GenomeNet

Database: UniProt
Entry: V4C734_LOTGI
LinkDB: V4C734_LOTGI
Original site: V4C734_LOTGI 
ID   V4C734_LOTGI            Unreviewed;      1517 AA.
AC   V4C734;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   16-OCT-2019, entry version 31.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ESO97484.1};
GN   ORFNames=LOTGIDRAFT_115014 {ECO:0000313|EMBL:ESO97484.1};
OS   Lottia gigantea (Giant owl limpet).
OC   Eukaryota; Metazoa; Lophotrochozoa; Mollusca; Gastropoda;
OC   Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX   NCBI_TaxID=225164 {ECO:0000313|EMBL:ESO97484.1, ECO:0000313|Proteomes:UP000030746};
RN   [1] {ECO:0000313|EMBL:ESO97484.1, ECO:0000313|Proteomes:UP000030746}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23254933; DOI=10.1038/nature11696;
RA   Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA   Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA   Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H.,
RA   Aerts A., Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V.,
RA   Lindberg D.R., Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT   "Insights into bilaterian evolution from three spiralian genomes.";
RL   Nature 493:526-531(2013).
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DR   EMBL; KB201305; ESO97484.1; -; Genomic_DNA.
DR   RefSeq; XP_009052067.1; XM_009053819.1.
DR   EnsemblMetazoa; LotgiT115014; LotgiP115014; LotgiG115014.
DR   GeneID; 20231167; -.
DR   KEGG; lgi:LOTGIDRAFT_115014; -.
DR   CTD; 20231167; -.
DR   KO; K13709; -.
DR   OMA; HIDKVND; -.
DR   OrthoDB; 110157at2759; -.
DR   Proteomes; UP000030746; Unassembled WGS sequence.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 1.10.10.440; -; 1.
DR   Gene3D; 1.10.555.10; -; 1.
DR   InterPro; IPR002713; FF_domain.
DR   InterPro; IPR036517; FF_domain_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR039007; pG1.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR032835; RhoGAP-FF1.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   InterPro; IPR039006; RhoGAP_pG2.
DR   Pfam; PF01846; FF; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   Pfam; PF16512; RhoGAP-FF1; 1.
DR   SMART; SM00441; FF; 2.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF48350; SSF48350; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS51676; FF; 2.
DR   PROSITE; PS51852; PG1; 1.
DR   PROSITE; PS51853; PG2; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000030746};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030746}.
FT   DOMAIN      398    452       FF. {ECO:0000259|PROSITE:PS51676}.
FT   DOMAIN      454    519       FF. {ECO:0000259|PROSITE:PS51676}.
FT   DOMAIN      562    721       PG1 pseudoGTPase. {ECO:0000259|PROSITE:
FT                                PS51852}.
FT   DOMAIN      733    896       PG2 pseudoGTPase. {ECO:0000259|PROSITE:
FT                                PS51853}.
FT   DOMAIN     1311   1511       Rho-GAP. {ECO:0000259|PROSITE:PS50238}.
FT   REGION      905    986       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION     1031   1050       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION     1116   1219       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION     1232   1307       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COILED      391    411       {ECO:0000256|SAM:Coils}.
FT   COMPBIAS    934    960       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS   1131   1153       Polyampholyte. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS   1160   1203       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS   1245   1262       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS   1271   1302       Polyampholyte. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
SQ   SEQUENCE   1517 AA;  173594 MW;  567C76B9F7247514 CRC64;
     MAKKTEGRSF NVAVIGPSGT DKDKGQCGVG KSFLLNRFLY QVADKYQQEH ISVLSQSDFA
     GRVVNNDHFL YWGEVTKLDD GNNYHFQLIE QTEFIDDVSF QPFKTGRSTD PYYKRCVATK
     VQSLEKLMYI CKEQLGMEND NAYEQKLMPD GKLLIDGFIC CFDVSNVKDR PLEKQVEFVT
     LILNQALKTK KPVVLAATKC DEADERYLRE AERLVARKEF KGSIPIVETS AQENILAVAQ
     EAYRNLLKAH IIDPKASWNL SQKKLGKESD FGHFVDLFGT EVAHKVFKQH TRKLRDEQIR
     AKERKYFSQL PAILSHFLPS LDLVEEKSWS TIQKFVEEHE DFSRYFLHVI EDEEDTWKYH
     DKFIDSNEVR LPFDLLNTPE GDTCYRNQLN ELQVQHRKRE LQKRFKKLLE ENLQVTPGKS
     LGETYVFFVG KECYNGLGDL EKNIVYDEHQ QEIKLKAKQD FQELLWEKSQ VFLGLNSTGR
     LTPDHLKRIN QALQDDPRYK MLQRLEEDRK VMILNHLGFI ECPSKDRCYF KDQCIDNQVQ
     KLLVSYASRP TSTFIESVEE LEGGEKPLNL VLLGKDGVAT ELNREIRKIC TEDEYVYHNT
     TYSLDYRPID GDVSLEHNAL GTANFKPHEQ SLFSDLQREE EATMSSMQIV IIQSYKSSQS
     EKHREILREE GQSLARRLHG EFVEIPDDEV YSDGDIKTFT TKQVHQAIQS VIKQGYNSLG
     GWLMTDQIEP DIRIAMCMMC GDPMPIEIPL GPLLNNENCH VSTNSPNTLN IDAFLDCGKQ
     KIEIEISPNH GGGSLQQGIF HGYILVYSSK RRASLSTLQA LGKRLPPVPK LIVCVADSGG
     ATSFFSSDIS QTLIKEGNAL ADNILYAHFM TTTANFQQQT AVYNPFFKDA WDRKEDSESL
     YIEPLEEPSP PAYERHNYID HRPPAKLPVP YDMYHTTKSS SNSQSTEDSE PIYDQPTHPN
     QYHSDSDRER ASSTSPPPLD DIYSEVADPS VNGEHLVRPS YMNHKAQMNL RILYKPQSSG
     NHKALDYSEH ESQRWDDRNV NGTNGAISVP DTKTRSLQER IVVSHLAKLT SLKLRGHQVC
     APLAIPEPIE IADYGTVKDA VNQYVENDYA SVEDALPPGK LQRIKSSAKK KEKRHTDSDS
     EFSSLERERR PKPYKKSSSK KLHGTSFFMS KSMNDNYQPR LAITTDPDTR GINSPSEGSE
     GTGDELATTR KPVKRKSFKH KGRYTSFGVP KMFSPPIDTE HLNLGSPPML STDDNDYDLN
     DSGNWRSLLK GKTYRDPDKQ RKKEEKKLKD DERKKQKEED SKGSGPSQSG CYIEDFVMSV
     NNPLIPVFIE RCIQFIEEEG MKAEGIYRIP GNKQQVDLLI TKFNENPSAE IGSLDLEIQV
     NAAATVLKGF FSDLTEPLIP PSLYEELIEA AGWLIEGCFC VNDKSSRLLA LRGVLKKLQE
     QNYQVLKYLI THLNRITQNY QYNNMDSGNL AICWWPTLMR LEFKSYENMA LYTRYPVEIL
     MTMIEQCNFM FHEGDEV
//
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