ID V4CL79_LOTGI Unreviewed; 286 AA.
AC V4CL79;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 03-MAY-2023, entry version 34.
DE RecName: Full=Checkpoint protein {ECO:0000256|PIRNR:PIRNR011312};
GN ORFNames=LOTGIDRAFT_185806 {ECO:0000313|EMBL:ESP03030.1};
OS Lottia gigantea (Giant owl limpet).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX NCBI_TaxID=225164 {ECO:0000313|EMBL:ESP03030.1, ECO:0000313|Proteomes:UP000030746};
RN [1] {ECO:0000313|EMBL:ESP03030.1, ECO:0000313|Proteomes:UP000030746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
CC -!- SIMILARITY: Belongs to the HUS1 family. {ECO:0000256|ARBA:ARBA00005563,
CC ECO:0000256|PIRNR:PIRNR011312}.
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DR EMBL; KB200129; ESP03030.1; -; Genomic_DNA.
DR RefSeq; XP_009046500.1; XM_009048252.1.
DR AlphaFoldDB; V4CL79; -.
DR STRING; 225164.V4CL79; -.
DR EnsemblMetazoa; LotgiT185806; LotgiP185806; LotgiG185806.
DR GeneID; 20244671; -.
DR KEGG; lgi:LOTGIDRAFT_185806; -.
DR CTD; 20244671; -.
DR HOGENOM; CLU_035754_1_0_1; -.
DR OMA; VCWMRLE; -.
DR OrthoDB; 5094542at2759; -.
DR Proteomes; UP000030746; Unassembled WGS sequence.
DR GO; GO:0030896; C:checkpoint clamp complex; IEA:InterPro.
DR GO; GO:0005730; C:nucleolus; IEA:InterPro.
DR GO; GO:0000077; P:DNA damage checkpoint signaling; IEA:InterPro.
DR Gene3D; 3.70.10.10; -; 1.
DR InterPro; IPR016580; Cell_cycle_HUS1.
DR InterPro; IPR046938; DNA_clamp_sf.
DR InterPro; IPR007150; Hus1/Mec3.
DR PANTHER; PTHR12900:SF0; CHECKPOINT PROTEIN; 1.
DR PANTHER; PTHR12900; MITOTIC AND DNA DAMAGE CHECKPOINT PROTEIN HUS1; 1.
DR Pfam; PF04005; Hus1; 1.
DR PIRSF; PIRSF011312; Cell_cycle_HUS1; 1.
DR SUPFAM; SSF55979; DNA clamp; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000030746}.
FT REGION 211..231
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 211..228
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 286 AA; 32701 MW; 67824A559EF2B7A1 CRC64;
MKFRGKLVDV GCIQHFTRIV GTVSKMIKTC VLRITIDKLY FILTEQTVSG GVQIWCELPQ
GHFFDEYAME GVSAEDNEIF LELAPENLLR AMKTTQSAKW VKLKLTKKHI PCLTVEGDLP
TIGSHQRLVV HDIPVSVVAR RHWQDYQEPL MPEIDVSIAM PQIRLLRNVI DKMKNLSNYV
VISANKNGEM KLQVETDMVS ISTHFLDLIN PTTRRDSNSQ SSSQSDRDPS EFAEGRIDIR
RFSQFLSSQQ VNPQRVVCNI VENKMVHFYL INEDVSLQYF MPAVAS
//
