ID V4N9D3_EUTSA Unreviewed; 103 AA.
AC V4N9D3;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 54.
DE RecName: Full=Histone H4 {ECO:0000256|RuleBase:RU000528};
GN ORFNames=EUTSA_v10002735mg {ECO:0000313|EMBL:ESQ37356.1},
GN EUTSA_v10002736mg {ECO:0000313|EMBL:ESQ37418.1}, EUTSA_v10009172mg
GN {ECO:0000313|EMBL:ESQ36115.1}, EUTSA_v10010851mg
GN {ECO:0000313|EMBL:ESQ45113.1}, EUTSA_v10015098mg
GN {ECO:0000313|EMBL:ESQ42381.1}, EUTSA_v10016102mg
GN {ECO:0000313|EMBL:ESQ42347.1}, EUTSA_v10017467mg
GN {ECO:0000313|EMBL:ESQ52397.1}, EUTSA_v10017468mg
GN {ECO:0000313|EMBL:ESQ51360.1};
OS Eutrema salsugineum (Saltwater cress) (Sisymbrium salsugineum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema.
OX NCBI_TaxID=72664 {ECO:0000313|EMBL:ESQ42381.1, ECO:0000313|Proteomes:UP000030689};
RN [1] {ECO:0000313|EMBL:ESQ42381.1, ECO:0000313|Proteomes:UP000030689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23518688; DOI=10.3389/fpls.2013.00046;
RA Yang R., Jarvis D.E., Chen H., Beilstein M.A., Grimwood J., Jenkins J.,
RA Shu S., Prochnik S., Xin M., Ma C., Schmutz J., Wing R.A.,
RA Mitchell-Olds T., Schumaker K.S., Wang X.;
RT "The Reference Genome of the Halophytic Plant Eutrema salsugineum.";
RL Front. Plant Sci. 4:46-46(2013).
CC -!- FUNCTION: Core component of nucleosome. Nucleosomes wrap and compact
CC DNA into chromatin, limiting DNA accessibility to the cellular
CC machineries which require DNA as a template. Histones thereby play a
CC central role in transcription regulation, DNA repair, DNA replication
CC and chromosomal stability. DNA accessibility is regulated via a complex
CC set of post-translational modifications of histones, also called
CC histone code, and nucleosome remodeling.
CC {ECO:0000256|RuleBase:RU000528}.
CC -!- SUBUNIT: The nucleosome is a histone octamer containing two molecules
CC each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and
CC two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of
CC DNA. {ECO:0000256|RuleBase:RU000528}.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the histone H4 family.
CC {ECO:0000256|ARBA:ARBA00006564, ECO:0000256|RuleBase:RU000528}.
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DR EMBL; KI517683; ESQ36115.1; -; Genomic_DNA.
DR EMBL; KI517609; ESQ37356.1; -; Genomic_DNA.
DR EMBL; KI517609; ESQ37418.1; -; Genomic_DNA.
DR EMBL; KI517464; ESQ42347.1; -; Genomic_DNA.
DR EMBL; KI517464; ESQ42381.1; -; Genomic_DNA.
DR EMBL; KI517435; ESQ45113.1; -; Genomic_DNA.
DR EMBL; KI517385; ESQ51360.1; -; Genomic_DNA.
DR EMBL; KI517385; ESQ52397.1; -; Genomic_DNA.
DR RefSeq; XP_006400894.1; XM_006400831.1.
DR RefSeq; XP_006400928.1; XM_006400865.1.
DR RefSeq; XP_006403660.1; XM_006403597.1.
DR RefSeq; XP_006409907.1; XM_006409844.1.
DR RefSeq; XP_006410944.1; XM_006410881.1.
DR RefSeq; XP_006417762.1; XM_006417699.1.
DR RefSeq; XP_006418920.1; XM_006418857.1.
DR RefSeq; XP_006418982.1; XM_006418919.1.
DR AlphaFoldDB; V4N9D3; -.
DR SMR; V4N9D3; -.
DR STRING; 72664.V4N9D3; -.
