ID V4BHF9_LOTGI Unreviewed; 557 AA.
AC V4BHF9;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=MAGUK p55 subfamily member 6 {ECO:0008006|Google:ProtNLM};
GN ORFNames=LOTGIDRAFT_193889 {ECO:0000313|EMBL:ESO88029.1};
OS Lottia gigantea (Giant owl limpet).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX NCBI_TaxID=225164 {ECO:0000313|EMBL:ESO88029.1, ECO:0000313|Proteomes:UP000030746};
RN [1] {ECO:0000313|EMBL:ESO88029.1, ECO:0000313|Proteomes:UP000030746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
CC -!- SIMILARITY: Belongs to the MAGUK family.
CC {ECO:0000256|ARBA:ARBA00007014}.
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DR EMBL; KB202793; ESO88029.1; -; Genomic_DNA.
DR RefSeq; XP_009061342.1; XM_009063094.1.
DR AlphaFoldDB; V4BHF9; -.
DR STRING; 225164.V4BHF9; -.
DR EnsemblMetazoa; LotgiT193889; LotgiP193889; LotgiG193889.
DR GeneID; 20245048; -.
DR KEGG; lgi:LOTGIDRAFT_193889; -.
DR CTD; 20245048; -.
DR HOGENOM; CLU_001715_5_1_1; -.
DR OMA; NPTTPHK; -.
DR OrthoDB; 2873706at2759; -.
DR Proteomes; UP000030746; Unassembled WGS sequence.
DR CDD; cd00071; GMPK; 1.
DR CDD; cd00992; PDZ_signaling; 1.
DR CDD; cd11862; SH3_MPP; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 1.10.287.650; L27 domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR008145; GK/Ca_channel_bsu.
DR InterPro; IPR008144; Guanylate_kin-like_dom.
DR InterPro; IPR020590; Guanylate_kinase_CS.
DR InterPro; IPR014775; L27_C.
DR InterPro; IPR004172; L27_dom.
DR InterPro; IPR036892; L27_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR23122:SF69; FI17352P1; 1.
DR PANTHER; PTHR23122; MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK; 1.
DR Pfam; PF00625; Guanylate_kin; 1.
DR Pfam; PF02828; L27; 1.
DR Pfam; PF00595; PDZ; 1.
DR Pfam; PF07653; SH3_2; 1.
DR SMART; SM00072; GuKc; 1.
DR SMART; SM00569; L27; 2.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF101288; L27 domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS00856; GUANYLATE_KINASE_1; 1.
DR PROSITE; PS50052; GUANYLATE_KINASE_2; 1.
DR PROSITE; PS51022; L27; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000030746};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 64..122
FT /note="L27"
FT /evidence="ECO:0000259|PROSITE:PS51022"
FT DOMAIN 149..228
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 234..303
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 356..542
FT /note="Guanylate kinase-like"
FT /evidence="ECO:0000259|PROSITE:PS50052"
SQ SEQUENCE 557 AA; 63455 MW; 066E78C9B8FE45B6 CRC64;
MPAASRKDIS GTEAVQTIQN NFDALEEREI EAGDEDLDFL RAFLDDPTVV SLFKIHDELE
HGAPEPEASN SVGMARDCLQ IVSSAKDKNR NAASLSKIIQ NPHFKALMVA HDDVVQRDYG
DRVEQEDQTQ SLMSPPPPLF NVITEQVRFV TIRKSDKEPL GITVKLDECN DLVVARILQG
SLIDKQGLLR VNDIIREVNG MPMVTPDQLM ETIVQADNTI TLKIVPSYND SRSTETIYMK
AHFSYDPMKD RLIPCKEAGL PFQDGDILEI VNSDDPNWWQ ARFADIEGPT GLIPSKNLEE
KRKAFVQHDY DNATSICGLT RKKKKKYKYN TKSNTNFDRC DVLIYEEVRR MAPFQRSVLV
LVGANGVGRR SLKERLIRDD PRKFAGVIAH TSRAPRENEE NGRGYYFTDR DSMALDIHDQ
KYIEFGEYNN NLYGTKLETI YDVMKTGKMC VLDVNPTSLK VLKTPEFMPY IVFLAAPSVE
ALKVMYEEGR RLSTTGRGRV KDFIRTVKES AQIEQTYKAY FDLILVNDSF EATYRALRKA
LTSLSSEQQW VPVNWVY
//
