ID V4L3X8_EUTSA Unreviewed; 938 AA.
AC V4L3X8;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=FAD-binding FR-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=EUTSA_v10028400mg {ECO:0000313|EMBL:ESQ38384.1};
OS Eutrema salsugineum (Saltwater cress) (Sisymbrium salsugineum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema.
OX NCBI_TaxID=72664 {ECO:0000313|EMBL:ESQ38384.1, ECO:0000313|Proteomes:UP000030689};
RN [1] {ECO:0000313|EMBL:ESQ38384.1, ECO:0000313|Proteomes:UP000030689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23518688; DOI=10.3389/fpls.2013.00046;
RA Yang R., Jarvis D.E., Chen H., Beilstein M.A., Grimwood J., Jenkins J.,
RA Shu S., Prochnik S., Xin M., Ma C., Schmutz J., Wing R.A.,
RA Mitchell-Olds T., Schumaker K.S., Wang X.;
RT "The Reference Genome of the Halophytic Plant Eutrema salsugineum.";
RL Front. Plant Sci. 4:46-46(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the RBOH (TC 5.B.1.3) family.
CC {ECO:0000256|ARBA:ARBA00007975}.
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DR EMBL; KI517537; ESQ38384.1; -; Genomic_DNA.
DR RefSeq; XP_006396931.1; XM_006396868.1.
DR AlphaFoldDB; V4L3X8; -.
DR STRING; 72664.V4L3X8; -.
DR EnsemblPlants; ESQ38384; ESQ38384; EUTSA_v10028400mg.
DR GeneID; 18014552; -.
DR Gramene; ESQ38384; ESQ38384; EUTSA_v10028400mg.
DR KEGG; eus:EUTSA_v10028400mg; -.
DR eggNOG; KOG0039; Eukaryota.
DR OMA; HSFSCLN; -.
DR OrthoDB; 645817at2759; -.
DR Proteomes; UP000030689; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0050664; F:oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor; IEA:InterPro.
DR GO; GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006970; P:response to osmotic stress; IEA:EnsemblPlants.
DR CDD; cd06186; NOX_Duox_like_FAD_NADP; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 3.40.50.80; Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR000778; Cyt_b245_heavy_chain.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR013112; FAD-bd_8.
DR InterPro; IPR017927; FAD-bd_FR_type.
DR InterPro; IPR013130; Fe3_Rdtase_TM_dom.
DR InterPro; IPR013121; Fe_red_NAD-bd_6.
DR InterPro; IPR039261; FNR_nucleotide-bd.
DR InterPro; IPR013623; NADPH_Ox.
DR InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR PANTHER; PTHR11972; NADPH OXIDASE; 1.
DR PANTHER; PTHR11972:SF150; RESPIRATORY BURST OXIDASE HOMOLOG PROTEIN I-RELATED; 1.
DR Pfam; PF08022; FAD_binding_8; 1.
DR Pfam; PF01794; Ferric_reduct; 1.
DR Pfam; PF08030; NAD_binding_6; 1.
DR Pfam; PF08414; NADPH_Ox; 1.
DR PRINTS; PR00466; GP91PHOX.
DR SFLD; SFLDS00052; Ferric_Reductase_Domain; 1.
DR SFLD; SFLDG01168; Ferric_reductase_subgroup_(FRE; 1.
DR SFLD; SFLDG01169; NADPH_oxidase_subgroup_(NOX); 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF52343; Ferredoxin reductase-like, C-terminal NADP-linked domain; 1.
DR SUPFAM; SSF63380; Riboflavin synthase domain-like; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
DR PROSITE; PS51384; FAD_FR; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW NADP {ECO:0000256|ARBA:ARBA00022857};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Peroxidase {ECO:0000256|ARBA:ARBA00022559};
KW Reference proteome {ECO:0000313|Proteomes:UP000030689};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 372..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 455..473
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 510..530
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 551..572
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 584..601
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 732..749
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 251..286
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 601..726
FT /note="FAD-binding FR-type"
FT /evidence="ECO:0000259|PROSITE:PS51384"
FT REGION 59..89
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 113..132
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 938 AA; 106541 MW; 3618F961C234AC27 CRC64;
MSMSFPDQTH DDRWGSDLDS AGEFTHSFPS LPATYSPASG EELLEVTIEY PTGRLVNINS
VTGTGSDPEI TSSSISDSGS TSRSLGWSAS SERQVVANAK QFSRVLKQKL QRISRRDGGG
YSSRSAPEMV VPHGDKITDP AILCRSLTQR LTKSHRNGSC TQRAIHGLRF ISSKENGIAG
WREVQSKFAN LSKDGHLSRC DFAHCIGMEN KNSKEFAEEL FDALCRRRRL MVDKISLQEL
YEFWYQITDE SFDSRLQIFF NMVNKNGDGR ITENEVKEII ILSASANNLS RLRERAEEYA
ALIMEELSPD GIHSQYIELK DLEMLLLQKD TPHSYSQPYS QTSRALSQNL KDTRWGISRN
LLYSLQDSWK RIWVLTLWLM IMTGLFMWKC AQYKRKDAFH VMGYCLVAAK GAAETLKFNM
ALILLPVCRN TITYLRSTAL SYSVPFDDSI NFHKMISVAI IIAMVLHAAS HLACDFPRIL
SSTEADYKRY LVHYFGVTKP TYLDLVKNPV GITGFIMVTF MIIAFTLASR RCRRNITKLP
KPFDKLTGFN AFWYSHHLLL AVYVLLIIHG VFLYLEEKWY RKTIWMYLAV PVLLYAGERI
LRFFRCRLYT VDICKIVIYP GNVVVLHMSK PTSFDYKSGQ YIFVQCPAVS KFEWHPFSIT
SSPGDDYLSI HIRQLGDWTE GIKKVFSVVC EAPEAGKSGL LRADGPNKTS VPELLIDGPY
GAPAQDHLKY DVLLLVGLGI GATPFISILR DLLNNIVKQQ EQAECLSGSC SNSNISSDHS
FSCLNSQAGN RTPQNRRRTL KTKNAYFYWV TREQGSFDWF REIMNEIADS DIKGVIEMHN
YLTSVYDEGD ARSTLLTMIQ TLNHAKNGVD IFSGTKVRTH FGRPKWKKVL SKISTKHKNT
RIGVFYCGGP SLGKELSTLC HEFNQTGCSR FEFHKEQF
//
