ID V4HFR3_9EURY Unreviewed; 610 AA.
AC V4HFR3;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=glycine--tRNA ligase {ECO:0000256|ARBA:ARBA00012829};
DE EC=6.1.1.14 {ECO:0000256|ARBA:ARBA00012829};
GN ORFNames=K933_03225 {ECO:0000313|EMBL:ESP89535.1};
OS Candidatus Halobonum tyrrellensis G22.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Haloferacaceae; Halobonum.
OX NCBI_TaxID=1324957 {ECO:0000313|EMBL:ESP89535.1, ECO:0000313|Proteomes:UP000017840};
RN [1] {ECO:0000313|EMBL:ESP89535.1, ECO:0000313|Proteomes:UP000017840}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=G22 {ECO:0000313|EMBL:ESP89535.1,
RC ECO:0000313|Proteomes:UP000017840};
RX PubMed=24336364;
RA Ugalde J.A., Narasingarao P., Kuo S., Podell S., Allen E.E.;
RT "Draft Genome Sequence of 'Candidatus Halobonum tyrrellensis' Strain G22,
RT Isolated from the Hypersaline Waters of Lake Tyrrell, Australia.";
RL Genome Announc. 1:e01001-13(2013).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.
CC {ECO:0000256|ARBA:ARBA00008226}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESP89535.1}.
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DR EMBL; ASGZ01000008; ESP89535.1; -; Genomic_DNA.
DR AlphaFoldDB; V4HFR3; -.
DR STRING; 1324957.K933_03225; -.
DR PATRIC; fig|1324957.4.peg.655; -.
DR eggNOG; arCOG00405; Archaea.
DR OrthoDB; 6113at2157; -.
DR Proteomes; UP000017840; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004820; F:glycine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0006426; P:glycyl-tRNA aminoacylation; IEA:InterPro.
DR CDD; cd00774; GlyRS-like_core; 1.
DR CDD; cd00858; GlyRS_anticodon; 1.
DR Gene3D; 3.30.40.230; -; 1.
DR Gene3D; 3.40.50.800; Anticodon-binding domain; 1.
DR InterPro; IPR002314; aa-tRNA-synt_IIb.
DR InterPro; IPR006195; aa-tRNA-synth_II.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR004154; Anticodon-bd.
DR InterPro; IPR036621; Anticodon-bd_dom_sf.
DR InterPro; IPR027031; Gly-tRNA_synthase/POLG2.
DR InterPro; IPR033731; GlyRS-like_core.
DR InterPro; IPR002315; tRNA-synt_gly.
DR NCBIfam; TIGR00389; glyS_dimeric; 1.
DR PANTHER; PTHR10745:SF0; GLYCINE--TRNA LIGASE; 1.
DR PANTHER; PTHR10745; GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-2; 1.
DR Pfam; PF03129; HGTP_anticodon; 1.
DR Pfam; PF00587; tRNA-synt_2b; 1.
DR PRINTS; PR01043; TRNASYNTHGLY.
DR SUPFAM; SSF52954; Class II aaRS ABD-related; 1.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE 3: Inferred from homology;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:ESP89535.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000017840}.
FT DOMAIN 22..491
FT /note="Aminoacyl-transfer RNA synthetases class-II family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50862"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 610 AA; 66984 MW; 8DDB5847DF9AB427 CRC64;
MSEQGESDPE AGAPTPAATD RDRSEAITEL AKRRGFFFGA SGAYGGVAGF YTYGPQGASL
KDNLESAWRD RFTVRQGNYE IEAPTVMPEA VFEASGHLDG FDDMLVECPE CGTSHRADHL
IEDATDIEDA EALPIPEVEE LLREHDVRCP TCDAPLSDEP VEEFNLMFET SIGPGSGQAG
YLRPETAQGI FVEFPRLKEY ARNQLPFGVT QIGPAYRNEI SPRKGLIRVR EFTQAELEQF
IDPETDEPPL EEVEDVEVTL YSAEAQADDD GEAYTTTVGE AVEDGTIGSP WVGYYLGVAQ
GWYERVGVDP DRFRYRQHLP GELAHYAADC WDAESEVDGD WIEITGFAYR GDYDLSKHAD
HSGESFTVFK QYDEPRTVER PTVDPDMATL GPEFGGAAGD VAEALETLAE RDPDAFDAEE
VTVEVDGEEH AVATDTANFS VEEVTENGEH VTPHVVEPSF GIDRIVYTLI DHAYETDTVD
DEERTYLALD PELAPTHAAV FPLVSNDDRL LEVADGVVSD LRDAGLSVTY DDSGSIGRRY
RRQDEVGTPF CVTVDRDGVE GDGEPTVTLR DRDTTAQVRL PASALAETLA SLRAGETAFD
AVSEAYERVD
//
