ID   V4HGU7_9EURY            Unreviewed;       432 AA.
AC   V4HGU7;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Malate synthase {ECO:0000313|EMBL:ESP87049.1};
GN   ORFNames=K933_16057 {ECO:0000313|EMBL:ESP87049.1};
OS   Candidatus Halobonum tyrrellensis G22.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC   Haloferacaceae; Halobonum.
OX   NCBI_TaxID=1324957 {ECO:0000313|EMBL:ESP87049.1, ECO:0000313|Proteomes:UP000017840};
RN   [1] {ECO:0000313|EMBL:ESP87049.1, ECO:0000313|Proteomes:UP000017840}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=G22 {ECO:0000313|EMBL:ESP87049.1,
RC   ECO:0000313|Proteomes:UP000017840};
RX   PubMed=24336364;
RA   Ugalde J.A., Narasingarao P., Kuo S., Podell S., Allen E.E.;
RT   "Draft Genome Sequence of 'Candidatus Halobonum tyrrellensis' Strain G22,
RT   Isolated from the Hypersaline Waters of Lake Tyrrell, Australia.";
RL   Genome Announc. 1:e01001-13(2013).
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ESP87049.1}.
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DR   EMBL; ASGZ01000064; ESP87049.1; -; Genomic_DNA.
DR   RefSeq; WP_023395782.1; NZ_ASGZ01000064.1.
DR   AlphaFoldDB; V4HGU7; -.
DR   STRING; 1324957.K933_16057; -.
DR   PATRIC; fig|1324957.4.peg.3261; -.
DR   eggNOG; arCOG00760; Archaea.
DR   OrthoDB; 9170at2157; -.
DR   Proteomes; UP000017840; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   Gene3D; 1.20.58.1560; -; 1.
DR   Gene3D; 3.20.20.60; Phosphoenolpyruvate-binding domains; 1.
DR   InterPro; IPR005000; Aldolase/citrate-lyase_domain.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   InterPro; IPR040442; Pyrv_Kinase-like_dom_sf.
DR   NCBIfam; NF041315; malate_syn_AceB_Halo; 1.
DR   PANTHER; PTHR32308:SF10; CITRATE LYASE SUBUNIT BETA; 1.
DR   PANTHER; PTHR32308; LYASE BETA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G13030)-RELATED; 1.
DR   Pfam; PF03328; HpcH_HpaI; 1.
DR   SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
PE   4: Predicted;
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017840}.
FT   DOMAIN          42..255
FT                   /note="HpcH/HpaI aldolase/citrate lyase"
FT                   /evidence="ECO:0000259|Pfam:PF03328"
SQ   SEQUENCE   432 AA;  48231 MW;  7B158A549EBB4141 CRC64;
     MTERRHDREF VRTFFTSPTA VEGEDDSAKM LRRAADLRGL EAPDVWVPDN EDATAPSMRE
     EGAENVAEVV ADSGADFPGE IHPRVVWHRD DPAARYRGFQ QMLTVADPDR GAVDHIDGFV
     IPEVGDIDDW KKADEALTLV ETEHGLDRGS LAMSVIVESG EAELAMRHLR EEVGKPTNSL
     ERLFLLVDGE VDYTKDMRAT TPTGELPPWP ELRHNTSRGA SAAGLIAVDG PYDDIRDVEG
     YRERMEANRA KGMTGIWSLT PGQVVEANTA PLPPETGRWL LSAGDRRVEL DDRDGAWAYD
     GDRLSLDETG DDYRLRVGGD ERRLDAEQLR EELLGLVEYV PSMSDVVDSM EEFEAARESG
     TGAIAIERAA TLRLDGVDVE ISSDRMWDEA TYQAAMTPIR LFQDVYDHRP DQREELEERY
     GEDVVERATT VG
//