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Database: UniProt
Entry: V4B403_LOTGI
LinkDB: V4B403_LOTGI
Original site: V4B403_LOTGI 
ID   V4B403_LOTGI            Unreviewed;       421 AA.
AC   V4B403;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   07-OCT-2020, entry version 33.
DE   RecName: Full=Mitochondria-eating protein {ECO:0000256|ARBA:ARBA00019863};
DE   AltName: Full=Spermatogenesis-associated protein 18 {ECO:0000256|ARBA:ARBA00013974};
GN   ORFNames=LOTGIDRAFT_230554 {ECO:0000313|EMBL:ESP02146.1};
OS   Lottia gigantea (Giant owl limpet).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX   NCBI_TaxID=225164 {ECO:0000313|EMBL:ESP02146.1, ECO:0000313|Proteomes:UP000030746};
RN   [1] {ECO:0000313|EMBL:ESP02146.1, ECO:0000313|Proteomes:UP000030746}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23254933; DOI=10.1038/nature11696;
RA   Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA   Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA   Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA   Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA   Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT   "Insights into bilaterian evolution from three spiralian genomes.";
RL   Nature 493:526-531(2013).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC       Membrane {ECO:0000256|ARBA:ARBA00004370}. Mitochondrion outer membrane
CC       {ECO:0000256|ARBA:ARBA00004294}.
CC   -!- SIMILARITY: Belongs to the MIEAP family.
CC       {ECO:0000256|ARBA:ARBA00008233}.
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DR   EMBL; KB200329; ESP02146.1; -; Genomic_DNA.
DR   RefSeq; XP_009047304.1; XM_009049056.1.
DR   EnsemblMetazoa; LotgiT230554; LotgiP230554; LotgiG230554.
DR   GeneID; 20248331; -.
DR   KEGG; lgi:LOTGIDRAFT_230554; -.
DR   CTD; 20248331; -.
DR   HOGENOM; CLU_652638_0_0_1; -.
DR   OMA; GGMGQLW; -.
DR   OrthoDB; 1198542at2759; -.
DR   Proteomes; UP000030746; Unassembled WGS sequence.
DR   GO; GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR   GO; GO:0035694; P:mitochondrial protein catabolic process; IEA:InterPro.
DR   InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR   InterPro; IPR026169; MIEAP.
DR   InterPro; IPR031981; MIEAP_C.
DR   PANTHER; PTHR21771; PTHR21771; 1.
DR   Pfam; PF10473; CENP-F_leu_zip; 1.
DR   Pfam; PF16026; MIEAP; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030746}.
FT   DOMAIN          114..197
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          217..418
FT                   /note="MIEAP"
FT                   /evidence="ECO:0000259|Pfam:PF16026"
FT   REGION          53..119
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          166..193
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        78..100
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   421 AA;  48289 MW;  6642CCF625B9CFB6 CRC64;
     MSSNATKDLV TEAKNFSSSL ENVFLLKKRD QQSKHLLEKA KALIDGLLVE ATKSSTKKPA
     VPPRPSRTAG GMGQLWVKLD ELKRENEDLR RSRGRSSDER SSPGKVQGPG DVIINDLHKT
     KTENDSLKAK VEKLQKEVKD LQHINATVQD EYKRHKVGFD TAQKSVERVR QDYKSLEVTL
     TNTKKENDTL KQKLTSSVKP IPRTDNRYTE NISERCRPTN IAMRYDTLES QEWMDAKENL
     EDTTGMDEEA ITKFLCDIIM RSYHASQDIY NYLETVIAEL IRRPSLAKSI CENISNGDIA
     ALPDEMTDSL RISLRQICDD LDPFDFVENI KQSLPRDQRS LLSNKAVHRY ISEASRVTWQ
     MILQQPQMTL VADDPQYDDV KHKLWWACDK NSANKVDYYV WPVLYDYDHG NILVKGCVCT
     K
//
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