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Database: UniProt
Entry: V4BQ56_LOTGI
LinkDB: V4BQ56_LOTGI
Original site: V4BQ56_LOTGI 
ID   V4BQ56_LOTGI            Unreviewed;      2890 AA.
AC   V4BQ56;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   16-JAN-2019, entry version 30.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ESO91009.1};
GN   ORFNames=LOTGIDRAFT_163525 {ECO:0000313|EMBL:ESO91009.1};
OS   Lottia gigantea (Giant owl limpet).
OC   Eukaryota; Metazoa; Lophotrochozoa; Mollusca; Gastropoda;
OC   Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX   NCBI_TaxID=225164 {ECO:0000313|EMBL:ESO91009.1, ECO:0000313|Proteomes:UP000030746};
RN   [1] {ECO:0000313|EMBL:ESO91009.1, ECO:0000313|Proteomes:UP000030746}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23254933; DOI=10.1038/nature11696;
RA   Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA   Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA   Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H.,
RA   Aerts A., Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V.,
RA   Lindberg D.R., Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT   "Insights into bilaterian evolution from three spiralian genomes.";
RL   Nature 493:526-531(2013).
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DR   EMBL; KB202284; ESO91009.1; -; Genomic_DNA.
DR   RefSeq; XP_009058280.1; XM_009060032.1.
DR   EnsemblMetazoa; LotgiT163525; LotgiP163525; LotgiG163525.
DR   GeneID; 20239443; -.
DR   KEGG; lgi:LOTGIDRAFT_163525; -.
DR   CTD; 20239443; -.
DR   OMA; HQFANAD; -.
DR   OrthoDB; 94996at2759; -.
DR   Proteomes; UP000030746; Unassembled WGS sequence.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:InterPro.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0070679; F:inositol 1,4,5 trisphosphate binding; IEA:InterPro.
DR   GO; GO:0005220; F:inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; IEA:InterPro.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR000493; InsP3_rcpt.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF01365; RYDR_ITPR; 1.
DR   PRINTS; PR00779; INSP3RECEPTR.
DR   SMART; SM00472; MIR; 3.
DR   SUPFAM; SSF100909; SSF100909; 1.
DR   SUPFAM; SSF82109; SSF82109; 3.
DR   PROSITE; PS50919; MIR; 4.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000030746};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030746};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2225   2245       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2357   2385       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2405   2427       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2474   2501       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      126    180       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      258    322       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      328    403       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      410    464       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   COILED     1002   1022       {ECO:0000256|SAM:Coils}.
FT   COILED     1617   1637       {ECO:0000256|SAM:Coils}.
FT   COILED     2622   2642       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   2890 AA;  331764 MW;  23A030438EED1897 CRC64;
     MGTINSWKEL QNMESLACRT RGLGVFSGLN DRINDKRGYN VDSSSHSGLF IYQNQDRDRP
     SKIPNPHVVV FQVCIQNRYK LNKKYRKWLA LSNGDKPEDK GLLAQAKVAA DAENADNNAE
