ID V4B3Q6_LOTGI Unreviewed; 399 AA.
AC V4B3Q6;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=Apple domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=LOTGIDRAFT_176272 {ECO:0000313|EMBL:ESO83014.1};
OS Lottia gigantea (Giant owl limpet).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX NCBI_TaxID=225164 {ECO:0000313|EMBL:ESO83014.1, ECO:0000313|Proteomes:UP000030746};
RN [1] {ECO:0000313|EMBL:ESO83014.1, ECO:0000313|Proteomes:UP000030746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB203824; ESO83014.1; -; Genomic_DNA.
DR RefSeq; XP_009066298.1; XM_009068050.1.
DR AlphaFoldDB; V4B3Q6; -.
DR EnsemblMetazoa; LotgiT176272; LotgiP176272; LotgiG176272.
DR GeneID; 20243658; -.
DR KEGG; lgi:LOTGIDRAFT_176272; -.
DR CTD; 20243658; -.
DR HOGENOM; CLU_057931_0_0_1; -.
DR Proteomes; UP000030746; Unassembled WGS sequence.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd00033; CCP; 1.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 1.
DR InterPro; IPR003609; Pan_app.
DR InterPro; IPR012314; Pept_M12B_GON-ADAMTSs.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR Pfam; PF08685; GON; 1.
DR Pfam; PF00024; PAN_1; 1.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 1.
DR PROSITE; PS51046; GON; 1.
DR PROSITE; PS50923; SUSHI; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000030746};
KW Signal {ECO:0000256|SAM:SignalP};
KW Sushi {ECO:0000256|PROSITE-ProRule:PRU00302}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..399
FT /note="Apple domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004716620"
FT DOMAIN 130..187
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 187..381
FT /note="GON"
FT /evidence="ECO:0000259|PROSITE:PS51046"
SQ SEQUENCE 399 AA; 44348 MW; 87F0E859E57CCD3A CRC64;
MLLIVVMFAV NSLVAFGGGN QCFQQDDLPN MFKNLEFIHP PFKSVTSLGP IDCARQCKLH
TLCYFVNFNI ETLNCSLISD TGDYSRLNPV SVMIYVKSWN ENILRTCKNH QCPNNTVCKE
NNSGFDCQPI GCTGIPQVPN INVTSFTSKV LWDFNEVVEY ACIRGRFAAT NVTCTSNGFW
SNVDCIQYTK CSNTRICSEM QSKDFWLYLS TFNSRRKVFC SFTGISNAAM YISLPEYNTA
STPIYTRNGT SCELIEATDP STFSMGYTDF KKIRNIISGK IKTTGRMYAN SSFSLQDYGR
AGDCYAGNDS DVCGVIGHFI IDLRGTGFKI NSTAKWKTWG TDGVIQNITW SDDGRVIEGF
CGGNCGGCEP DGELVLEADY TDQPANDSAE LPICKFPLR
//
