ID V4KX80_EUTSA Unreviewed; 508 AA.
AC V4KX80;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE RecName: Full=VHS domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=EUTSA_v10007405mg {ECO:0000313|EMBL:ESQ34662.1};
OS Eutrema salsugineum (Saltwater cress) (Sisymbrium salsugineum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema.
OX NCBI_TaxID=72664 {ECO:0000313|EMBL:ESQ34662.1, ECO:0000313|Proteomes:UP000030689};
RN [1] {ECO:0000313|EMBL:ESQ34662.1, ECO:0000313|Proteomes:UP000030689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23518688; DOI=10.3389/fpls.2013.00046;
RA Yang R., Jarvis D.E., Chen H., Beilstein M.A., Grimwood J., Jenkins J.,
RA Shu S., Prochnik S., Xin M., Ma C., Schmutz J., Wing R.A.,
RA Mitchell-Olds T., Schumaker K.S., Wang X.;
RT "The Reference Genome of the Halophytic Plant Eutrema salsugineum.";
RL Front. Plant Sci. 4:46-46(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the TOM1 family.
CC {ECO:0000256|ARBA:ARBA00007708}.
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DR EMBL; KI517683; ESQ34662.1; -; Genomic_DNA.
DR RefSeq; XP_006416309.1; XM_006416246.1.
DR AlphaFoldDB; V4KX80; -.
DR STRING; 72664.V4KX80; -.
DR EnsemblPlants; ESQ34662; ESQ34662; EUTSA_v10007405mg.
DR GeneID; 18992805; -.
DR Gramene; ESQ34662; ESQ34662; EUTSA_v10007405mg.
DR KEGG; eus:EUTSA_v10007405mg; -.
DR eggNOG; KOG1087; Eukaryota.
DR OMA; NPTAMPG; -.
DR OrthoDB; 472902at2759; -.
DR Proteomes; UP000030689; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR GO; GO:0043328; P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IEA:InterPro.
DR CDD; cd14231; GAT_GGA-like_plant; 1.
DR CDD; cd03561; VHS; 1.
DR Gene3D; 1.20.58.160; -; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR004152; GAT_dom.
DR InterPro; IPR038425; GAT_sf.
DR InterPro; IPR044836; TOL_plant.
DR InterPro; IPR014645; TOM1.
DR InterPro; IPR002014; VHS_dom.
DR PANTHER; PTHR45898; TOM1-LIKE PROTEIN; 1.
DR PANTHER; PTHR45898:SF12; TOM1-LIKE PROTEIN 3; 1.
DR Pfam; PF03127; GAT; 1.
DR Pfam; PF00790; VHS; 1.
DR PIRSF; PIRSF036948; TOM1; 1.
DR SMART; SM00288; VHS; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF89009; GAT-like domain; 1.
DR PROSITE; PS50909; GAT; 1.
DR PROSITE; PS50179; VHS; 1.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000030689};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 12..141
FT /note="VHS"
FT /evidence="ECO:0000259|PROSITE:PS50179"
FT DOMAIN 180..268
FT /note="GAT"
FT /evidence="ECO:0000259|PROSITE:PS50909"
FT REGION 263..508
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 347..375
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 429..463
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 468..487
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 488..508
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 508 AA; 55436 MW; 78E618504AC6EA34 CRC64;
MANNAAACAE RATNDMLIGP DWAINIELCD IINMDPSQAK EAVKVLKKRL GSKNSKVQIL
ALYALETLSK NCGESVYQLI VDRDILPDMV KIVKKKPDLS VREKILSLLD TWQEAFGGSG
GRFPQYYNAY NELRSAGIEF PPRTESSVPF FTPPQSQPII AHATATDEDA AIQASLQSDD
ASALSMEEIQ SAQGSVDILM DMLGALDPSH PEGLKEELIV DLVEQCRTYQ RRVMTLVNTT
SDEELLCQGL ALNDNLQRVL QHHDDKAKGN SVPATASTPI PLVSINHDDD DESDDDFAQL
AHRSKRESAR GSGQGGFNPI LPPPPSTRRP VHVESGAMDF LSGDVYKPQG TSESVKPPST
SHSSNQDSSA PVFDDPTPHS KSPEQALFTK PVNDQSERLP PAPWDEGTRV FPPPMSARTN
RRPEYLKHNN VPQHSSSGSD SSYEDLVGQS RNLSLNPTAS AASAATPPKK DDKPEDILFK
DLVDFAKTRK PSSSSSSSKP NNQNNKPF
//
