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Database: UniProt
Entry: V4YQN3_TOXGV
LinkDB: V4YQN3_TOXGV
Original site: V4YQN3_TOXGV 
ID   V4YQN3_TOXGV            Unreviewed;       923 AA.
AC   V4YQN3;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   31-JUL-2019, entry version 23.
DE   SubName: Full=Inward rectifier potassium channel protein {ECO:0000313|EMBL:ESS30554.1};
GN   ORFNames=TGVEG_284530 {ECO:0000313|EMBL:ESS30554.1};
OS   Toxoplasma gondii (strain ATCC 50861 / VEG).
OC   Eukaryota; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC   Eucoccidiorida; Eimeriorina; Sarcocystidae; Toxoplasma.
OX   NCBI_TaxID=432359 {ECO:0000313|EMBL:ESS30554.1, ECO:0000313|Proteomes:UP000002226};
RN   [1] {ECO:0000313|Proteomes:UP000002226}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 50861 / VEG {ECO:0000313|Proteomes:UP000002226};
RA   Lorenzi H., Inman J., Amedeo P., Brunk B., Roos D., Caler E.;
RT   "Annotation of Toxoplasma gondii VEG.";
RL   Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:ESS30554.1}.
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DR   EMBL; AAYL02000239; ESS30554.1; -; Genomic_DNA.
DR   EnsemblProtists; ESS30554; ESS30554; TGVEG_284530.
DR   OMA; CRASAFG; -.
DR   Proteomes; UP000002226; Partially assembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 2.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 2.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002226};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000313|EMBL:ESS30554.1};
KW   Ion transport {ECO:0000256|RuleBase:RU003822};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002226};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822}.
FT   TRANSMEM    396    422       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    466    487       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      384    491       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      820    919       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   REGION        1     47       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      252    293       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      565    598       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      614    673       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS     32     47       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    268    292       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    575    596       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    626    645       Polyampholyte. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS    646    662       Polar. {ECO:0000256|SAM:MobiDB-lite}.
SQ   SEQUENCE   923 AA;  100098 MW;  F57AF40F637E8DEC CRC64;
     MSPSSREGGP HPVVPLGGGP SSPASPPQKG DEELGTQRQA SFRSSRGTAA FESAAAAMAG
     SFSLPLGPEA GVCRTPLLAS LSSPLESETG PCSQPNARDV WPSLCFAHSS AARHATERLV
     GDAPRSRTEC VPPSLIFHHS TASFAHRASP SLCPPGHDAS FRPTTDVLPP SPRGPFFLVD
     DDSPSKFVSC SAGCCLQHSP RRLREAPEES LHFAASFDCA SDAGNHGLDA DDQSTPRGLC
     RASAFGLSLP FSSSATRRLP HPPDRLGSES RNSYSRGATH PLLPSSQPYS GDTLEDEARR
     VCRGCCRSAR KRDGRHDFEF SAQRHAGCGL EGRERSLETR DCRDQGRYSR EGNRQNVQAF
     LGSGGTYNVL HKWRYTHGYL DFILNDRFHV ILSMKWAHLV FLVFAVVVGW AAFLALILAV
     LTGGEIQRCL GPDAANVLDY YFFVIETMFA IGYGSPRAPT CQTTSLFVTP TAVSGILINS
     VVLGVVFQKF SAASKRKWAL AFSNCLVGQP SFPVPSHLVI NSSVSLEKGP HLPPREMVYG
     CCASVHDGGN PGLEAEQDCE NGDPGLRCRQ ESASTGDVCG ETAERTQSSE GEGPSTTRDA
     QEMLELNRRI DVAIESSQSE ADGNEAAPAS HRRTRRSRTD EQKSDGSDAS PGSASPCCRT
     GATSEQDGEA HRDTRQETFA AVGVFACRGG HRDLTATGLS QTDSCSYDVN GEREEAEGFG
     FDASEDRQPC SRAREETSLK SALTAPSISG HLSSFGPQDL PHSLCRAPSS STWQHYRLSF
     RVINVTHHSF FNPKLCLYLL KHSDRGLRIR QFPTFRTDTP LEFLEMPITV TVDTCDRDCP
     LREVTADELR HDGNAYEILS LLSFTDNHTS RPVEIRKSWS LRSIKWGEKF IPIVRPPSAL
     TVSAGGYEVD VDALSTTERA QLC
//
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