ID V5AI84_TRYCR Unreviewed; 390 AA.
AC V5AI84;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 22-FEB-2023, entry version 23.
DE SubName: Full=Glycoprotein 82 kDa {ECO:0000313|EMBL:ESS60330.1};
GN ORFNames=TCDM_12146 {ECO:0000313|EMBL:ESS60330.1};
OS Trypanosoma cruzi Dm28c.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=1416333 {ECO:0000313|EMBL:ESS60330.1, ECO:0000313|Proteomes:UP000017861};
RN [1] {ECO:0000313|EMBL:ESS60330.1, ECO:0000313|Proteomes:UP000017861}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Dm28c {ECO:0000313|EMBL:ESS60330.1,
RC ECO:0000313|Proteomes:UP000017861};
RX PubMed=24482508;
RA Grisard E.C., Teixeira S.M., de Almeida L.G., Stoco P.H., Gerber A.L.,
RA Talavera-Lopez C., Lima O.C., Andersson B., de Vasconcelos A.T.;
RT "Trypanosoma cruzi Clone Dm28c Draft Genome Sequence.";
RL Genome Announc. 2:e01114-13(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESS60330.1}.
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DR EMBL; AYLP01000498; ESS60330.1; -; Genomic_DNA.
DR AlphaFoldDB; V5AI84; -.
DR EnsemblProtists; ESS60330; ESS60330; TCDM_12146.
DR VEuPathDB; TriTrypDB:TCDM_12146; -.
DR Proteomes; UP000017861; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR CDD; cd15482; Sialidase_non-viral; 1.
DR Gene3D; 2.120.10.10; -; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR011040; Sialidase.
DR InterPro; IPR036278; Sialidase_sf.
DR InterPro; IPR008377; Sialidase_trypan.
DR InterPro; IPR021287; Trans-sialidase_CS.
DR Pfam; PF13859; BNR_3; 1.
DR Pfam; PF11052; Tr-sialidase_C; 1.
DR PRINTS; PR01803; TCSIALIDASE.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF50939; Sialidases; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000017861};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 371..389
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..125
FT /note="Sialidase"
FT /evidence="ECO:0000259|Pfam:PF13859"
SQ SEQUENCE 390 AA; 43072 MW; 8D3C04924D18F6F4 CRC64;
MIVDCENEQN VYESRDMGTT WTEAIGTLPG VWTKSKPEVS RDVSLHVEAL ITANIEGRKV
MLYTQRGYAL REKRATALYL WVTDNNRSFY FGPVAVEEAV KWEFASALLY SDGKLHLLQR
RDNNKGGVIS LSRMTEELST IRSVLSTWSQ KDVFFSRFSI PTAGLVAVLS DAAGDDTWND
EYLCLNATVT NAKKVKDGFQ LTEPDSGVMW PVNTQGNNVR HVVLSHDFTL VASVTIEVAP
SNNTPLLGAT LGDTNSSHTM GILYTADNKW GTIFNDKITK SGTWEPGKEY QVALMLQGNK
SFVYIDGKLL GEEETMLTGK TPLELAGFCF GACELHNSPV TVKNVFLYNR PLGAGELRMV
KKSDGSMHGG VSRALLLLML LGMWGIAALY
//
