ID V4KIZ1_EUTSA Unreviewed; 765 AA.
AC V4KIZ1;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Terpene cyclase/mutase family member {ECO:0000256|RuleBase:RU362003};
DE EC=5.4.99.- {ECO:0000256|RuleBase:RU362003};
GN ORFNames=EUTSA_v10018165mg {ECO:0000313|EMBL:ESQ27223.1};
OS Eutrema salsugineum (Saltwater cress) (Sisymbrium salsugineum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema.
OX NCBI_TaxID=72664 {ECO:0000313|EMBL:ESQ27223.1, ECO:0000313|Proteomes:UP000030689};
RN [1] {ECO:0000313|EMBL:ESQ27223.1, ECO:0000313|Proteomes:UP000030689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23518688; DOI=10.3389/fpls.2013.00046;
RA Yang R., Jarvis D.E., Chen H., Beilstein M.A., Grimwood J., Jenkins J.,
RA Shu S., Prochnik S., Xin M., Ma C., Schmutz J., Wing R.A.,
RA Mitchell-Olds T., Schumaker K.S., Wang X.;
RT "The Reference Genome of the Halophytic Plant Eutrema salsugineum.";
RL Front. Plant Sci. 4:46-46(2013).
CC -!- SIMILARITY: Belongs to the terpene cyclase/mutase family.
CC {ECO:0000256|ARBA:ARBA00009755, ECO:0000256|RuleBase:RU362003}.
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DR EMBL; KI517953; ESQ27223.1; -; Genomic_DNA.
DR RefSeq; XP_006389937.1; XM_006389875.1.
DR AlphaFoldDB; V4KIZ1; -.
DR STRING; 72664.V4KIZ1; -.
DR EnsemblPlants; ESQ27223; ESQ27223; EUTSA_v10018165mg.
DR GeneID; 18008238; -.
DR Gramene; ESQ27223; ESQ27223; EUTSA_v10018165mg.
DR KEGG; eus:EUTSA_v10018165mg; -.
DR eggNOG; KOG0497; Eukaryota.
DR OMA; WVHIRQV; -.
DR OrthoDB; 608at2759; -.
DR Proteomes; UP000030689; Unassembled WGS sequence.
DR GO; GO:0005811; C:lipid droplet; IEA:InterPro.
DR GO; GO:0042300; F:beta-amyrin synthase activity; IEA:EnsemblPlants.
DR GO; GO:0090438; F:camelliol C synthase activity; IEA:EnsemblPlants.
DR GO; GO:0016104; P:triterpenoid biosynthetic process; IEA:InterPro.
DR CDD; cd02892; SQCY_1; 1.
DR Gene3D; 1.50.10.20; -; 2.
DR InterPro; IPR032696; SQ_cyclase_C.
DR InterPro; IPR032697; SQ_cyclase_N.
DR InterPro; IPR018333; Squalene_cyclase.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR NCBIfam; TIGR01787; squalene_cyclas; 1.
DR PANTHER; PTHR11764:SF58; BETA-AMYRIN SYNTHASE-RELATED; 1.
DR PANTHER; PTHR11764; TERPENE CYCLASE/MUTASE FAMILY MEMBER; 1.
DR Pfam; PF13243; SQHop_cyclase_C; 1.
DR Pfam; PF13249; SQHop_cyclase_N; 1.
DR SFLD; SFLDG01016; Prenyltransferase_Like_2; 1.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 2.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|RuleBase:RU362003};
KW Reference proteome {ECO:0000313|Proteomes:UP000030689};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 103..304
FT /note="Squalene cyclase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13249"
FT DOMAIN 418..756
FT /note="Squalene cyclase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13243"
SQ SEQUENCE 765 AA; 87746 MW; 136D651D8A1E0C9D CRC64;
MWKLKIANGN KEEPYLFSTN NFLGRQTWEF DPDAGTAEER AAVEEARRNF FDDRFRVKAS
SDLIWRMQFL KEKKFEESIP PAPVKVEDAK KITSEAATNA LRRGVNFLSA LQASDGHWPA
ENAGPLFFLP PLVFCLFVTG HLQEIFTKEH LRETLRYIYC HQNEDGGWGL HIEGHSTMFC
TTLNYICVRL LGEGPNGGPG NACERARKWI LSHGGATYIP SWGKTWLSIL GVFDWSGSNP
MPPEFWILPS FLPIHPAKMW CYCRLVYMPM SYLYGKRFVG PTSPLILQLR EEIYLQPYAE
INWNRARHLC AKEDAYYPRP LVQDVIWDCL YIFSEPFLTC WPFNKLLREK ALGVTMKHIH
YEDENSRYIT IGCVEKALCM LACWVEDPNG IYFKKHLLRI SDYLWIAEDG MKMQSFGSQL
WDSGFALQAL VASNLSNEIP DVLRRGYEFL KNSQVRENPS SDFTSMHRHI SKGSWTFSDR
DHGWQASDCT AEGLKCCLLL SMMPPDIIGP KMDPEQLYES VTILLSLQSK NGGVTAWEPA
RGQEWLELLN PTEFFADIVV EHEYNECTSS TIQALVLFKQ LYPKHRTEEI NSSIKKAVQY
IENIQMIDGS WYGSWGVCFT YSTWFGLGGL AAAGKTYNNC LAMRKGVHFL LTTQKDNGGW
GESYLSCSRK RYIPSEGERS NLVQTSWAMM GLLHAGQAER DPTPLHRAAK LLINSQLENG
DFPQQEITGA FMKNCLLHYA AYRNIFPVWA LAEYRRRVPL PYEKP
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