ID V4NK95_EUTSA Unreviewed; 994 AA.
AC V4NK95;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
GN ORFNames=EUTSA_v10027631mg {ECO:0000313|EMBL:ESQ46786.1};
OS Eutrema salsugineum (Saltwater cress) (Sisymbrium salsugineum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema.
OX NCBI_TaxID=72664 {ECO:0000313|EMBL:ESQ46786.1, ECO:0000313|Proteomes:UP000030689};
RN [1] {ECO:0000313|EMBL:ESQ46786.1, ECO:0000313|Proteomes:UP000030689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23518688; DOI=10.3389/fpls.2013.00046;
RA Yang R., Jarvis D.E., Chen H., Beilstein M.A., Grimwood J., Jenkins J.,
RA Shu S., Prochnik S., Xin M., Ma C., Schmutz J., Wing R.A.,
RA Mitchell-Olds T., Schumaker K.S., Wang X.;
RT "The Reference Genome of the Halophytic Plant Eutrema salsugineum.";
RL Front. Plant Sci. 4:46-46(2013).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KI517416; ESQ46786.1; -; Genomic_DNA.
DR RefSeq; XP_006405333.1; XM_006405270.1.
DR AlphaFoldDB; V4NK95; -.
DR STRING; 72664.V4NK95; -.
DR EnsemblPlants; ESQ46786; ESQ46786; EUTSA_v10027631mg.
DR GeneID; 18022930; -.
DR Gramene; ESQ46786; ESQ46786; EUTSA_v10027631mg.
DR KEGG; eus:EUTSA_v10027631mg; -.
DR eggNOG; ENOG502SUNR; Eukaryota.
DR OMA; VELNMQF; -.
DR OrthoDB; 691519at2759; -.
DR Proteomes; UP000030689; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR011713; Leu-rich_rpt_3.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11017; LEUCINE-RICH REPEAT-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11017:SF334; TIR DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF07725; LRR_3; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF01582; TIR; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000030689}.
FT DOMAIN 10..174
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
SQ SEQUENCE 994 AA; 112748 MW; 9EE6CBECDF9E89DC CRC64;
MASSSSTQIR RYHVFPSFHG ADVRKRFLSH LHNYFEIKGI TTFKDQEIER GNSIGPELVK
AIRESRVSIV LFSTNYASSS WCLDELVEIL KCKEASGLIV MTIFYDVDPS SVRKQKGDFG
NAFMKTCQGK TEEVKQRWSK ALTDVANIEG EHSLNWPNEA EMIQKIARDV SNKLNVTPFR
DFDGMVGLEA HLTNLNSMLC LESDDVKMIG IWGPAGIGKT TIARALYNLL SSDYRLRCFM
GNLRGGSFRS MIGVDDYDSK LCLQNQLLSK ILNQRDMRVH HFGGIKEWLQ NQRVLIILDD
VDDLEKLEAL AREPSWFGHG SRIIVTTEDK KILKAHGIQD IYHVDFPSKN EALEIFSLSA
FKQSSVRDGF EELANRVVKF CSNLPLGLSV VGSSLRGESK NEWEIELSNM EKSLDRKIED
VLRVGYDRLS KKDQALFLHI ACFFFFHEDV DHVADMLANN SNIDVPSGLK TLTEKSLVHI
SHYRQIVMHS LLQQLGRQVV VQQSDEPGKR QFLVEAEEIR DVLENETGTS SLIGITLDTT
YIDKLYISKR AFEGMHNLQF LRIYQRLGGS FLHIKEDLEY LPRLRLLKWD YYPSKSLPAS
FQPDRLVELN MQFSNLKKLW GGIQPLAKLK NIKLDHSDRL KEIPDLSNAT NLETLSLTFC
SSLVELPSSI RNLHKLKKLL MRCCEKLRVI PTNINLASLE EVDMSNCSQL RSFPDISSNI
KTLHARNTQI KDVPASIVGR WSRCEKLAIG SRSLERLTHV PLSVTSLDLT NSDIKKIPDC
IIGLQHLVKL VVENCTKLES IQALPPSLVS LNANNCVFMK KVCCPLHKPV EALTFYNCLN
LDEEARRGII QQSVRDYICL PGKEVPAEFT HKATGKSINI PLAPGGEGTF SASSRFKACL
LLSPIKRRRF ISIVCRLRSK GDVTTKFRRS VWYYDLPPLS KHLFIFRGGE IGVGTSEITF
EFSCDDNDAK IIGCGVQCKS RDSTRNVLHM EERE
//
