ID V4CLT5_LOTGI Unreviewed; 425 AA.
AC V4CLT5;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Major facilitator superfamily (MFS) profile domain-containing protein {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=LOTGIDRAFT_92528 {ECO:0000313|EMBL:ESP03275.1};
OS Lottia gigantea (Giant owl limpet).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX NCBI_TaxID=225164 {ECO:0000313|EMBL:ESP03275.1, ECO:0000313|Proteomes:UP000030746};
RN [1] {ECO:0000313|EMBL:ESP03275.1, ECO:0000313|Proteomes:UP000030746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the unc-93 family.
CC {ECO:0000256|ARBA:ARBA00009172}.
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DR EMBL; KB200071; ESP03275.1; -; Genomic_DNA.
DR RefSeq; XP_009046074.1; XM_009047826.1.
DR AlphaFoldDB; V4CLT5; -.
DR EnsemblMetazoa; LotgiT92528; LotgiP92528; LotgiG92528.
DR GeneID; 20252949; -.
DR KEGG; lgi:LOTGIDRAFT_92528; -.
DR CTD; 20252949; -.
DR HOGENOM; CLU_025356_1_1_1; -.
DR OMA; NTLICIT; -.
DR OrthoDB; 3686389at2759; -.
DR Proteomes; UP000030746; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR010291; Ion_channel_UNC-93.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR19444:SF13; PROTEIN UNC-93 HOMOLOG A; 1.
DR PANTHER; PTHR19444; UNC-93 RELATED; 1.
DR Pfam; PF05978; UNC-93; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030746};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 35..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 63..81
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 131..154
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 252..271
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 286..309
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 316..336
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 405..422
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ESP03275.1"
FT NON_TER 425
FT /evidence="ECO:0000313|EMBL:ESP03275.1"
SQ SEQUENCE 425 AA; 47720 MW; 55727D320EBDB511 CRC64;
KNLIILCTGF ILIFSAFRGI QNLQSSINTS SYLGITTMTC VYLSMFCTCI FAPIVINIFT
AKWALSIGML CFLIWFGANF YPRFYTLIPT ALFAGFGQGI LWSAEISYIL KLAFDSARIT
KDQLENEMFR FHGIFLACFQ TTHIWGNLIS SVLLSHRSEF IPPAVPETSF DYLNYTDPGM
GYEMEGAMEE PPPISAGQLL WKLMCAYIVL GFIGFGLILL LLDKIGARSD PDKTGFQLVV
HHFNQMINHK TFRMLIPLLI FNGVQQGFIF SDFNHYFVTC ALGVEYIGYS MIILGVANVL
SSIMVALCAR YIPREVVLGF GSVMHIALMI GFLIWIPNSQ PMIFFLLSAA WGVCDAVWQT
QCNTLICITC LDDPETAFAN YRMLQSLGLA LAFGSGTFFC VSAKLYFLMT LLVVAIMFYV
LAEYR
//
