ID   V5A4J1_TRYCR            Unreviewed;       315 AA.
AC   V5A4J1;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=Trans-sialidase {ECO:0000313|EMBL:ESS55670.1};
GN   ORFNames=TCDM_12843 {ECO:0000313|EMBL:ESS55670.1};
OS   Trypanosoma cruzi Dm28c.
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX   NCBI_TaxID=1416333 {ECO:0000313|EMBL:ESS55670.1, ECO:0000313|Proteomes:UP000017861};
RN   [1] {ECO:0000313|EMBL:ESS55670.1, ECO:0000313|Proteomes:UP000017861}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Dm28c {ECO:0000313|EMBL:ESS55670.1,
RC   ECO:0000313|Proteomes:UP000017861};
RX   PubMed=24482508;
RA   Grisard E.C., Teixeira S.M., de Almeida L.G., Stoco P.H., Gerber A.L.,
RA   Talavera-Lopez C., Lima O.C., Andersson B., de Vasconcelos A.T.;
RT   "Trypanosoma cruzi Clone Dm28c Draft Genome Sequence.";
RL   Genome Announc. 2:e01114-13(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ESS55670.1}.
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DR   EMBL; AYLP01000719; ESS55670.1; -; Genomic_DNA.
DR   AlphaFoldDB; V5A4J1; -.
DR   EnsemblProtists; ESS55670; ESS55670; TCDM_12843.
DR   VEuPathDB; TriTrypDB:TCDM_12843; -.
DR   Proteomes; UP000017861; Unassembled WGS sequence.
DR   CDD; cd15482; Sialidase_non-viral; 1.
DR   Gene3D; 2.120.10.10; -; 1.
DR   InterPro; IPR011040; Sialidase.
DR   InterPro; IPR036278; Sialidase_sf.
DR   Pfam; PF13859; BNR_3; 1.
DR   SUPFAM; SSF50939; Sialidases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000017861}.
FT   DOMAIN          90..305
FT                   /note="Sialidase"
FT                   /evidence="ECO:0000259|Pfam:PF13859"
FT   REGION          1..39
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        24..38
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   315 AA;  34270 MW;  09A346FDBBECDEA6 CRC64;
     MLSRVAAVKA PRTHNRRRVT GSRGRRREGR ESEPQRPNMS RHHFCSAVLL LVLVMMCGSG
     GAAQDPRQSS ERNYKWKVIP EGETVESLGA PGLLKVGSDV FAVAEAQCKK SDVIFTGMAS
     QLLTIDNPDK PVEVLNGAED KTQVLEEDGS EDPKKKLDVS RPTTVMKGND IYMLVGKYSR
     TDATDQEDGG ADDGGLLLVK GKVCDEVASG KRIQWKDNDG VSRISVGERE SWSRLTGSGG
     SGIETEDGTL VFPVEAVKKG DAVKDKRAVS LIIYTLKDTD EVWKLSKGIP DGGCSDPSVV
     EWGEKDKKTH HDDCV
//