DR EnsemblPlants; ESQ36115; ESQ36115; EUTSA_v10009172mg.
DR EnsemblPlants; ESQ37356; ESQ37356; EUTSA_v10002735mg.
DR EnsemblPlants; ESQ37418; ESQ37418; EUTSA_v10002736mg.
DR EnsemblPlants; ESQ42347; ESQ42347; EUTSA_v10016102mg.
DR EnsemblPlants; ESQ42381; ESQ42381; EUTSA_v10015098mg.
DR EnsemblPlants; ESQ45113; ESQ45113; EUTSA_v10010851mg.
DR EnsemblPlants; ESQ51360; ESQ51360; EUTSA_v10017468mg.
DR EnsemblPlants; ESQ52397; ESQ52397; EUTSA_v10017467mg.
DR GeneID; 18013997; -.
DR GeneID; 18014079; -.
DR GeneID; 18018513; -.
DR GeneID; 18019333; -.
DR GeneID; 18021234; -.
DR GeneID; 18026968; -.
DR GeneID; 18027488; -.
DR GeneID; 18994090; -.
DR Gramene; ESQ36115; ESQ36115; EUTSA_v10009172mg.
DR Gramene; ESQ37356; ESQ37356; EUTSA_v10002735mg.
DR Gramene; ESQ37418; ESQ37418; EUTSA_v10002736mg.
DR Gramene; ESQ42347; ESQ42347; EUTSA_v10016102mg.
DR Gramene; ESQ42381; ESQ42381; EUTSA_v10015098mg.
DR Gramene; ESQ45113; ESQ45113; EUTSA_v10010851mg.
DR Gramene; ESQ51360; ESQ51360; EUTSA_v10017468mg.
DR Gramene; ESQ52397; ESQ52397; EUTSA_v10017467mg.
DR KEGG; eus:EUTSA_v10002735mg; -.
DR KEGG; eus:EUTSA_v10002736mg; -.
DR KEGG; eus:EUTSA_v10009172mg; -.
DR KEGG; eus:EUTSA_v10010851mg; -.
DR KEGG; eus:EUTSA_v10015098mg; -.
DR KEGG; eus:EUTSA_v10016102mg; -.
DR KEGG; eus:EUTSA_v10017467mg; -.
DR KEGG; eus:EUTSA_v10017468mg; -.
DR eggNOG; KOG3467; Eukaryota.
DR OMA; QKEHING; -.
DR OrthoDB; 1210705at2759; -.
DR Proteomes; UP000030689; Unassembled WGS sequence.
DR GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR CDD; cd00076; H4; 1.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR InterPro; IPR035425; CENP-T/H4_C.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR001951; Histone_H4.
DR InterPro; IPR019809; Histone_H4_CS.
DR PANTHER; PTHR10484; HISTONE H4; 1.
DR PANTHER; PTHR10484:SF0; HISTONE H4; 1.
DR Pfam; PF15511; CENP-T_C; 1.
DR PRINTS; PR00623; HISTONEH4.
DR SMART; SM00417; H4; 1.
DR SUPFAM; SSF47113; Histone-fold; 1.
DR PROSITE; PS00047; HISTONE_H4; 1.
PE 3: Inferred from homology;
KW Chromosome {ECO:0000256|ARBA:ARBA00022454, ECO:0000256|RuleBase:RU000528};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU000528};
KW Nucleosome core {ECO:0000256|ARBA:ARBA00023269,
KW ECO:0000256|RuleBase:RU000528};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU000528};
KW Reference proteome {ECO:0000313|Proteomes:UP000030689}.
FT DOMAIN 39..96
FT /note="CENP-T/Histone H4 histone fold"
FT /evidence="ECO:0000259|Pfam:PF15511"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 103 AA; 11409 MW; A9FD57725A2A7598 CRC64;
MSGRGKGGKG LGKGGAKRHR KVLRDNIQGI TKPAIRRLAR RGGVKRISGL IYEETRGVLK
IFLENVIRDA VTYTEHARRK TVTAMDVVYA LKRQGRTLYG FGG
//
