ID   V4BHV7_LOTGI            Unreviewed;       617 AA.
AC   V4BHV7;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   03-MAY-2023, entry version 37.
DE   RecName: Full=HAUS augmin-like complex subunit 3 N-terminal domain-containing protein {ECO:0000259|Pfam:PF14932};
GN   ORFNames=LOTGIDRAFT_228043 {ECO:0000313|EMBL:ESP05467.1};
OS   Lottia gigantea (Giant owl limpet).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX   NCBI_TaxID=225164 {ECO:0000313|EMBL:ESP05467.1, ECO:0000313|Proteomes:UP000030746};
RN   [1] {ECO:0000313|EMBL:ESP05467.1, ECO:0000313|Proteomes:UP000030746}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23254933; DOI=10.1038/nature11696;
RA   Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA   Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA   Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA   Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA   Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT   "Insights into bilaterian evolution from three spiralian genomes.";
RL   Nature 493:526-531(2013).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, spindle
CC       {ECO:0000256|ARBA:ARBA00004186}.
CC   -!- SIMILARITY: Belongs to the HAUS3 family.
CC       {ECO:0000256|ARBA:ARBA00009645}.
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DR   EMBL; KB199650; ESP05467.1; -; Genomic_DNA.
DR   RefSeq; XP_009044012.1; XM_009045764.1.
DR   AlphaFoldDB; V4BHV7; -.
DR   STRING; 225164.V4BHV7; -.
DR   EnsemblMetazoa; LotgiT228043; LotgiP228043; LotgiG228043.
DR   GeneID; 20247514; -.
DR   KEGG; lgi:LOTGIDRAFT_228043; -.
DR   CTD; 20247514; -.
DR   HOGENOM; CLU_442981_0_0_1; -.
DR   OMA; LEWFCGN; -.
DR   OrthoDB; 1110803at2759; -.
DR   Proteomes; UP000030746; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0070652; C:HAUS complex; IEA:InterPro.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0051225; P:spindle assembly; IEA:InterPro.
DR   InterPro; IPR026206; HAUS3.
DR   InterPro; IPR032733; HAUS3_N.
DR   PANTHER; PTHR19378; GOLGIN- RELATED; 1.
DR   PANTHER; PTHR19378:SF0; HAUS AUGMIN-LIKE COMPLEX SUBUNIT 3; 1.
DR   Pfam; PF14932; HAUS-augmin3; 1.
DR   PRINTS; PR02089; HAUSAUGMINL3.
PE   3: Inferred from homology;
KW   Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW   Cell division {ECO:0000256|ARBA:ARBA00022618};
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW   Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW   Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030746}.
FT   DOMAIN          30..284
FT                   /note="HAUS augmin-like complex subunit 3 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14932"
FT   REGION          495..514
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          96..123
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          149..176
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          316..343
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        495..512
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   617 AA;  70477 MW;  03403145B9EA9429 CRC64;
     MKMSGSQFLE TLQQLGYPGA EKLDPQMFDW LFEQENIVPF LHWFSNNVHS NNVLSASDRN
     EYDELEKCNE GILEGRQLED ALNNLTVNNR DADITEESLS EDITRLNSEL EDNKEKKQML
     IQRRNRLSLH HTSVSHKLTK LTPLESYGRK EHKKRLEQIQ TDNNKVNESM EKLVDSVKEV
     TSLYDNTDPS QTKDIMFLSQ AKLDDYFNAE EKYTQELTSF TRKQFFENIG RMTGENDGSR
     FELLDVKDPE MLLIHGESDE NVFQDCKELT RLQNVYNRSE SDKILAILED KGVKGALNSA
     DDLLSCLQSG RFPVDTNKLS TQLQEAQSSL QNVRRDLHNA KEGDLPLLVK ELVPLQGNPI
     LTGDYNLKLA RQDYFTSNQD KLINLLISQK ARYEFLTIAY EVEARHHRDI HRHLTAVRLQ
     LQSHLKEWKN RMDNNGINIT PTNTGFTSPV ATEGISKDYL ESELIKFKSE IKNLFTEVIS
     STVHDVSDRK RKIAADHHNK HGAAHEMSDG ELSEDSVVSN RAVLTQSRFK IPCMDQEQGE
     VEDDDNVIDQ IDNLLNNIDG NSNDEEGLAE DFVNDLFEEY SFDDKSGKEV LPKLAKIIDN
     LFGPAPAASA KAETAMT
//