ID   V4L945_EUTSA            Unreviewed;       288 AA.
AC   V4L945;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=Ribosomal RNA-processing protein 8 {ECO:0000256|RuleBase:RU365074};
DE            EC=2.1.1.- {ECO:0000256|RuleBase:RU365074};
GN   ORFNames=EUTSA_v10027875mg {ECO:0000313|EMBL:ESQ46935.1};
OS   Eutrema salsugineum (Saltwater cress) (Sisymbrium salsugineum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema.
OX   NCBI_TaxID=72664 {ECO:0000313|EMBL:ESQ46935.1, ECO:0000313|Proteomes:UP000030689};
RN   [1] {ECO:0000313|EMBL:ESQ46935.1, ECO:0000313|Proteomes:UP000030689}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23518688; DOI=10.3389/fpls.2013.00046;
RA   Yang R., Jarvis D.E., Chen H., Beilstein M.A., Grimwood J., Jenkins J.,
RA   Shu S., Prochnik S., Xin M., Ma C., Schmutz J., Wing R.A.,
RA   Mitchell-Olds T., Schumaker K.S., Wang X.;
RT   "The Reference Genome of the Halophytic Plant Eutrema salsugineum.";
RL   Front. Plant Sci. 4:46-46(2013).
CC   -!- FUNCTION: Probable methyltransferase required to silence rDNA.
CC       {ECO:0000256|RuleBase:RU365074}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000256|ARBA:ARBA00004604, ECO:0000256|RuleBase:RU365074}.
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily. RRP8 family.
CC       {ECO:0000256|ARBA:ARBA00006301, ECO:0000256|RuleBase:RU365074}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KI517416; ESQ46935.1; -; Genomic_DNA.
DR   RefSeq; XP_006405482.1; XM_006405419.1.
DR   AlphaFoldDB; V4L945; -.
DR   STRING; 72664.V4L945; -.
DR   EnsemblPlants; ESQ46935; ESQ46935; EUTSA_v10027875mg.
DR   GeneID; 18023024; -.
DR   Gramene; ESQ46935; ESQ46935; EUTSA_v10027875mg.
DR   KEGG; eus:EUTSA_v10027875mg; -.
DR   eggNOG; KOG3045; Eukaryota.
DR   OMA; KWPTNPL; -.
DR   OrthoDB; 1694at2759; -.
DR   Proteomes; UP000030689; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-UniRule.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 1.10.10.2150; Ribosomal RNA-processing protein 8, N-terminal domain; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR007823; RRP8.
DR   InterPro; IPR042036; RRP8_N.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR12787:SF0; RIBOSOMAL RNA-PROCESSING PROTEIN 8; 1.
DR   PANTHER; PTHR12787; UNCHARACTERIZED; 1.
DR   Pfam; PF05148; Methyltransf_8; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   3: Inferred from homology;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW   ECO:0000256|RuleBase:RU365074};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU365074};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030689};
KW   rRNA processing {ECO:0000256|ARBA:ARBA00022552,
KW   ECO:0000256|RuleBase:RU365074};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW   ECO:0000256|RuleBase:RU365074};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU365074}.
FT   REGION          1..64
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        18..48
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   288 AA;  32989 MW;  A562B4B02E348A6C CRC64;
     MKEEATSRNR KRKRQRNPKT PKEEPNETPK KQNNDKKNQR ETKTHKNHQH GGSSASSKRP
     KPSNYLDMLR EKLSGGNFRR LNEKLYTCSG QEALDYFRED PDLFDMYHTG YQQQMSNWPE
     LPVNSIINWL LSRSCSLVVA DFGCGDAKIA KSVKNKVFSF DLVAKNPSVI ACDMSNTSLE
     SSSVDVAVFC LSLMGTNYSS YIKEAHRVLR PSGWLLIAEV KSRFDPNNGG ADPKDFVKAV
     CDLGFTSTLK DFSNKMFILL HFKKKEESNS NEKKIEWPEL KACLYKRR
//