ID V4PA94_9CAUL Unreviewed; 718 AA.
AC V4PA94;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Methyltransferase {ECO:0008006|Google:ProtNLM};
GN ORFNames=AEAC466_09700 {ECO:0000313|EMBL:ESQ84009.1};
OS Asticcacaulis sp. AC466.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Caulobacterales;
OC Caulobacteraceae; Asticcacaulis.
OX NCBI_TaxID=1282362 {ECO:0000313|EMBL:ESQ84009.1, ECO:0000313|Proteomes:UP000017826};
RN [1] {ECO:0000313|EMBL:ESQ84009.1, ECO:0000313|Proteomes:UP000017826}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AC466 {ECO:0000313|EMBL:ESQ84009.1,
RC ECO:0000313|Proteomes:UP000017826};
RX PubMed=24463524; DOI=10.1038/nature12900;
RA Jiang C., Brown P.J., Ducret A., Brun Y.V.;
RT "Sequential evolution of bacterial morphology by co-option of a
RT developmental regulator.";
RL Nature 506:489-493(2014).
CC -!- PATHWAY: Amino-acid biosynthesis; ergothioneine biosynthesis.
CC {ECO:0000256|ARBA:ARBA00037882}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESQ84009.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AWGE01000008; ESQ84009.1; -; Genomic_DNA.
DR AlphaFoldDB; V4PA94; -.
DR STRING; 1282362.AEAC466_09700; -.
DR PATRIC; fig|1282362.3.peg.1916; -.
DR eggNOG; COG1262; Bacteria.
DR eggNOG; COG4301; Bacteria.
DR OrthoDB; 9768004at2; -.
DR Proteomes; UP000017826; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0052699; P:ergothioneine biosynthetic process; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.90.1580.10; paralog of FGE (formylglycine-generating enzyme); 2.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR024775; DinB-like.
DR InterPro; IPR034660; DinB/YfiT-like.
DR InterPro; IPR017806; EgtB.
DR InterPro; IPR035094; EgtD.
DR InterPro; IPR019257; MeTrfase_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR005532; SUMF_dom.
DR InterPro; IPR042095; SUMF_sf.
DR NCBIfam; TIGR03440; egtB_TIGR03440; 1.
DR NCBIfam; TIGR03438; egtD_ergothio; 1.
DR PANTHER; PTHR43397; ERGOTHIONEINE BIOSYNTHESIS PROTEIN 1; 1.
DR PANTHER; PTHR43397:SF1; ERGOTHIONEINE BIOSYNTHESIS PROTEIN 1; 1.
DR Pfam; PF12867; DinB_2; 1.
DR Pfam; PF03781; FGE-sulfatase; 1.
DR Pfam; PF10017; Methyltransf_33; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 1.
DR SUPFAM; SSF109854; DinB/YfiT-like putative metalloenzymes; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000017826};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 26..153
FT /note="DinB-like"
FT /evidence="ECO:0000259|Pfam:PF12867"
FT DOMAIN 191..324
FT /note="Sulfatase-modifying factor enzyme"
FT /evidence="ECO:0000259|Pfam:PF03781"
FT DOMAIN 417..717
FT /note="Histidine-specific methyltransferase SAM-dependent"
FT /evidence="ECO:0000259|Pfam:PF10017"
SQ SEQUENCE 718 AA; 79314 MW; 5B05C0BFEA6E8B18 CRC64;
MNTAPCQMPG QMRAAPQDSL LDLYLTLRAR TLDLVAPLSP EDMVVQSMPD ASPAKWHLAH
TTWFFETFLL NGQPHYKAFD PDYAFLFNSY YEALGPRQPR AQRGLLTRPP LDDILAYRRH
VDTHMHALLA GDINESTIDF LRLGLAHEEQ HQELLLMDIL HLFSQSPLRP AAAPDWPGDD
SGRAGRFQLR PGGLVDIGHS GCGFAFDNET PRHKVWLQPF EISDRLVTNG DWLAFMADGG
YARPDLWLSD GWTQVQTNGW QAPAYWHATS EGWREMTLGG AVPVMPDTPV THVSFYEADA
FARWSGARLP TEAEWEAAAS DGALEQVDTV AWQWTASAYL PYPGFTPGSG AVGEYNGKFM
SGQMVLRGGC AFTPPGHARP SYRNFFRPEQ RWMRSGVRLA RDLHAGVAAT DRDEATFASD
VVAGLSARQK SLSPKYFYDA TGSELFEAIC RTPEYYPTRT ESALLADIAA ELTAAIPADA
VLVEFGSGAS DKTRRLLDAA PQITAYVPID ISDDALRQAT LRLNRDYPNL VVTPVVGDFT
TLLDLPRALR GRSLVGFFPG STIGNFSVPE ARQLLRNMRA MLGSDARLIV GADMVKDEAT
LVATYNDAAG ITAEFNKNVL RRINAELAGT FDLNAFDHLA IWNAEYARME MHLVSRVDQI
VHAAGHTFAF KAGERLHTEN SHKFTRQSFG ALAADAGFTV EQVWVSPAPE FAVFSLKA
//
