ID V4M582_EUTSA Unreviewed; 813 AA.
AC V4M582;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=AAA+ ATPase domain-containing protein {ECO:0000259|SMART:SM00382};
GN ORFNames=EUTSA_v10016261mg {ECO:0000313|EMBL:ESQ51404.1};
OS Eutrema salsugineum (Saltwater cress) (Sisymbrium salsugineum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema.
OX NCBI_TaxID=72664 {ECO:0000313|EMBL:ESQ51404.1, ECO:0000313|Proteomes:UP000030689};
RN [1] {ECO:0000313|EMBL:ESQ51404.1, ECO:0000313|Proteomes:UP000030689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23518688; DOI=10.3389/fpls.2013.00046;
RA Yang R., Jarvis D.E., Chen H., Beilstein M.A., Grimwood J., Jenkins J.,
RA Shu S., Prochnik S., Xin M., Ma C., Schmutz J., Wing R.A.,
RA Mitchell-Olds T., Schumaker K.S., Wang X.;
RT "The Reference Genome of the Halophytic Plant Eutrema salsugineum.";
RL Front. Plant Sci. 4:46-46(2013).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: In the C-terminal section; belongs to the peptidase M41
CC family. {ECO:0000256|ARBA:ARBA00010044}.
CC -!- SIMILARITY: In the N-terminal section; belongs to the AAA ATPase
CC family. {ECO:0000256|ARBA:ARBA00010550}.
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DR EMBL; KI517385; ESQ51404.1; -; Genomic_DNA.
DR RefSeq; XP_006409951.1; XM_006409888.1.
DR AlphaFoldDB; V4M582; -.
DR STRING; 72664.V4M582; -.
DR MEROPS; M41.022; -.
DR EnsemblPlants; ESQ51404; ESQ51404; EUTSA_v10016261mg.
DR GeneID; 18027840; -.
DR Gramene; ESQ51404; ESQ51404; EUTSA_v10016261mg.
DR KEGG; eus:EUTSA_v10016261mg; -.
DR eggNOG; KOG0731; Eukaryota.
DR OMA; FQEEFPF; -.
DR OrthoDB; 9585at2759; -.
DR Proteomes; UP000030689; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005739; C:mitochondrion; IEA:EnsemblPlants.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd19501; RecA-like_FtsH; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.1690.20; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.20.58.760; Peptidase M41; 1.
DR HAMAP; MF_01458; FtsH; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041569; AAA_lid_3.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR005936; FtsH.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011546; Pept_M41_FtsH_extracell.
DR InterPro; IPR000642; Peptidase_M41.
DR InterPro; IPR037219; Peptidase_M41-like.
DR NCBIfam; TIGR01241; FtsH_fam; 1.
DR PANTHER; PTHR43655; ATP-DEPENDENT PROTEASE; 1.
DR PANTHER; PTHR43655:SF35; ATP-DEPENDENT ZINC METALLOPROTEASE FTSH 3, MITOCHONDRIAL; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF17862; AAA_lid_3; 1.
DR Pfam; PF06480; FtsH_ext; 1.
DR Pfam; PF01434; Peptidase_M41; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF140990; FtsH protease domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00674; AAA; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000030689};
KW Transit peptide {ECO:0000256|ARBA:ARBA00022946};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 359..498
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 95..125
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 780..813
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 95..124
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 813 AA; 89541 MW; 7E0D11C49337C13F CRC64;
MKMIFSKLGR SVIQSSRSRG LLYGGGVRWA RLLASPAIEA ASVNQVDGGG LGFLRRHFAS
LTGGKGLVNN DLTGVFANPR IRRFFSDEAP KKKNYENYFP KDTKQEPKSD QKSESKEGSD
KNESENLGDM FMNRFQNLLI PLLALAVFFS SFSFGSGDQQ QISFQEFKNK LLEPGLVDHI
DVSNKSVAKV YVRSTPRSQQ TTQDVVVQGD GSRIPVKKTG GQYKYYFNIG SVDSFEEKLE
EAQEALGVDP HEFVPVTYVS EMVWYQEFMR FAPTILLLGT LIYGARRMQG GLGVGGTGGK
NGRGIFNIGK ATITRADKNS KNKIYFKDVA GCDEAKQEIM EFVHFLKNPK KYEDLGAKIP
KGALLVGPPG TGKTLLAKAT AGESGVPFLS ISGSDFMEMF VGVGPSRVRH LFQEARQSAP
SIIFIDEIDA IGRARGRGGL GGNDERESTL NQLLVEMDGF GTTAGVVVLA GTNRPDILDK
ALLRPGRFDR QITIDKPDIK GRDQIFQIYL KKIKLDHEPS YYSQRLSALT PGFAGADIAN
VCNEAALIAA RQGGATVTMA HFESAIDRVI GGLEKKNRVI SKLERRTVAY HESGHAVAGW
FLEHAEPLLK VTIVPRGTAA LGFAQYVPNE NLLMTKEQLF DMTCMTLGGR AAEQVLIGRI
STGAQNDLEK VTKMTYAQVA VYGFSDKVGL LSFPPRDDGY DFSKPYSNKT GAIIDEEVRD
WVSKAYEKTV ELIEEHKEQV AQIAELLLEK EVLHQDDLLK VLGERPFKSA EVTNYDRFKS
GFEESEKEET TTTVTPVVDE GAPPPLEPQV VPT
//
