ID V4XVN6_9ARCH Unreviewed; 386 AA.
AC V4XVN6;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Aminomethyltransferase {ECO:0000313|EMBL:ESS04251.1};
DE EC=2.1.2.10 {ECO:0000313|EMBL:ESS04251.1};
GN ORFNames=A07HR67_01240 {ECO:0000313|EMBL:ESS04251.1};
OS uncultured archaeon A07HR67.
OC Archaea; environmental samples.
OX NCBI_TaxID=1412871 {ECO:0000313|EMBL:ESS04251.1, ECO:0000313|Proteomes:UP000030660};
RN [1] {ECO:0000313|Proteomes:UP000030660}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24335829;
RA Podell S., Emerson J.B., Jones C.M., Ugalde J.A., Welch S.,
RA Heidelberg K.B., Banfield J.F., Allen E.E.;
RT "Seasonal fluctuations in ionic concentrations drive microbial succession
RT in a hypersaline lake community.";
RL ISME J. 0:0-0(2013).
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DR EMBL; KI543165; ESS04251.1; -; Genomic_DNA.
DR AlphaFoldDB; V4XVN6; -.
DR STRING; 1412871.A07HR67_01240; -.
DR PATRIC; fig|1412871.3.peg.1292; -.
DR Proteomes; UP000030660; Unassembled WGS sequence.
DR GO; GO:0004047; F:aminomethyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR InterPro; IPR028896; GCST/YgfZ/DmdA.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR InterPro; IPR017703; YgfZ/GcvT_CS.
DR NCBIfam; TIGR03317; ygfZ_signature; 1.
DR PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR PIRSF; PIRSF006487; GcvT; 1.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:ESS04251.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000030660};
KW Transferase {ECO:0000313|EMBL:ESS04251.1};
KW Transit peptide {ECO:0000256|ARBA:ARBA00022946}.
FT DOMAIN 5..241
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 305..369
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..27
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 386 AA; 40530 MW; C2491EA3FEFAE75C CRC64;
MTLVSDAHAD HEARYRDRGG RQVVDHYGKP DRVGKAVRNV VGTIEMGYGV LAVTGEDRVD
FVDNAVTNRV PSADGRGVYA LLCDPQGGIE TDMYVYNADE RLLVFVPPER AEPVREDWAS
KTFIQDVAIE DVSADLGVFG VHGPKSTEKV ASVLNGAGAP EEPLTFVRGS MVDAGVTVIA
TDAPLGEEGY EVVCAAADAP DVFDTLVNRG LNAAPFGYRT WETLGLEAGT PLFEHELEGE
IPNVAGIRNA LDFEKGCYVG QEVVSRVENQ GRPSGRLVGL TLDGLTDALA AVDGDADPET
VTARLPDPGA AVFEGDEAIG SVTRAAVGPA TDAPIAFGLV DFGRATGSVT VRVDGTEVAA
SRTPLPFVDG SARSGRLPTY PGADDS
//
