ID V4N8T3_9CAUL Unreviewed; 885 AA.
AC V4N8T3;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Nitrate reductase {ECO:0000313|EMBL:ESQ78317.1};
GN ORFNames=AEYBE204_14190 {ECO:0000313|EMBL:ESQ78317.1};
OS Asticcacaulis sp. YBE204.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Caulobacterales;
OC Caulobacteraceae; Asticcacaulis.
OX NCBI_TaxID=1282363 {ECO:0000313|EMBL:ESQ78317.1, ECO:0000313|Proteomes:UP000017808};
RN [1] {ECO:0000313|EMBL:ESQ78317.1, ECO:0000313|Proteomes:UP000017808}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YBE204 {ECO:0000313|EMBL:ESQ78317.1,
RC ECO:0000313|Proteomes:UP000017808};
RX PubMed=24463524; DOI=10.1038/nature12900;
RA Jiang C., Brown P.J., Ducret A., Brun Y.V.;
RT "Sequential evolution of bacterial morphology by co-option of a
RT developmental regulator.";
RL Nature 506:489-493(2014).
CC -!- COFACTOR:
CC Name=Mo-bis(molybdopterin guanine dinucleotide);
CC Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- PATHWAY: Nitrogen metabolism. {ECO:0000256|ARBA:ARBA00004909}.
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. NasA/NapA/NarB subfamily.
CC {ECO:0000256|ARBA:ARBA00008747}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESQ78317.1}.
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DR EMBL; AWGF01000012; ESQ78317.1; -; Genomic_DNA.
DR RefSeq; WP_023463122.1; NZ_AWGF01000012.1.
DR AlphaFoldDB; V4N8T3; -.
DR STRING; 1282363.AEYBE204_14190; -.
DR PATRIC; fig|1282363.3.peg.2761; -.
DR OrthoDB; 9816402at2; -.
DR Proteomes; UP000017808; Unassembled WGS sequence.
DR GO; GO:1990204; C:oxidoreductase complex; IEA:UniProt.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0045333; P:cellular respiration; IEA:UniProt.
DR GO; GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.
DR CDD; cd02791; MopB_CT_Nitrate-R-NapA-like; 1.
DR CDD; cd02754; MopB_Nitrate-R-NapA-like; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 2.20.25.90; ADC-like domains; 1.
DR Gene3D; 1.10.10.1100; BFD-like [2Fe-2S]-binding domain; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR007419; BFD-like_2Fe2S-bd_dom.
DR InterPro; IPR041854; BFD-like_2Fe2S-bd_dom_sf.
DR InterPro; IPR041957; CT_Nitrate-R-NapA-like.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR PANTHER; PTHR43105:SF9; NITRATE REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G15190)-RELATED; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF04324; Fer2_BFD; 1.
DR Pfam; PF04879; Molybdop_Fe4S4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR SMART; SM00926; Molybdop_Fe4S4; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Molybdenum {ECO:0000256|ARBA:ARBA00022505};
KW Nitrate assimilation {ECO:0000256|ARBA:ARBA00023063};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000017808}.
FT DOMAIN 3..58
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
SQ SEQUENCE 885 AA; 96907 MW; 0E292AD8BC119E69 CRC64;
MTPTPHQTTC PYCGVGCGVK ASLEGRKMTV RGDDTHPANQ GRLCSKGTAL GNTFGLEGRL
LEPRIRRNGQ LETATWDEAL SQVAAKFAQV VAEHGPDAIA FYVSGQLLTE DYYAVNKLAK
GYIGTANVDT NSRLCMSSAV AAHKQAFGAD LVPGTYDDLT EADMLVFSGH NAAWTHPVLY
RRIETRQNQF RVCIDPKRTD TAKAADLHLM IRPQTDIRLW NGLCAHLIAR DALDHDFIDA
HTQGYSRLMA ALSADDQSIE AVAEDCGIST IDLKKFYDAF LHTPKVVSLF SMGSNQSAQG
VHKGLALINA HLLSGKIGKP GAAPFSITGQ PNAMGGREVG GLANMLAAHM DFDEASKSLV
QRYWDSPTIA PKAGLKAVDM FEAVRSGKIK AIWIMATNPM VSMPDTNKIH EALSNCELVV
VSDVIARTDT MDMAHIQLPA AAWGEKDGTV TNSERVISRQ RNLTPLPGQV RPDWAIIAEV
GRRMNAAWET AFDWAGPDEV FAEHAGLTAF ENNGKRFLDL GGLAGMSKAE YDALQPVRWP
FKADGLPTTR LFSDGRFNTP NGRARLVPPI VRGPANQTTP EFPFHLNSTR VRDHWHTMTR
TALAPELNRH LTEPLLDIHP KDARRLHIKD GRLAVVTTAY GEAILKARVT DDVREGNLSV
PMHWTRQFAP YGRSNQLVNP AVDPMSGQPE FKHTPANVKA YNEAWHGFVM TPRDFDGELP
QWSDDTIWRR TTHAHADCFE IAGIAPLDVS AFVASLTLDD ATTGVTRRVR VENDRLTRAI
FVTPIHKKLP PRDWLLERFG DDALTDAHRA ALIIGRLPGM QDKGRIICAC RSVGEIAITA
AIADGAKTVE EIGEVTTAGT SCGSCKGELK QCLLKHAMKK EKVDA
//
