ID V4LRD9_EUTSA Unreviewed; 704 AA.
AC V4LRD9;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=CSC1/OSCA1-like 7TM region domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=EUTSA_v10010925mg {ECO:0000313|EMBL:ESQ45017.1};
OS Eutrema salsugineum (Saltwater cress) (Sisymbrium salsugineum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema.
OX NCBI_TaxID=72664 {ECO:0000313|EMBL:ESQ45017.1, ECO:0000313|Proteomes:UP000030689};
RN [1] {ECO:0000313|EMBL:ESQ45017.1, ECO:0000313|Proteomes:UP000030689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23518688; DOI=10.3389/fpls.2013.00046;
RA Yang R., Jarvis D.E., Chen H., Beilstein M.A., Grimwood J., Jenkins J.,
RA Shu S., Prochnik S., Xin M., Ma C., Schmutz J., Wing R.A.,
RA Mitchell-Olds T., Schumaker K.S., Wang X.;
RT "The Reference Genome of the Halophytic Plant Eutrema salsugineum.";
RL Front. Plant Sci. 4:46-46(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
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DR EMBL; KI517435; ESQ45017.1; -; Genomic_DNA.
DR RefSeq; XP_006403564.1; XM_006403501.1.
DR AlphaFoldDB; V4LRD9; -.
DR STRING; 72664.V4LRD9; -.
DR EnsemblPlants; ESQ45017; ESQ45017; EUTSA_v10010925mg.
DR GeneID; 18021216; -.
DR Gramene; ESQ45017; ESQ45017; EUTSA_v10010925mg.
DR KEGG; eus:EUTSA_v10010925mg; -.
DR eggNOG; KOG1134; Eukaryota.
DR OMA; AYKPPWM; -.
DR OrthoDB; 1753647at2759; -.
DR Proteomes; UP000030689; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR PANTHER; PTHR13018:SF141; OS01G0950900 PROTEIN; 1.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 2.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023303};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030689};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 100..119
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 146..165
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 343..367
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 399..419
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 431..454
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 491..509
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 529..546
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 552..569
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 590..611
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 617..634
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 6..167
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 188..254
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 258..330
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 342..609
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
SQ SEQUENCE 704 AA; 80529 MW; FDD3DB8C89A28C0D CRC64;
MTPESLIASA SINIGLAVLA LWLFSVLKKQ PRNAVIYYAR RLSDLHRPDL PLHSSFSLPR
FLPSVAWIPR AFGVPEDDIL RRHGLDALVF IRLFKFGIRF FLLCSILGVS LLLPVDYYSE
SDLPTRREYS MDAFTISNIT RGSNKLWVHF SCLWFISFYA LFLLYKEYKE ILVKRLQQMR
ELKHRADQFT VLVRQVPLCP EHKTRGCGVD HFFSKHHPFS YHSHQMLYNG KDLEYLLGKQ
KKLKRELEDK RHTQDHKQIS TSEEKLQEIT HKIIHLQSET MLREKELPVA FVTFKSRRSA
ALAAQTQQHS NPLELITEMA PEPRDVSWRN LAIPHKILPL NKIGVILAAA LLTIFFAIPV
TAVQGIAKYE KLKKWFPPAM AIEFIPGLSS VVTGYLPSAI LKGFMYIVPY AMLGMAYLGG
STSKSKEEIK ACNMVFYFLM GNVFFLSLIS GSLLDEIGEY FTHPRDIPSH LAAAVSSQGE
FFMTYILTDG LSGFSLEILQ LGLITFDIIR SYTYGRGEER NPYLFSFPYF RVIPTVSLLI
MIGMIYAVVA PLMLPFLVGY FCLGYIVYFN QMEDVYETTY DTCGRFWPFI HHYIFVSIIL
MQVTMVGLFG LKSKPSAAIA TIPLILITIA YNEYCKIRFL PSFKHFPIQT AVEIDEVDEK
NGEIEAHYVD AAMAYKRYQP CLERVSLAES PANMSQPLLG TDSI
//
