ID V4L5M1_EUTSA Unreviewed; 321 AA.
AC V4L5M1;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Glyoxylate/succinic semialdehyde reductase 2, chloroplastic {ECO:0008006|Google:ProtNLM};
GN ORFNames=EUTSA_v10008217mg {ECO:0000313|EMBL:ESQ35033.1};
OS Eutrema salsugineum (Saltwater cress) (Sisymbrium salsugineum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema.
OX NCBI_TaxID=72664 {ECO:0000313|EMBL:ESQ35033.1, ECO:0000313|Proteomes:UP000030689};
RN [1] {ECO:0000313|EMBL:ESQ35033.1, ECO:0000313|Proteomes:UP000030689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23518688; DOI=10.3389/fpls.2013.00046;
RA Yang R., Jarvis D.E., Chen H., Beilstein M.A., Grimwood J., Jenkins J.,
RA Shu S., Prochnik S., Xin M., Ma C., Schmutz J., Wing R.A.,
RA Mitchell-Olds T., Schumaker K.S., Wang X.;
RT "The Reference Genome of the Halophytic Plant Eutrema salsugineum.";
RL Front. Plant Sci. 4:46-46(2013).
CC -!- SIMILARITY: Belongs to the HIBADH-related family. NP60 subfamily.
CC {ECO:0000256|ARBA:ARBA00007598}.
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DR EMBL; KI517683; ESQ35033.1; -; Genomic_DNA.
DR RefSeq; XP_006416680.1; XM_006416617.1.
DR AlphaFoldDB; V4L5M1; -.
DR STRING; 72664.V4L5M1; -.
DR EnsemblPlants; ESQ35033; ESQ35033; EUTSA_v10008217mg.
DR Gramene; ESQ35033; ESQ35033; EUTSA_v10008217mg.
DR KEGG; eus:EUTSA_v10008217mg; -.
DR eggNOG; KOG0409; Eukaryota.
DR OMA; NALGCEY; -.
DR Proteomes; UP000030689; Unassembled WGS sequence.
DR GO; GO:0009507; C:chloroplast; IEA:EnsemblPlants.
DR GO; GO:0030267; F:glyoxylate reductase (NADP+) activity; IEA:EnsemblPlants.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR029154; HIBADH-like_NADP-bd.
DR InterPro; IPR015815; HIBADH-related.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43580:SF10; GLYOXYLATE_SUCCINIC SEMIALDEHYDE REDUCTASE 2, CHLOROPLASTIC; 1.
DR PANTHER; PTHR43580; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR Pfam; PF14833; NAD_binding_11; 1.
DR Pfam; PF03446; NAD_binding_2; 2.
DR PIRSF; PIRSF000103; HIBADH; 2.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000030689}.
FT DOMAIN 53..76
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 77..190
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 193..312
FT /note="3-hydroxyisobutyrate dehydrogenase-like NAD-binding"
FT /evidence="ECO:0000259|Pfam:PF14833"
FT ACT_SITE 199
FT /evidence="ECO:0000256|PIRSR:PIRSR000103-1"
SQ SEQUENCE 321 AA; 33884 MW; 997850B2386B119D CRC64;
MALCSIFCPS IPVRFRPKPV SLFFSKPLFS LSYRVYSSLQ PTPSTKDELG TVSIGFLGMG
IMGSPMAQNL LKAGYKSSPE EVTAACDLTF AMLADPESAI DVACGKNGAV SGISSGKGYV
DVSTVDAASS MLISKQIKDT GALFLEAPVS GSKKPAEDGQ LIFLTAGDKL LYEKAAPFFD
IMGKSRFYLG EVGNGAAMKL VVNMIMGSMM ASFAEGILLS KKVGLDPNVL VEVVSQGAIN
APMYSLKGPS MIKSVYPTAF PLKHQQKDMR LALGLAETVS QSTPVAAAAN ELYKVAKSYG
FSDEDFSAVI EALKAAKSQE A
//
