ID V5AB77_9ARCH Unreviewed; 183 AA.
AC V5AB77;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=sulfopyruvate decarboxylase {ECO:0000256|ARBA:ARBA00038875};
DE EC=4.1.1.79 {ECO:0000256|ARBA:ARBA00038875};
GN ORFNames=A07HR60_00216 {ECO:0000313|EMBL:ESS12980.1};
OS uncultured archaeon A07HR60.
OC Archaea; environmental samples.
OX NCBI_TaxID=1412874 {ECO:0000313|EMBL:ESS12980.1, ECO:0000313|Proteomes:UP000030679};
RN [1] {ECO:0000313|Proteomes:UP000030679}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24335829;
RA Podell S., Emerson J.B., Jones C.M., Ugalde J.A., Welch S.,
RA Heidelberg K.B., Banfield J.F., Allen E.E.;
RT "Seasonal fluctuations in ionic concentrations drive microbial succession
RT in a hypersaline lake community.";
RL ISME J. 0:0-0(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3-sulfopyruvate + H(+) = CO2 + sulfoacetaldehyde;
CC Xref=Rhea:RHEA:20948, ChEBI:CHEBI:15378, ChEBI:CHEBI:16526,
CC ChEBI:CHEBI:57940, ChEBI:CHEBI:58246; EC=4.1.1.79;
CC Evidence={ECO:0000256|ARBA:ARBA00036439};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KI543223; ESS12980.1; -; Genomic_DNA.
DR AlphaFoldDB; V5AB77; -.
DR STRING; 1412874.A07HR60_00216; -.
DR Proteomes; UP000030679; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR GO; GO:0006082; P:organic acid metabolic process; IEA:UniProt.
DR GO; GO:1901576; P:organic substance biosynthetic process; IEA:UniProt.
DR GO; GO:0044272; P:sulfur compound biosynthetic process; IEA:UniProt.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR011766; TPP_enzyme_TPP-bd.
DR PANTHER; PTHR42818:SF1; SULFOPYRUVATE DECARBOXYLASE; 1.
DR PANTHER; PTHR42818; SULFOPYRUVATE DECARBOXYLASE SUBUNIT ALPHA; 1.
DR Pfam; PF02775; TPP_enzyme_C; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
PE 4: Predicted;
KW Coenzyme M biosynthesis {ECO:0000256|ARBA:ARBA00022545};
KW Reference proteome {ECO:0000313|Proteomes:UP000030679}.
FT DOMAIN 42..154
FT /note="Thiamine pyrophosphate enzyme TPP-binding"
FT /evidence="ECO:0000259|Pfam:PF02775"
SQ SEQUENCE 183 AA; 18901 MW; 228C2B5FE0475198 CRC64;
MPADQAACTA AVLEETPDAV VISNLGVASY VLSGVADRSR NFYLWGSMGS TTATGIGVAY
GTDEQVTVLD GDGSLTMSLG VLATVANADV PNLTVVCFDN GTYGTTGGQP TPSIEFAAAA
EACGLPANSV ETTNGFTEAY SAASNRETAS VIECDVTPVD PDSRPMFDFS HITRRVRDAL
TEE
//
