ID   V4KKS5_EUTSA            Unreviewed;       666 AA.
AC   V4KKS5;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=Anoctamin transmembrane domain-containing protein {ECO:0000259|Pfam:PF04547};
GN   ORFNames=EUTSA_v10018233mg {ECO:0000313|EMBL:ESQ27888.1};
OS   Eutrema salsugineum (Saltwater cress) (Sisymbrium salsugineum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema.
OX   NCBI_TaxID=72664 {ECO:0000313|EMBL:ESQ27888.1, ECO:0000313|Proteomes:UP000030689};
RN   [1] {ECO:0000313|EMBL:ESQ27888.1, ECO:0000313|Proteomes:UP000030689}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23518688; DOI=10.3389/fpls.2013.00046;
RA   Yang R., Jarvis D.E., Chen H., Beilstein M.A., Grimwood J., Jenkins J.,
RA   Shu S., Prochnik S., Xin M., Ma C., Schmutz J., Wing R.A.,
RA   Mitchell-Olds T., Schumaker K.S., Wang X.;
RT   "The Reference Genome of the Halophytic Plant Eutrema salsugineum.";
RL   Front. Plant Sci. 4:46-46(2013).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; KI517953; ESQ27888.1; -; Genomic_DNA.
DR   RefSeq; XP_006390602.1; XM_006390540.1.
DR   AlphaFoldDB; V4KKS5; -.
DR   STRING; 72664.V4KKS5; -.
DR   EnsemblPlants; ESQ27888; ESQ27888; EUTSA_v10018233mg.
DR   GeneID; 18009430; -.
DR   Gramene; ESQ27888; ESQ27888; EUTSA_v10018233mg.
DR   KEGG; eus:EUTSA_v10018233mg; -.
DR   eggNOG; KOG2513; Eukaryota.
DR   OMA; YENHRTA; -.
DR   OrthoDB; 534027at2759; -.
DR   Proteomes; UP000030689; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007632; Anoctamin.
DR   InterPro; IPR049452; Anoctamin_TM.
DR   PANTHER; PTHR12308; ANOCTAMIN; 1.
DR   PANTHER; PTHR12308:SF73; INCREASED SODIUM TOLERANCE PROTEIN 2; 1.
DR   Pfam; PF04547; Anoctamin; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030689};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        197..221
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        227..252
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        322..343
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        349..367
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        393..414
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        512..532
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        552..581
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        593..611
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          189..627
FT                   /note="Anoctamin transmembrane"
FT                   /evidence="ECO:0000259|Pfam:PF04547"
SQ   SEQUENCE   666 AA;  77104 MW;  3BBC63784BDA8928 CRC64;
     MNGSNGEERI VHEVAMVVPK RVREEEEEGN CVEVLVTELK KRGMVVDRVV GLADEFLKVA
     APLETLGNAA AELHIRKPTR LGIDLPFEMQ GSEAFIRQPD GTLFSWFERF RCYQHLLYGI
     VNCDGCDVTL KFDGRELCWA AGESLVRTLE SEGIIKQMFP LHDELKRKEL LQTWALNWWN
     FTNQPIDQIY SYFGAKIGVY FSFLGMYTQW LIFPAFLGFM VQMVDFGALQ FLVLPSFFIS
     TILWATLFLQ FWKRKNAALL ARWQINYLVG PSQGYRFLGM EWSSLPFPKE LIKNLGNKIS
     TEKEAYQRYE WFAYRKRFRN DVFIILSIIC LQLPFELAYA HIYEMISSDI IKFILTAIYL
     LIIQYLTRLG GKVSVKLINR EINESVEYRA NSLIYKVFGL YFMQTYIGIF YHVLLHRNFM
     TLRQVLLQRL IISQVFWTLM DGSLPYLKYS YRKFRARKKK KNEGGPSTGK IQIASRVEKE
     YFKPAYSASI GVELEDGLFD DSLELALQFG MIMMFACAFP LAFALAAVSN IMEIRTNALK
     LLVTLRRPLP RAAATIGAWL NIWQFLVVTS ICTNSVLLVC LYDQEGKWKI EPGLAAILIM
     EHILLLLKFG LSRLVPEEPA WVRANRVKNV TQAQDMYCKQ LLRSISGEFA SMTKPEREQQ
     QESKQF
//