ID V4BR83_LOTGI Unreviewed; 479 AA.
AC V4BR83;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Lysophospholipid acyltransferase 5 {ECO:0000256|ARBA:ARBA00039721};
DE EC=2.3.1.23 {ECO:0000256|ARBA:ARBA00026120};
DE EC=2.3.1.n6 {ECO:0000256|ARBA:ARBA00038923};
GN ORFNames=LOTGIDRAFT_105367 {ECO:0000313|EMBL:ESO91354.1};
OS Lottia gigantea (Giant owl limpet).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX NCBI_TaxID=225164 {ECO:0000313|EMBL:ESO91354.1, ECO:0000313|Proteomes:UP000030746};
RN [1] {ECO:0000313|EMBL:ESO91354.1, ECO:0000313|Proteomes:UP000030746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
CC -!- PATHWAY: Lipid metabolism; phospholipid metabolism.
CC {ECO:0000256|ARBA:ARBA00005074}.
CC -!- PATHWAY: Phospholipid metabolism. {ECO:0000256|ARBA:ARBA00025707}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the membrane-bound acyltransferase family.
CC {ECO:0000256|ARBA:ARBA00010323}.
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DR EMBL; KB202283; ESO91354.1; -; Genomic_DNA.
DR RefSeq; XP_009058049.1; XM_009059801.1.
DR AlphaFoldDB; V4BR83; -.
DR STRING; 225164.V4BR83; -.
DR EnsemblMetazoa; LotgiT105367; LotgiP105367; LotgiG105367.
DR GeneID; 20229971; -.
DR KEGG; lgi:LOTGIDRAFT_105367; -.
DR CTD; 20229971; -.
DR HOGENOM; CLU_011340_6_0_1; -.
DR OMA; NAWVSRY; -.
DR OrthoDB; 5297955at2759; -.
DR Proteomes; UP000030746; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR InterPro; IPR004299; MBOAT_fam.
DR PANTHER; PTHR13906:SF14; LYSOPHOSPHOLIPID ACYLTRANSFERASE 5; 1.
DR PANTHER; PTHR13906; PORCUPINE; 1.
DR Pfam; PF03062; MBOAT; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030746};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 18..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 50..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 332..350
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 399..421
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 427..449
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 479 AA; 54891 MW; D82B0DAC58B9C355 CRC64;
MSGPVSFLAS SIGTTEDAIR LLLSLLAGYP LSFMYRAYLY HQPNIYKHLY FIVIGLCLAV
FNFGFDVYHS FLNIVLIYVV LLVTPGTKLS VGLAFFINTL YLTLGYIAHS TDTYDFKWTM
PQCVLTLRLT GVVFDVYDGR KKSELSAEQK ETALTKVPSL VELLSLCYCF GGFMIGPQFS
MKRYLDFING AFSHPKTGQA PDSIQPGLKR FCLGTLYIAI YQILGMFVSD DFLLSESFQN
LGFLYKCGYI TVWGKNLLNK YIGSWLLVEG SITILGLSYN GKDKNGNDLW NGCANVRTPE
FEYANTFRDL IHCFNYNTNQ WMAKYIFKRL RFLGNKLISQ GVTLAYLAFW HGLHSGYYNC
FLLEFLMTNM ESQLVSLILK IEIVKTFQSK DYMKPVLWIL RKILITLSMG YALVSFGLLI
TSKYYQIYAG MYFSLHIVFI FWPAVYFILT TYVIPRKKKY VVVPTNDVTT TLQDTPRFV
//
