVHE GKSLRGRSND AIVSACVYIA CRQEGVPRTF KEICAVSKIS
KKEIGRVFKL IIKNHETNVE LITTGDFMSR FCTNLELPMK VQKAATCIAR KAVDLDLVPG
RSPISVAAAA IYMASQVSNT KKSQKDIGEV AGVAEVTIRQ AYKLMYPKAH VLFPDEFKFD
TPIDQLPLQ
//
