ID V4MTM2_EUTSA Unreviewed; 782 AA.
AC V4MTM2;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Cation/H+ exchanger domain-containing protein {ECO:0000259|Pfam:PF00999};
GN ORFNames=EUTSA_v10010021mg {ECO:0000313|EMBL:ESQ35176.1};
OS Eutrema salsugineum (Saltwater cress) (Sisymbrium salsugineum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema.
OX NCBI_TaxID=72664 {ECO:0000313|EMBL:ESQ35176.1, ECO:0000313|Proteomes:UP000030689};
RN [1] {ECO:0000313|EMBL:ESQ35176.1, ECO:0000313|Proteomes:UP000030689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23518688; DOI=10.3389/fpls.2013.00046;
RA Yang R., Jarvis D.E., Chen H., Beilstein M.A., Grimwood J., Jenkins J.,
RA Shu S., Prochnik S., Xin M., Ma C., Schmutz J., Wing R.A.,
RA Mitchell-Olds T., Schumaker K.S., Wang X.;
RT "The Reference Genome of the Halophytic Plant Eutrema salsugineum.";
RL Front. Plant Sci. 4:46-46(2013).
CC -!- SIMILARITY: Belongs to the monovalent cation:proton antiporter 2 (CPA2)
CC transporter (TC 2.A.37) family. CHX (TC 2.A.37.4) subfamily.
CC {ECO:0000256|ARBA:ARBA00038341}.
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DR EMBL; KI517683; ESQ35176.1; -; Genomic_DNA.
DR RefSeq; XP_006416823.1; XM_006416760.1.
DR AlphaFoldDB; V4MTM2; -.
DR STRING; 72664.V4MTM2; -.
DR EnsemblPlants; ESQ35176; ESQ35176; EUTSA_v10010021mg.
DR GeneID; 18993254; -.
DR Gramene; ESQ35176; ESQ35176; EUTSA_v10010021mg.
DR KEGG; eus:EUTSA_v10010021mg; -.
DR eggNOG; KOG1650; Eukaryota.
DR OMA; KMLWEND; -.
DR OrthoDB; 6504at2759; -.
DR Proteomes; UP000030689; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR PANTHER; PTHR32468; CATION/H + ANTIPORTER; 1.
DR PANTHER; PTHR32468:SF18; CATION_H(+) ANTIPORTER 1; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030689};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 22..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 47..65
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 77..99
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 111..134
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 146..167
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 179..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 210..228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 240..258
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 292..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 322..347
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 354..377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 389..409
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 29..408
FT /note="Cation/H+ exchanger"
FT /evidence="ECO:0000259|Pfam:PF00999"
SQ SEQUENCE 782 AA; 88600 MW; 60A9C0C9A613F154 CRC64;
MDPKLLFCLP EGDALFNPLN TMFIQMACIL VFSQFFYLFL KPCGQAGPVA QILAGIVLSL
LTIIQKVHDF FLQKDSASYY IFFSFLLRTC FMFLIGLEID LDFMKRNLKS SIVITIGSLV
SCGIIWIPFL WFIVHFLQIK DDFLTLYLAF LVTLSNTASP VVIRSIIDWK LHTSEIGRLA
ISCGLFIEIT NIFLYTIVIS YISGTMIGDI FAYAFATGII ILINRFLASW LPKRNPKEKY
LSKAETLAFF ILILIIALSI ESSNINSTVF VFFIGLMFPR EGKTYRTMIQ RLSYPIHEFV
LPVYFGYIGF RFSVNSLTKR HYLVLGMTVA LTIIGKLLGV LCACSFLQIP KKYWLFLSTI
LSVKGHVGLV LLDSNLIYKK WFNPILHDMF VAVLVITTLL SGVISSLLLR IQAKGFSHQK
TSLEFHDTKE ELRVLTCVYG VRQARGLMSL ISALNGASSS SPFSPCLMHL IPLPKKRKAE
LLYHELDEDG VNSNGGDDEF GTNEGLEIND SIDSFTKDRK IMIRQVKLVA QLENMHEEIC
NATEDLRVSI VFLPFHKHQR IDGKTTNDGE VFRHMNRKVL KHAQCSIGIF VDRNITGFHQ
LHGSDSVQHV AALFFGGPDD REALSLCKWL TNNSQIHLTI IQFITDNSKM EKLVGDVVTK
DNNEVFMEIV GKDQTEDEID RCFLQEFYNR FVTTGQVGFI EKRVSNGTQT LMILREIGEM
YSLFVVGKNR GDCPMTSGMN DWEECPELGT VGDFLASSNM DVNASVLVVQ RHRNSFDSFV
DE
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