ID V4LLT9_EUTSA Unreviewed; 627 AA.
AC V4LLT9;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=anthranilate synthase {ECO:0000256|ARBA:ARBA00012266};
DE EC=4.1.3.27 {ECO:0000256|ARBA:ARBA00012266};
GN ORFNames=EUTSA_v10016377mg {ECO:0000313|EMBL:ESQ51485.1};
OS Eutrema salsugineum (Saltwater cress) (Sisymbrium salsugineum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema.
OX NCBI_TaxID=72664 {ECO:0000313|EMBL:ESQ51485.1, ECO:0000313|Proteomes:UP000030689};
RN [1] {ECO:0000313|EMBL:ESQ51485.1, ECO:0000313|Proteomes:UP000030689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23518688; DOI=10.3389/fpls.2013.00046;
RA Yang R., Jarvis D.E., Chen H., Beilstein M.A., Grimwood J., Jenkins J.,
RA Shu S., Prochnik S., Xin M., Ma C., Schmutz J., Wing R.A.,
RA Mitchell-Olds T., Schumaker K.S., Wang X.;
RT "The Reference Genome of the Halophytic Plant Eutrema salsugineum.";
RL Front. Plant Sci. 4:46-46(2013).
CC -!- PATHWAY: Amino-acid biosynthesis; L-tryptophan biosynthesis; L-
CC tryptophan from chorismate: step 1/5. {ECO:0000256|ARBA:ARBA00004873}.
CC -!- SUBUNIT: Heterotetramer consisting of two non-identical subunits: a
CC beta subunit and a large alpha subunit.
CC {ECO:0000256|ARBA:ARBA00011653}.
CC -!- SIMILARITY: Belongs to the anthranilate synthase component I family.
CC {ECO:0000256|ARBA:ARBA00009562}.
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DR EMBL; KI517385; ESQ51485.1; -; Genomic_DNA.
DR RefSeq; XP_006410032.1; XM_006409969.1.
DR AlphaFoldDB; V4LLT9; -.
DR STRING; 72664.V4LLT9; -.
DR EnsemblPlants; ESQ51485; ESQ51485; EUTSA_v10016377mg.
DR GeneID; 18027778; -.
DR Gramene; ESQ51485; ESQ51485; EUTSA_v10016377mg.
DR KEGG; eus:EUTSA_v10016377mg; -.
DR eggNOG; KOG1223; Eukaryota.
DR OMA; TPKEDSM; -.
DR OrthoDB; 705at2759; -.
DR UniPathway; UPA00035; UER00040.
DR Proteomes; UP000030689; Unassembled WGS sequence.
DR GO; GO:0004049; F:anthranilate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0000162; P:tryptophan biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.60.120.10; Anthranilate synthase; 1.
DR InterPro; IPR005801; ADC_synthase.
DR InterPro; IPR019999; Anth_synth_I-like.
DR InterPro; IPR006805; Anth_synth_I_N.
DR InterPro; IPR005256; Anth_synth_I_PabB.
DR InterPro; IPR015890; Chorismate_C.
DR NCBIfam; TIGR00564; trpE_most; 1.
DR PANTHER; PTHR11236; AMINOBENZOATE/ANTHRANILATE SYNTHASE; 1.
DR PANTHER; PTHR11236:SF9; ANTHRANILATE SYNTHASE COMPONENT 1; 1.
DR Pfam; PF04715; Anth_synt_I_N; 1.
DR Pfam; PF00425; Chorismate_bind; 1.
DR PRINTS; PR00095; ANTSNTHASEI.
DR SUPFAM; SSF56322; ADC synthase; 1.
PE 3: Inferred from homology;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Aromatic amino acid biosynthesis {ECO:0000256|ARBA:ARBA00023141};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Reference proteome {ECO:0000313|Proteomes:UP000030689};
KW Tryptophan biosynthesis {ECO:0000256|ARBA:ARBA00022822}.
FT DOMAIN 110..264
FT /note="Anthranilate synthase component I N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04715"
FT DOMAIN 325..596
FT /note="Chorismate-utilising enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00425"
SQ SEQUENCE 627 AA; 69976 MW; 3A0C1B667445A3BC CRC64;
MSAVSNFSVK SDFSVAEAVA VTHHRPPPPP SFPSLRFPSS LASPPATSLH FDGGASISRS
NLLPVSRLRP IKCSSSPTPS LDLLGDQLIK FKEAAEKGNL VPVYRCVFSD HLTPILAYRC
LVKEDDRDAP SFLFESVEPG LQASNIGRYS VVGAQPTIEI VAKGNVVTVM DHGAGLRTEE
EVEDPMMVPQ KIMEEWKPQR IDELPEAFCG GWVGYFSYDT VRYVEKKKLP FSNAPEDDRS
LPDVHLGLYD DVIVFDHVEK KAYVIHWVRI DRDRSVEDNF SDGMNRLESL TSRIQDQKPP
KMPTGFIKLR TELFGPKLEK STMTREAYKE AVLEAKEHIL AGDIFQIVLS QRFERRTFAD
PFEIYRALRI VNPSPYMAYL QARGCILVAS SPEILLRSKN RKITNRPLAG TVRRGKTPKE
DLMLEKELLS DEKQCAEHVM LVDLGRNDVG KVSKPGSVEV EKLMNIERYS HVMHISSTVK
GELLDDLTSW DALRAALPVG TVSGAPKVKA MELIDELEVT RRGPYSGGFG GISFNGDMDI
ALALRTMVFP TNTRYDTLYS YKHPQRRREW IAHIQAGAGV VADSNPDDEQ KECENKAAAL
ARAIDLAESS FLETPEVTTS TPRVNNV
//
