ID   V4B3J4_LOTGI            Unreviewed;       467 AA.
AC   V4B3J4;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   24-JAN-2024, entry version 42.
DE   RecName: Full=PH domain-containing protein {ECO:0000259|PROSITE:PS50003};
GN   ORFNames=LOTGIDRAFT_236877 {ECO:0000313|EMBL:ESO82934.1};
OS   Lottia gigantea (Giant owl limpet).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX   NCBI_TaxID=225164 {ECO:0000313|EMBL:ESO82934.1, ECO:0000313|Proteomes:UP000030746};
RN   [1] {ECO:0000313|EMBL:ESO82934.1, ECO:0000313|Proteomes:UP000030746}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23254933; DOI=10.1038/nature11696;
RA   Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA   Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA   Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA   Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA   Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT   "Insights into bilaterian evolution from three spiralian genomes.";
RL   Nature 493:526-531(2013).
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DR   EMBL; KB203827; ESO82934.1; -; Genomic_DNA.
DR   RefSeq; XP_009066304.1; XM_009068056.1.
DR   AlphaFoldDB; V4B3J4; -.
DR   EnsemblMetazoa; LotgiT236877; LotgiP236877; LotgiG236877.
DR   GeneID; 20250282; -.
DR   KEGG; lgi:LOTGIDRAFT_236877; -.
DR   CTD; 20250282; -.
DR   HOGENOM; CLU_035364_0_0_1; -.
DR   OMA; ANEDMGM; -.
DR   OrthoDB; 4272402at2759; -.
DR   Proteomes; UP000030746; Unassembled WGS sequence.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   PANTHER; PTHR14383:SF1; PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY D MEMBER 1; 1.
DR   PANTHER; PTHR14383; SWAP-70 RECOMBINASE; 1.
DR   Pfam; PF00169; PH; 1.
DR   SMART; SM00233; PH; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030746}.
FT   DOMAIN          1..106
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   REGION          436..467
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          137..363
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        436..460
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   467 AA;  54889 MW;  FC58EB793DC0EFF8 CRC64;
     MAQKLPSNTP LVTNKYIFSR FFMVKDGFLV YYSESEKKEF DKRLHFNVHP KGIIPLGESE
     FKPIQEPGHP FAFQIDSTEL SGKLILAAES DYERKKWLDM LENSRRVTWK NTCLADEMIK
     TLESQGLEMA REKQDYFDRL VSEVNALSEE KMRTEELARV NNELEKEKEK LEKFTTEIRE
     EYDRLKEELD ETTSAMSALD EDNQQLSYLL TEQHNQLESL NGEKENILKK MKNHVKMTSK
     LSIENKEMSE EKNVLNEKLK EIERQQQELM NEKYEAEERI RQNQDMSKHI EEEKIALNEH
     AQELESTIKD LVQQKELTET ELREEIKARL AAETRLKDAE VSLNKLDTAV QSKTAEIDDE
     TKEEMTVNVR KLKQFFEDLA EEAKFAADKP IIVKNAVYAR KTMVRRAQTL KFERRKRSTR
     SQTQVVSMDM KLLMKSDRPI RRSHTSVDSL TRDRLQTKSL PEESIGE
//