ID V4P3N1_9CAUL Unreviewed; 374 AA.
AC V4P3N1;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein {ECO:0000259|Pfam:PF16576};
GN ORFNames=AEAC466_16360 {ECO:0000313|EMBL:ESQ82711.1};
OS Asticcacaulis sp. AC466.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Caulobacterales;
OC Caulobacteraceae; Asticcacaulis.
OX NCBI_TaxID=1282362 {ECO:0000313|EMBL:ESQ82711.1, ECO:0000313|Proteomes:UP000017826};
RN [1] {ECO:0000313|EMBL:ESQ82711.1, ECO:0000313|Proteomes:UP000017826}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AC466 {ECO:0000313|EMBL:ESQ82711.1,
RC ECO:0000313|Proteomes:UP000017826};
RX PubMed=24463524; DOI=10.1038/nature12900;
RA Jiang C., Brown P.J., Ducret A., Brun Y.V.;
RT "Sequential evolution of bacterial morphology by co-option of a
RT developmental regulator.";
RL Nature 506:489-493(2014).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESQ82711.1}.
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DR EMBL; AWGE01000017; ESQ82711.1; -; Genomic_DNA.
DR AlphaFoldDB; V4P3N1; -.
DR STRING; 1282362.AEAC466_16360; -.
DR PATRIC; fig|1282362.3.peg.3234; -.
DR eggNOG; COG0845; Bacteria.
DR OrthoDB; 7265739at2; -.
DR Proteomes; UP000017826; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469:SF15; HLYD FAMILY OF SECRETION PROTEINS; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000017826}.
FT DOMAIN 81..280
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
SQ SEQUENCE 374 AA; 38844 MW; F040DA2C5C9E946D CRC64;
MGMTSGSIEG RKPGFRAVFA VGVSLALVLG SGLSACGEKS KTDGDKKGGA SGHAAVVNFA
TARDATAPVK IAGTGTISAW QEVIVGAETG GLTAVALLVD EGQSVKQGQP LLRMNDVLLQ
AQLKQAQANY NQANKAYQRA QSLFQQGYLS AAALDNAEAS KLTTEAAMQT AQTQLSMATV
RAPVSGMVTH RTAVLGQNIQ QGAELFRIVR DGRIELNMQV VESDLHNIHA GMAATVTSES
TGPVTGSVRI VTPMVDPSTR LGYARISVPW SSGLRPGMFA SGSIDAGMQN VLLIPQLAVV
YTENVPNVYV IGVDNKAHLR KVVIGSTTPT KDIIIKEGLS VGDRVVTTGA GFLNDGDAVK
ATPQPGQPQT GGEH
//
