ID V4RR16_9CAUL Unreviewed; 243 AA.
AC V4RR16;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=Heme exporter protein C {ECO:0000256|ARBA:ARBA00016463, ECO:0000256|RuleBase:RU364092};
DE AltName: Full=Cytochrome c-type biogenesis protein {ECO:0000256|RuleBase:RU364092};
GN Name=ccmC {ECO:0000256|RuleBase:RU364092};
GN ORFNames=ABENE_04700 {ECO:0000313|EMBL:ESQ93618.1};
OS Asticcacaulis benevestitus DSM 16100 = ATCC BAA-896.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Caulobacterales;
OC Caulobacteraceae; Asticcacaulis.
OX NCBI_TaxID=1121022 {ECO:0000313|EMBL:ESQ93618.1, ECO:0000313|Proteomes:UP000017837};
RN [1] {ECO:0000313|EMBL:ESQ93618.1, ECO:0000313|Proteomes:UP000017837}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16100 {ECO:0000313|EMBL:ESQ93618.1,
RC ECO:0000313|Proteomes:UP000017837};
RX PubMed=24463524; DOI=10.1038/nature12900;
RA Jiang C., Brown P.J., Ducret A., Brun Y.V.;
RT "Sequential evolution of bacterial morphology by co-option of a
RT developmental regulator.";
RL Nature 506:489-493(2014).
CC -!- FUNCTION: Required for the export of heme to the periplasm for the
CC biogenesis of c-type cytochromes. {ECO:0000256|ARBA:ARBA00002442,
CC ECO:0000256|RuleBase:RU364092}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|RuleBase:RU364092}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CcmC/CycZ/HelC family.
CC {ECO:0000256|ARBA:ARBA00005840, ECO:0000256|RuleBase:RU364092}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU364092}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESQ93618.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AWGB01000007; ESQ93618.1; -; Genomic_DNA.
DR RefSeq; WP_018082450.1; NZ_AWGB01000007.1.
DR AlphaFoldDB; V4RR16; -.
DR STRING; 1121022.GCA_000376105_02779; -.
DR PATRIC; fig|1121022.4.peg.933; -.
DR eggNOG; COG0755; Bacteria.
DR OrthoDB; 9778550at2; -.
DR Proteomes; UP000017837; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0015232; F:heme transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.
DR InterPro; IPR002541; Cyt_c_assembly.
DR InterPro; IPR003557; Cyt_c_biogenesis_CcmC.
DR InterPro; IPR045062; Cyt_c_biogenesis_CcsA/CcmC.
DR NCBIfam; TIGR01191; ccmC; 1.
DR PANTHER; PTHR30071:SF17; CYTOCHROME C ASSEMBLY PROTEIN-RELATED; 1.
DR PANTHER; PTHR30071; HEME EXPORTER PROTEIN C; 1.
DR Pfam; PF01578; Cytochrom_C_asm; 1.
DR PRINTS; PR01386; CCMCBIOGNSIS.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|RuleBase:RU364092};
KW Cell membrane {ECO:0000256|RuleBase:RU364092};
KW Cytochrome c-type biogenesis {ECO:0000256|RuleBase:RU364092};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364092};
KW Reference proteome {ECO:0000313|Proteomes:UP000017837};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364092};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364092}; Transport {ECO:0000256|RuleBase:RU364092}.
FT TRANSMEM 59..84
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364092"
FT TRANSMEM 96..117
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364092"
FT TRANSMEM 129..149
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364092"
FT TRANSMEM 161..181
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364092"
FT TRANSMEM 201..222
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364092"
FT DOMAIN 31..184
FT /note="Cytochrome c assembly protein"
FT /evidence="ECO:0000259|Pfam:PF01578"
SQ SEQUENCE 243 AA; 26919 MW; FE9926CF8AB36601 CRC64;
MSEGMINFLA NPERFTRVTR PLRSWLAGLA ALLLVWGLYL CFASPEDYQQ GDTVRIMYVH
VPAAWLGLAI YGAMGLSSFF GLIFRHALAD AAAKALAPIG AVFTALALAT GSLWGMPMWG
TPWQWDGRMT SELVLLLFYI GYIALHASIE DEVRAAKSTA ILAMVGLVNL PIVHFSVQWW
NSLHQGGSIF VKGGPTVGAE MLWPLFVMVG AYHALTLWLF LIRLDSEILA RKYRALRARL
SFN
//
