ID V4ZGI0_TOXGV Unreviewed; 1037 AA.
AC V4ZGI0; A0A0F7UUL0;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=ATPase, AAA family protein {ECO:0000313|EMBL:ESS32971.1};
DE SubName: Full=Heat shock protein, putative {ECO:0000313|EMBL:CEL73882.1};
GN ORFNames=BN1205_046770 {ECO:0000313|EMBL:CEL73882.1}, TGVEG_202580
GN {ECO:0000313|EMBL:ESS32971.1};
OS Toxoplasma gondii (strain ATCC 50861 / VEG).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Sarcocystidae; Toxoplasma.
OX NCBI_TaxID=432359 {ECO:0000313|EMBL:ESS32971.1, ECO:0000313|Proteomes:UP000002226};
RN [1] {ECO:0000313|EMBL:ESS32971.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VEG {ECO:0000313|EMBL:ESS32971.1};
RA Paulsen I.;
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50861 / VEG {ECO:0000313|Proteomes:UP000002226};
RA Lorenzi H., Inman J., Amedeo P., Brunk B., Roos D., Caler E.;
RT "Annotation of Toxoplasma gondii VEG.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ESS32971.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VEG {ECO:0000313|EMBL:ESS32971.1};
RA Sibley D., Venepally P., Karamycheva S., Hadjithomas M., Khan A., Brunk B.,
RA Roos D., Caler E., Lorenzi H.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:CEL73882.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VEG {ECO:0000313|EMBL:CEL73882.1};
RX PubMed=25875305; DOI=10.1371/journal.pone.0124473;
RA Ramaprasad A., Mourier T., Naeem R., Malas T.B., Moussa E., Panigrahi A.,
RA Vermont S.J., Otto T.D., Wastling J., Pain A.;
RT "Comprehensive Evaluation of Toxoplasma gondii VEG and Neospora caninum LIV
RT Genomes with Tachyzoite Stage Transcriptome and Proteome Defines Novel
RT Transcript Features.";
RL PLoS ONE 10:e0124473-e0124473(2015).
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DR EMBL; LN714496; CEL73882.1; -; Genomic_DNA.
DR EMBL; AAYL02000119; ESS32971.1; -; Genomic_DNA.
DR AlphaFoldDB; V4ZGI0; -.
DR STRING; 432359.V4ZGI0; -.
DR PaxDb; 5811-TGME49_002580; -.
DR EnsemblProtists; ESS32971; ESS32971; TGVEG_202580.
DR VEuPathDB; ToxoDB:TGVEG_202580; -.
DR eggNOG; KOG1051; Eukaryota.
DR OMA; KTHNAMN; -.
DR Proteomes; UP000002226; Partially assembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF190; CLP R DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00870; CLPAB_1; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000002226};
KW Stress response {ECO:0000313|EMBL:CEL73882.1}.
FT DOMAIN 353..497
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 681..830
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 908..998
FT /note="Clp ATPase C-terminal"
FT /evidence="ECO:0000259|SMART:SM01086"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 100..143
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 569..596
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1037 AA; 112898 MW; 145FD7F9FA37788C CRC64;
MTQKQRSSAP SCDPPCPGQA IRAPPVSSHA LSVVAWSRNS FRPPYQSPSS YPRVSSRRSR
LSSGFSSPMF HRLVSPVVRL LLLLGLLSLS RLPSAFGAQY PSDSGSSLGS GFPPGKNGRG
SDGSSDSGNG EGPGDLTPPA LLDRHKPTAT RQNFTDAASD LLDCVEQLAW MLQHPELSRV
HLVACLLDMP GDTTVPTALE KAGGKSADLR KDMHNLLIRM PQSVTPLSYG EARSRSELKR
VIIDAYNEAQ SRGHRLVGVH DLVTALARCD RFRARLANVG TDVSVFLKLV TSAFIVHTEA
EERKATPART GSQEWIKTFG VDMTEQAKEG KIGTVTGREA EIEQITSVMS RMSKANCLLI
GEPGVGKTAV VEGLAKRIVD GDVPDALLGV QVFSLDVGSL LSGSSMRGEF ERRMKGILDY
LFASDRSTIL FIDEIHTLMG AGKADGPMDA ANLLKPALAR GALRVIGATT RAEYRKHIER
DMAFARRFVT IEMKEPDVAK TIIMLKGIRK NLENHHKLTI TDGALVAAAT LSDRYIKSRQ
LPDKAIDLID DACAIKKVKS LRRLMNERAA NEEKNGNGGS GDASSSANGD GEKKRDDLEK
LEAEIAKEAE DADALTDADV ADVVSLRTGI PVNKLTETDR QRLLSLPASL QAQVIGQEEA
VEAVANAIIR SRAGLARRNA PIGTFLFLGS TGVGKTELAK ALTAAIFHDE KNLIRLDMSE
YSEPHTVARL VGSPPGYVSH DEGGQLTEAV RQRPHSVVLF DEIENAHPNV FAYLLQLLDE
GRLTDMRGIT VDFTNCVIIA TSNIGAKHIL AASEKAGDEA SGKVTIGHFD SERQQLEHIA
DANAGAQVAE EVNGDKKDST SPAQEKALAR KKVANWKTQA RAAVLAEAAR VFKPQVLNRM
TVIIFDPLTP QDLKRIFRLQ QKGLADLLSE QRIDLVVEED AVTFVVERAY SRHFGARRLK
RFFDKNITGR LAPWILSGWL RSGMMLRIIV SKTRKNSLEA HICDVNSRGR CIKASRRARL
LCTVKVPDPT KDAEDPL
//
