ID V4LGH3_EUTSA Unreviewed; 304 AA.
AC V4LGH3;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=cysteine dioxygenase {ECO:0000256|ARBA:ARBA00013133};
DE EC=1.13.11.20 {ECO:0000256|ARBA:ARBA00013133};
GN ORFNames=EUTSA_v10014207mg {ECO:0000313|EMBL:ESQ41482.1};
OS Eutrema salsugineum (Saltwater cress) (Sisymbrium salsugineum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema.
OX NCBI_TaxID=72664 {ECO:0000313|EMBL:ESQ41482.1, ECO:0000313|Proteomes:UP000030689};
RN [1] {ECO:0000313|EMBL:ESQ41482.1, ECO:0000313|Proteomes:UP000030689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23518688; DOI=10.3389/fpls.2013.00046;
RA Yang R., Jarvis D.E., Chen H., Beilstein M.A., Grimwood J., Jenkins J.,
RA Shu S., Prochnik S., Xin M., Ma C., Schmutz J., Wing R.A.,
RA Mitchell-Olds T., Schumaker K.S., Wang X.;
RT "The Reference Genome of the Halophytic Plant Eutrema salsugineum.";
RL Front. Plant Sci. 4:46-46(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-cysteine + O2 = 3-sulfino-L-alanine + H(+);
CC Xref=Rhea:RHEA:20441, ChEBI:CHEBI:15378, ChEBI:CHEBI:15379,
CC ChEBI:CHEBI:35235, ChEBI:CHEBI:61085; EC=1.13.11.20;
CC Evidence={ECO:0000256|ARBA:ARBA00024284};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:20442;
CC Evidence={ECO:0000256|ARBA:ARBA00024284};
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000256|ARBA:ARBA00001954};
CC -!- SIMILARITY: Belongs to the cysteine dioxygenase family.
CC {ECO:0000256|ARBA:ARBA00006622}.
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DR EMBL; KI517464; ESQ41482.1; -; Genomic_DNA.
DR RefSeq; XP_006400029.1; XM_006399966.1.
DR AlphaFoldDB; V4LGH3; -.
DR STRING; 72664.V4LGH3; -.
DR EnsemblPlants; ESQ41482; ESQ41482; EUTSA_v10014207mg.
DR GeneID; 18017957; -.
DR Gramene; ESQ41482; ESQ41482; EUTSA_v10014207mg.
DR KEGG; eus:EUTSA_v10014207mg; -.
DR eggNOG; KOG4281; Eukaryota.
DR OMA; ERECHAW; -.
DR OrthoDB; 5487415at2759; -.
DR Proteomes; UP000030689; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:EnsemblPlants.
DR GO; GO:0005634; C:nucleus; IEA:EnsemblPlants.
DR GO; GO:0017172; F:cysteine dioxygenase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0009061; P:anaerobic respiration; IEA:EnsemblPlants.
DR GO; GO:0070483; P:detection of hypoxia; IEA:EnsemblPlants.
DR CDD; cd20289; cupin_ADO; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR012864; PCO/ADO.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR InterPro; IPR011051; RmlC_Cupin_sf.
DR PANTHER; PTHR22966:SF73; PLANT CYSTEINE OXIDASE 1; 1.
DR PANTHER; PTHR22966; UNCHARACTERIZED; 1.
DR Pfam; PF07847; PCO_ADO; 1.
DR SUPFAM; SSF51182; RmlC-like cupins; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000030689}.
FT REGION 19..62
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..36
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 37..52
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 304 AA; 34143 MW; BA04EE431EA01572 CRC64;
MGFEMKAEKD VLELISSKNQ CKAKNSNPNS VNSPHNNKKK NIRKKSKKMM MTWRRKKTDS
SPEDEITAVR RLFNTCKEVF SDGGPGIVPS EDKIQQLRQI LDNMKPEDVG LTPTMPYFRP
NAGLGNGSSP PITYLHLHQC DQFSIGIFCL PPSGVIPLHN HPGMTVFSKL LFGTMHIKSY
DWVVDAPMKD PKTRLAKVKM DSTLNAPCNA SILYPEDGGN MHRFTAKTAC AVLDVLGPPY
CNPEGRHCTY FLDFPIEIFS SEEDDVLRGE MGKESHAWLQ ERDDNPEDLN VVGALYRGPK
VDED
//
