ID V4C1T4_LOTGI Unreviewed; 259 AA.
AC V4C1T4;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=EGF-like domain-containing protein {ECO:0000259|PROSITE:PS50026};
DE Flags: Fragment;
GN ORFNames=LOTGIDRAFT_117038 {ECO:0000313|EMBL:ESO95414.1};
OS Lottia gigantea (Giant owl limpet).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX NCBI_TaxID=225164 {ECO:0000313|EMBL:ESO95414.1, ECO:0000313|Proteomes:UP000030746};
RN [1] {ECO:0000313|EMBL:ESO95414.1, ECO:0000313|Proteomes:UP000030746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; KB201656; ESO95414.1; -; Genomic_DNA.
DR RefSeq; XP_009053923.1; XM_009055675.1.
DR AlphaFoldDB; V4C1T4; -.
DR STRING; 225164.V4C1T4; -.
DR EnsemblMetazoa; LotgiT117038; LotgiP117038; LotgiG117038.
DR GeneID; 20231440; -.
DR KEGG; lgi:LOTGIDRAFT_117038; -.
DR CTD; 20231440; -.
DR HOGENOM; CLU_004826_12_1_1; -.
DR OMA; VAECVCE; -.
DR OrthoDB; 2900161at2759; -.
DR Proteomes; UP000030746; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 7.
DR Gene3D; 2.10.25.10; Laminin; 7.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR PANTHER; PTHR24049; CRUMBS FAMILY MEMBER; 1.
DR PANTHER; PTHR24049:SF22; DROSOPHILA CRUMBS HOMOLOG; 1.
DR Pfam; PF00008; EGF; 7.
DR PRINTS; PR00010; EGFBLOOD.
DR SMART; SM00181; EGF; 7.
DR SMART; SM00179; EGF_CA; 7.
DR SUPFAM; SSF57196; EGF/Laminin; 4.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 6.
DR PROSITE; PS00022; EGF_1; 7.
DR PROSITE; PS01186; EGF_2; 6.
DR PROSITE; PS50026; EGF_3; 7.
DR PROSITE; PS01187; EGF_CA; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Reference proteome {ECO:0000313|Proteomes:UP000030746};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1..30
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 32..68
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 70..106
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 108..144
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 146..182
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 184..220
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 222..258
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 20..29
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 58..67
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 96..105
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 134..143
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 172..181
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 210..219
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 248..257
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ESO95414.1"
FT NON_TER 259
FT /evidence="ECO:0000313|EMBL:ESO95414.1"
SQ SEQUENCE 259 AA; 27495 MW; A48FC8CFD7FA5BDF CRC64;
NPCTNGGRCV DSDGTYTCEC EPGFTGPQCD VDIDECESSP CVNSGTCISG KNGYTCNCSP
GYTGNRCEFD INECASLPCV HATGCKDLVN DYICYCSPGY AGKNCELEAF ACASTPCKNN
AYCQDIGDSY KCHCPDGTSG KNCENDFDDC QANPCQNAGT CVDEVGGYTC ICIRGYTGDQ
CESPLNQCGN NPCSNKGVCI DLLNRFRCSC PNGFAGRICE INIDECKSNP CQNGGLCVDL
IDDFLCSCPE GFSGITCNE
//
