ID V4ZHB4_TOXGV Unreviewed; 605 AA.
AC V4ZHB4; A0A0F7UUI9;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Glycosyltransferase sugar-binding region containing DXD motif protein {ECO:0000313|EMBL:ESS33256.1};
GN ORFNames=BN1205_044440 {ECO:0000313|EMBL:CEL73706.1}, TGVEG_205060
GN {ECO:0000313|EMBL:ESS33256.1};
OS Toxoplasma gondii (strain ATCC 50861 / VEG).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Sarcocystidae; Toxoplasma.
OX NCBI_TaxID=432359 {ECO:0000313|EMBL:ESS33256.1, ECO:0000313|Proteomes:UP000002226};
RN [1] {ECO:0000313|EMBL:ESS33256.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VEG {ECO:0000313|EMBL:ESS33256.1};
RA Paulsen I.;
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50861 / VEG {ECO:0000313|Proteomes:UP000002226};
RA Lorenzi H., Inman J., Amedeo P., Brunk B., Roos D., Caler E.;
RT "Annotation of Toxoplasma gondii VEG.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ESS33256.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VEG {ECO:0000313|EMBL:ESS33256.1};
RA Sibley D., Venepally P., Karamycheva S., Hadjithomas M., Khan A., Brunk B.,
RA Roos D., Caler E., Lorenzi H.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:CEL73706.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VEG {ECO:0000313|EMBL:CEL73706.1};
RX PubMed=25875305; DOI=10.1371/journal.pone.0124473;
RA Ramaprasad A., Mourier T., Naeem R., Malas T.B., Moussa E., Panigrahi A.,
RA Vermont S.J., Otto T.D., Wastling J., Pain A.;
RT "Comprehensive Evaluation of Toxoplasma gondii VEG and Neospora caninum LIV
RT Genomes with Tachyzoite Stage Transcriptome and Proteome Defines Novel
RT Transcript Features.";
RL PLoS ONE 10:e0124473-e0124473(2015).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LN714496; CEL73706.1; -; Genomic_DNA.
DR EMBL; AAYL02000111; ESS33256.1; -; Genomic_DNA.
DR AlphaFoldDB; V4ZHB4; -.
DR STRING; 432359.V4ZHB4; -.
DR PaxDb; 5811-TGME49_005060; -.
DR EnsemblProtists; ESS33256; ESS33256; TGVEG_205060.
DR VEuPathDB; ToxoDB:TGVEG_205060; -.
DR eggNOG; ENOG502QZYI; Eukaryota.
DR OMA; LATTCIC; -.
DR Proteomes; UP000002226; Partially assembled WGS sequence.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006688; P:glycosphingolipid biosynthetic process; IEA:UniProt.
DR GO; GO:0006673; P:inositol phosphoceramide metabolic process; IEA:UniProt.
DR Gene3D; 3.90.550.20; -; 1.
DR InterPro; IPR007577; GlycoTrfase_DXD_sugar-bd_CS.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR32385; MANNOSYL PHOSPHORYLINOSITOL CERAMIDE SYNTHASE; 1.
DR PANTHER; PTHR32385:SF15; MANNOSYL PHOSPHORYLINOSITOL CERAMIDE SYNTHASE CSH1-RELATED; 1.
DR Pfam; PF04488; Gly_transf_sug; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002226};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT REGION 494..537
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 496..513
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 605 AA; 67627 MW; 70D3F30F85676B29 CRC64;
MRESLGDCSV DCLSSCEKHG NMRSLDARGR LAETTYRQNR IDFPDFPSHS VIQFNLWSSE
DNTWLSLLRG LWHRCNARRV LLAASGDPRE PAHLSEEVTS KRHRLPGVAT PRLNCDSELL
KCYKNGGDLK GVDHHCPQPA PADSRGDRDG EAFCADRALS ASLAQAIREA KLYCGHPERT
VVDCRSSCCL EETGRHTPPE LPLVDGGHSS AGCKNFSSAF MKIPSEFVSG KAIPPLLHFV
WLGGHPPPFF ETIRQSWAVH NPDLIQALWT DAHVESLLDV LDRKSRSRRP KCRKTDHQDL
HPLLVDRPAT DAGETTEWEM SDSVSDSQTL VHAIKAFRKE SCPAAKSDIA RLLLLCHYGG
IYADVDMEAI KPLPPCLRQC TTVFMGMQRP DAVELGNALI GCSSGHELIR FILQRVGRPY
SQWGTRSTDQ MAVVLDILKL HVARFSPEAS ELMDSLRSTN DEATNVIERT GPGLLTRATL
AWLRDQLNSS SCARCRPQER RSHDYEHKSN TTEATSVHAD VVGSETGSKE DDSKPEATSG
TCCCILATTC ICPPIFFYPV PNHRRKELRE GKVQTEHLES SFSYTVHHWR QTWQDSVRQE
SENEC
//
