ID V4L2K5_EUTSA Unreviewed; 297 AA.
AC V4L2K5;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=MBD domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=EUTSA_v10003457mg {ECO:0000313|EMBL:ESQ44525.1};
OS Eutrema salsugineum (Saltwater cress) (Sisymbrium salsugineum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema.
OX NCBI_TaxID=72664 {ECO:0000313|EMBL:ESQ44525.1, ECO:0000313|Proteomes:UP000030689};
RN [1] {ECO:0000313|EMBL:ESQ44525.1, ECO:0000313|Proteomes:UP000030689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23518688; DOI=10.3389/fpls.2013.00046;
RA Yang R., Jarvis D.E., Chen H., Beilstein M.A., Grimwood J., Jenkins J.,
RA Shu S., Prochnik S., Xin M., Ma C., Schmutz J., Wing R.A.,
RA Mitchell-Olds T., Schumaker K.S., Wang X.;
RT "The Reference Genome of the Halophytic Plant Eutrema salsugineum.";
RL Front. Plant Sci. 4:46-46(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; KI517447; ESQ44525.1; -; Genomic_DNA.
DR RefSeq; XP_006403072.1; XM_006403009.1.
DR AlphaFoldDB; V4L2K5; -.
DR STRING; 72664.V4L2K5; -.
DR EnsemblPlants; ESQ44525; ESQ44525; EUTSA_v10003457mg.
DR GeneID; 18020396; -.
DR Gramene; ESQ44525; ESQ44525; EUTSA_v10003457mg.
DR eggNOG; KOG4161; Eukaryota.
DR OMA; WKPDISC; -.
DR OrthoDB; 1217115at2759; -.
DR Proteomes; UP000030689; Unassembled WGS sequence.
DR GO; GO:0000118; C:histone deacetylase complex; IEA:EnsemblPlants.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0019899; F:enzyme binding; IEA:EnsemblPlants.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd01396; MeCP2_MBD; 1.
DR Gene3D; 3.30.40.100; -; 1.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR InterPro; IPR001739; Methyl_CpG_DNA-bd.
DR InterPro; IPR011124; Znf_CW.
DR PANTHER; PTHR12396:SF0; METHYL-CPG BINDING DOMAIN PROTEIN-LIKE, ISOFORM C; 1.
DR PANTHER; PTHR12396; METHYL-CPG BINDING PROTEIN, MBD; 1.
DR Pfam; PF01429; MBD; 1.
DR Pfam; PF07496; zf-CW; 1.
DR SMART; SM00391; MBD; 1.
DR SUPFAM; SSF54171; DNA-binding domain; 1.
DR PROSITE; PS50982; MBD; 1.
DR PROSITE; PS51050; ZF_CW; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000030689};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 87..146
FT /note="CW-type"
FT /evidence="ECO:0000259|PROSITE:PS51050"
FT DOMAIN 152..226
FT /note="MBD"
FT /evidence="ECO:0000259|PROSITE:PS50982"
FT REGION 23..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 239..258
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 273..297
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 34..54
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 241..258
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 297 AA; 33053 MW; 5C8B9538AC58718D CRC64;
MFSSCSSMSQ PCYGNESNNV MEERKIAPFS SGTDFRAVQP SGGSGSSSPT DDATENQLVL
YVSKGSDTEG EGQPTQSQPS SAYKTPCPSI GAFTVQCASC FKWRLMPSMQ KYEEIREQLL
ENPFFCEAAC EWKPNMSCDV PEDISQDGTR LWAIDKPSIA RPPTGWQRLL RIRGEGGTRF
ADVYYVSPSG KKLRSSVEVQ KYLNDHPQYI REGVKLSQFS FQIPKPLQHD YVRKRPTRLM
ESTDNTNTPV ATGANPLASI SPEDQIALQL RNPTEPGLYE SPLKRTRTSE LPSSCSY
//