     QKRQLGKKVR YGEIVQLKHV FTNKYIHMCT SQTSQKDKNN MMIMLQDFNA KNAQFRILPQ
     YKVKSEGEVV QIYDQIVFES IKSPGHYFHG SVPFQIDIST FGSELNLGVE RSGFTLVRYC
     KENPDIDLYV KRGISQIPKY IKGGSVIRLF HKELEAYLVA EGLFDEEVTE DVHFRIRVMD
     QHKPRTLSPP SSGNTFWQIE CENGILNGDV IRWEQQVRLR HMTIRKYLRV DANREITLTD
     DNEDPRTVFR LHSVLSFSLS SDLSRQINLF KDIAENLWIN KINRFSLMER DEIHFESYAR
     IEHVLTGFWL HALKDEDYIR KQFRHIDDTT DQSMRGLRWD TAQVRQVAAS GESMYDDAFT
     IQFVEKQFVD DFNYVSGMVP CLLSLIYDRA EGHILNAKKT HQTLTAMEEL RKFMFVQGLT
     SKNRQKLMRN LRVIDLLVKI LQCPLNGVPD EANLIQVFKE AYDTLYTYMI GKSRKNALYF
     AKYIDFFQTQ FTQKGGIGLN VAQMIVELIR DKRKIVDRIT HSQIDEFVSL LQTSQNYRFL
     DLLHVLCVCD DIAIPNNQSY IVKRWLQCEK KGVYLTARGQ DINRQPNILY LSTSNGQDWM
     ALHEFVDESN PYYNKDQHEF LIHQLDLYKA LSYGRNDYAS NIITKELRYL TWEETFLSLR
     SDILPDAIRA KYCDLTTSLF VDVGNNYSVL DHPNICFVYD YVGSKDEEKS QGDFVIKELV
     AIFPVLRDWI AEFLRDNSFM IACNIGHNML IEQVLRLLYH LVKFGYYLDA EDVRNLLPPL
     LNLLDGRHDY PFPQDKEKGY SKDAMKSVTQ YQLVDRYLVC PETLAIVNAK FQALEVLDLL
     LTYQRNSRLQ SFVGKFKIAE ISTTQKRQNV LTPMLYEQFN PHDQSKKALK KQRQIIKELR
     DMFNSSAIFD VELLTKILMD LSQYKYNKMI TKSLNILNKV YSSKTNMFKL STKAVVLLTQ
     DSARVHREVL KNLPLLRRLA RAKLDDQQVK LMCSILDDMA EFCHLPMTPD EPHPMNQNIL
     ISNGILHILF DILVQDIDIK LFLLARENER VQFYIFERLD VLLEVRVVES DLAIALREVF
     SGNQNTCLKI NPRQIQKVVN RAAELQERGP EFLDLLGMIV KVTGTGLTLK RNQAFVMKYI
     MQNYKKVAFV LDTTQEEREV ILTLTDRVST LRYLLSLLDL LAACAEGENM FIESLCQTIL
     PMEDLLWVLN NPAVENLLKK PFLRCLHHVY MKSNGATVDV STSEIPHDSD LWEYLQSLTT
     ELNKVTDTAK EDPDKLAANL KSPPTKPGGD GFHAADSESS VYGTVLYMLE GCFPFLETFF
     KEFYFPDHST NGNEIEITDQ LAKAILVFSE TTGPLLYKPN HMKNMVNALT VLIPISNLSN
     SSLENVLERF GSGITVEDTS CAIRRGNIEY YADEVDLNTK FRFFAKSAAV VFAGHNSVNA
     QLKLKSKREY TIIGGDEELP LGDEFQSLVK CFVNAHEKKP AKKVESASKL IEQLDISQES
     KRLSETAKQE MDELNIKCLQ VLRAIIHNEE RKLPEDWETR TSEPKIQAQL KIISTIQNFY
     DARGSMNKSL PHLASRNDEI AKEVLAFLCI MLFNANAVVQ SSMLKYFLST REEVFFMAVR
     DRMALSTNSI KEKRSLQAQQ DAKLKDAPTG GKKTVSTFAV SLAALKQIKA YEDALRQQRI
     GGWATKKKPP GKKKKQKKPK EPKKRKEPKK VKKETQANGL KKEVNFTNPL VIKEDQALID
     PPEHELEIAV QIESEPEPEP AQAEETNAAL EYRNDGYIEL VLKVMARMCD GQNKQLQDYL
     REQPDNVKSF DIIAEVTRFL NVVYSNITGK NIDLVIQLFE TMNEFTAGNQ ENRIVIYDNK
     IIDYINFIMR AGDFDNCITD KILELRQSIA NLVMSLIEEN GDGPSQVAME VKDTLDKKAV
     VALMTECYEM HQPDKNRKED MKLAMMAAGG GSTGALSTAK TFAMAGGSFL QGVVKKEKNE
     FAEQYMDVGF SLYLLLNRMH DTDSKLIENI KLQPLQQKAF NFYKKNSMSI EIVKEDDLQK
     INFRVKNKRV LREEVKEKLK WGVNRSSPSN KIRDLMAWTK DIMKDIAYQQ RILSNFIAIC
     LTKGWLFWNH GVTIISFAIN ILMLVTWKAK GSLETPGIMD NATGIPHAII DPVPSIINLG
     QSSYEITIKT LGGAHNFFSL LVLISYFVCN HPRLPDFKSI MTSCKSKFKK KSDDDEIDKK
     KEHQSKLDAQ FFSFTTFYYM VFLALSIGGT FTSGYFFAFH LLNIVNNNQL LSGVIKAVTQ
     NGKSLLWVAV LGLVVFYLYG IIGFALMRSM FDPKDYLYCN TLWQCTITVV RYGLIGDLFE
     VMNPHDNEKT FEKFGVVVLY HVSFFIFITT IGLNIIFGII VDTFSELRDL KWTAESDMRD
     ICFICSRNSY DFEHHGKGFD HHVRYEHNMW AYIFFFIHLN GTKVNDYTAL EMYVYKLLQK
     ENFDFFPLDR ALSLSSMGKD STETKLDDLL YQVTTIVEKQ RVEELEKKRR EERMRQKIWE
     QKHRLGSFRR KARLPGPTEP DPLMQLQGAS GQLDESNRLL QLSPLAQLAQ LGQQVARRAS
     MGGEHRADMG PTLRQHSIAS SHGRHGRGGG GGGSPLRHDS TEQRYFRGSS PSRYDEEPFP
     RNLSPVRYDD RTRSPSRSRH GSEPDLMGLS PVHSRREPSR DYGMLSPKWV ESRATSPRGA
     SIFFPDSDSL SVHSLRDAPP SGQLPDPYLD SIETGPFLID PPEPQRSTSR DTESAESGNS
     GDFTRLETRL
//
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