ID V4M656_EUTSA Unreviewed; 892 AA.
AC V4M656;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=Histone-lysine N-methyltransferase {ECO:0008006|Google:ProtNLM};
GN ORFNames=EUTSA_v10016217mg {ECO:0000313|EMBL:ESQ51749.1};
OS Eutrema salsugineum (Saltwater cress) (Sisymbrium salsugineum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema.
OX NCBI_TaxID=72664 {ECO:0000313|EMBL:ESQ51749.1, ECO:0000313|Proteomes:UP000030689};
RN [1] {ECO:0000313|EMBL:ESQ51749.1, ECO:0000313|Proteomes:UP000030689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23518688; DOI=10.3389/fpls.2013.00046;
RA Yang R., Jarvis D.E., Chen H., Beilstein M.A., Grimwood J., Jenkins J.,
RA Shu S., Prochnik S., Xin M., Ma C., Schmutz J., Wing R.A.,
RA Mitchell-Olds T., Schumaker K.S., Wang X.;
RT "The Reference Genome of the Halophytic Plant Eutrema salsugineum.";
RL Front. Plant Sci. 4:46-46(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; KI517385; ESQ51749.1; -; Genomic_DNA.
DR RefSeq; XP_006410296.1; XM_006410233.1.
DR AlphaFoldDB; V4M656; -.
DR STRING; 72664.V4M656; -.
DR EnsemblPlants; ESQ51749; ESQ51749; EUTSA_v10016217mg.
DR Gramene; ESQ51749; ESQ51749; EUTSA_v10016217mg.
DR KEGG; eus:EUTSA_v10016217mg; -.
DR eggNOG; KOG1080; Eukaryota.
DR OMA; LAGHAMW; -.
DR Proteomes; UP000030689; Unassembled WGS sequence.
DR GO; GO:0000785; C:chromatin; IEA:EnsemblPlants.
DR GO; GO:0005737; C:cytoplasm; IEA:EnsemblPlants.
DR GO; GO:0005886; C:plasma membrane; IEA:EnsemblPlants.
DR GO; GO:0048188; C:Set1C/COMPASS complex; IEA:EnsemblPlants.
DR GO; GO:0003682; F:chromatin binding; IEA:EnsemblPlants.
DR GO; GO:0140999; F:histone H3K4 trimethyltransferase activity; IEA:EnsemblPlants.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0010314; F:phosphatidylinositol-5-phosphate binding; IEA:EnsemblPlants.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IEA:EnsemblPlants.
DR GO; GO:0009738; P:abscisic acid-activated signaling pathway; IEA:EnsemblPlants.
DR GO; GO:0040029; P:epigenetic regulation of gene expression; IEA:EnsemblPlants.
DR GO; GO:0009910; P:negative regulation of flower development; IEA:EnsemblPlants.
DR GO; GO:1904961; P:quiescent center organization; IEA:EnsemblPlants.
DR GO; GO:2000023; P:regulation of lateral root development; IEA:EnsemblPlants.
DR GO; GO:2000067; P:regulation of root morphogenesis; IEA:EnsemblPlants.
DR GO; GO:0090333; P:regulation of stomatal closure; IEA:EnsemblPlants.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:EnsemblPlants.
DR GO; GO:0009414; P:response to water deprivation; IEA:EnsemblPlants.
DR GO; GO:0010093; P:specification of floral organ identity; IEA:EnsemblPlants.
DR GO; GO:0010228; P:vegetative to reproductive phase transition of meristem; IEA:EnsemblPlants.
DR CDD; cd15662; ePHD_ATX1_2_like; 1.
DR CDD; cd20142; PWWP_AtATX1-like; 1.
DR CDD; cd10518; SET_SETD1-like; 1.
DR CDD; cd20404; Tudor_Agenet_AtEML-like; 1.
DR Gene3D; 2.30.30.140; -; 2.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR041956; ATX1/2_ePHD.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR003616; Post-SET_dom.
DR InterPro; IPR000313; PWWP_dom.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13793:SF153; HISTONE H3-LYSINE(4) N-TRIMETHYLTRANSFERASE ATX1; 1.
DR PANTHER; PTHR13793; PHD FINGER PROTEINS; 1.
DR Pfam; PF00855; PWWP; 1.
DR Pfam; PF00856; SET; 1.
DR Pfam; PF13832; zf-HC5HC2H_2; 1.
DR SMART; SM00293; PWWP; 1.
DR SMART; SM00317; SET; 1.
DR SUPFAM; SSF82199; SET domain; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 2.
DR PROSITE; PS51805; EPHD; 1.
DR PROSITE; PS50868; POST_SET; 1.
DR PROSITE; PS50812; PWWP; 1.
DR PROSITE; PS50280; SET; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000030689};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 290..354
FT /note="PWWP"
FT /evidence="ECO:0000259|PROSITE:PS50812"
FT DOMAIN 492..617
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT DOMAIN 730..848
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT DOMAIN 854..870
FT /note="Post-SET"
FT /evidence="ECO:0000259|PROSITE:PS50868"
FT REGION 152..172
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 393..418
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 393..417
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 892 AA; 100595 MW; DD9B0B35F806B1F0 CRC64;
MACVSDETQI EIDTQDHVEA PIRYASIELM YSVPSSSLCN VAVGSQSLMS KKVIKAQKLS
MIDQFEVQGS CVSSIADKCK LLTRRPEIVY VYCRRRKRTR RESFLESVNT ESLKLDDASA
WFEEEKKQKQ RRIGNCELEK LDVDWSGLRS CGNKQNGSSR RKGSSVKNQD KLSLASTSAK
RWVRLSYDGV DPKSFIGLQC KVFWPLDAVW YTGSIAGYSL ERKRHNVKYE DGYEEDIKLD
RERIKFFVSR EEMNLLHLSL CTSDVTLGGH DYDEMVVLAA ASEDCQDFEP GDIVWAKLAG
HAMWPAVIVE ESVIGERKGL NNKLSGRGSL LVQFFGTHDF ARIKGKQATS FIKGLLSPSH
LKCKQPRFEE GMQEAKMYLK EHRLPERMSQ LQKGADSNYS DRANCTEEGS SNSGGDHFND
GEVWLRPTEI VDFRHQDHPT GYRPVRVDWK DLDKCNVCHM DEVHASCYGE LEPCDGALWL
CNLCRPGAPD ITPRCCLCPV VGGAMKPTTD GRWAHLACAI WIPETCLSDV QKMEPIDGVK
KVSKDRWKLL CTICGVSYGA CIQCSNCSCR VAYHPLCARA AGLCVELESE NRIFLQSTED
EEADQCIRML SFCKRHRQTS TACLESEDMI KTTTQKTSEY LPPPNPSGCA RTEPYNFLGR
RGRKEPEALA AASSKRLFVE NQPYVVGGYS RNEFSTYECI HGSKVSQINT PTNILSMAEK
YSYMKETYRK RLAFGKSGIH GFGIFAKLPH RAGDMVIEYT GELVRPSIAD KREHLIYNSM
VGAGTYMFRI DEERVIDATR AGSIAHLINH SCVPNCYSRV ISVNGDEHII IFAKRDVAKW
EELTYDYRFF STDERLSCSC GFPGCRGVVN DTEAEEQQSK ICVPRSALID CI
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