ID V4BE71_LOTGI Unreviewed; 320 AA.
AC V4BE71;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=PLAT domain-containing protein {ECO:0000259|PROSITE:PS50095};
DE Flags: Fragment;
GN ORFNames=LOTGIDRAFT_109826 {ECO:0000313|EMBL:ESP04057.1};
OS Lottia gigantea (Giant owl limpet).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX NCBI_TaxID=225164 {ECO:0000313|EMBL:ESP04057.1, ECO:0000313|Proteomes:UP000030746};
RN [1] {ECO:0000313|EMBL:ESP04057.1, ECO:0000313|Proteomes:UP000030746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
CC -!- SIMILARITY: Belongs to the polycystin family.
CC {ECO:0000256|ARBA:ARBA00007200}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00152}.
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DR EMBL; KB199905; ESP04057.1; -; Genomic_DNA.
DR RefSeq; XP_009045539.1; XM_009047291.1.
DR AlphaFoldDB; V4BE71; -.
DR STRING; 225164.V4BE71; -.
DR EnsemblMetazoa; LotgiT109826; LotgiP109826; LotgiG109826.
DR GeneID; 20230511; -.
DR KEGG; lgi:LOTGIDRAFT_109826; -.
DR CTD; 20230511; -.
DR HOGENOM; CLU_009624_1_0_1; -.
DR OMA; LITISCM; -.
DR OrthoDB; 2949114at2759; -.
DR Proteomes; UP000030746; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 2.60.220.50; -; 1.
DR Gene3D; 2.60.60.20; PLAT/LH2 domain; 1.
DR InterPro; IPR046338; GAIN_dom_sf.
DR InterPro; IPR000203; GPS.
DR InterPro; IPR001024; PLAT/LH2_dom.
DR InterPro; IPR036392; PLAT/LH2_dom_sf.
DR PANTHER; PTHR10877:SF150; POLYCYSTIC KIDNEY DISEASE AND RECEPTOR FOR EGG JELLY-RELATED PROTEIN; 1.
DR PANTHER; PTHR10877; POLYCYSTIN FAMILY MEMBER; 1.
DR Pfam; PF01825; GPS; 1.
DR Pfam; PF01477; PLAT; 1.
DR SMART; SM00303; GPS; 1.
DR SMART; SM00308; LH2; 1.
DR SUPFAM; SSF49723; Lipase/lipooxygenase domain (PLAT/LH2 domain); 1.
DR PROSITE; PS50221; GPS; 1.
DR PROSITE; PS50095; PLAT; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030746};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 78..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 288..306
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 122..242
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT NON_TER 320
FT /evidence="ECO:0000313|EMBL:ESP04057.1"
SQ SEQUENCE 320 AA; 36301 MW; D9CDFA22FA87755A CRC64;
MANYTFKIVT SDCRFWDVES ESWSTAGCEV SPISNSKFTR CLCNHLTSFA SGVFVPPNQI
NFDTVFDDLG AKLLDNNAVL ITISCMIFVY LVASVWARRK DKQDVEKWGV APLADNVIGD
RYFYQLSVHT GMRGSAGTRS RVSFVLSGDG GDTGVRQLID EKGKKVFNRS SVNQYVMGVP
KGLGPLSYLR IWHDNSGKKK HQGWYLSKVI VTDLQTNQIY FFLCNRWLAV EEDDGMIDRI
LPVAGNSDVT NFNHLFFSQT KKNFTDSHLW ISVFSRPQKS YFTRVQRVGC ILSLVFTTMM
ADAMFYKVSD NMENTMSFEI
//
