ID V5BBL5_TRYCR Unreviewed; 593 AA.
AC V5BBL5;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 22-FEB-2023, entry version 26.
DE SubName: Full=Trans-sialidase {ECO:0000313|EMBL:ESS61783.1};
GN ORFNames=TCDM_10611 {ECO:0000313|EMBL:ESS61783.1};
OS Trypanosoma cruzi Dm28c.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=1416333 {ECO:0000313|EMBL:ESS61783.1, ECO:0000313|Proteomes:UP000017861};
RN [1] {ECO:0000313|EMBL:ESS61783.1, ECO:0000313|Proteomes:UP000017861}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Dm28c {ECO:0000313|EMBL:ESS61783.1,
RC ECO:0000313|Proteomes:UP000017861};
RX PubMed=24482508;
RA Grisard E.C., Teixeira S.M., de Almeida L.G., Stoco P.H., Gerber A.L.,
RA Talavera-Lopez C., Lima O.C., Andersson B., de Vasconcelos A.T.;
RT "Trypanosoma cruzi Clone Dm28c Draft Genome Sequence.";
RL Genome Announc. 2:e01114-13(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESS61783.1}.
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DR EMBL; AYLP01000243; ESS61783.1; -; Genomic_DNA.
DR AlphaFoldDB; V5BBL5; -.
DR EnsemblProtists; ESS61783; ESS61783; TCDM_10611.
DR VEuPathDB; TriTrypDB:TCDM_10611; -.
DR Proteomes; UP000017861; Unassembled WGS sequence.
DR GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR CDD; cd15482; Sialidase_non-viral; 1.
DR Gene3D; 2.120.10.10; -; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR011040; Sialidase.
DR InterPro; IPR036278; Sialidase_sf.
DR InterPro; IPR008377; Sialidase_trypan.
DR InterPro; IPR021287; Trans-sialidase_CS.
DR Pfam; PF13859; BNR_3; 1.
DR Pfam; PF13385; Laminin_G_3; 1.
DR Pfam; PF11052; Tr-sialidase_C; 1.
DR PRINTS; PR01803; TCSIALIDASE.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF50939; Sialidases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000017861}.
FT DOMAIN 1..150
FT /note="Sialidase"
FT /evidence="ECO:0000259|Pfam:PF13859"
FT REGION 431..459
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 479..572
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 443..459
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 491..505
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 550..572
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 593 AA; 62449 MW; E5E78F3880DB0227 CRC64;
MSADGCGDPS VVEWKDDKLM MMTACDGGRR RVYESGDKGE SWTEALGTLS RVWGNDKKGK
VKIVRSGFIT AALGDNEGNN RNVMLVTLPV YSKEEDNSKG VLHLWLTDNT HIVDIGSVSG
DDVDAAASSL LYKSGESGDS NDEKLIALYE KKKGAGEKPS PGMVSVLLTE QLKRVREVLT
TWKEVDERVS KLCPLSSAAK DDSTATACST TFKITDGLVG FLSGNFSDTT WKDEYLGVNA
TVNNKAAAEK TDNGVKFTGR GAWTEWPVGS QGENQLYHFA NYNFTLVATV SIDKVPEEVT
SISVMGAKLN DGGKTVLFGL SYNDNEKKWI LLCGGGENKK YSSDWETKTS EHVVVLLRNG
NQSSAYVDGQ PVGGDEQCEL KTKASKEISH FYIGGDGGSA EGQEGVSVTV SNVLLYNRPL
SSEEIAGLAK NKVTIPEPEG PKTSIDTRSS AVSGSPVQGA VSLSNSARQL PLEQELLKEN
IGGGGGGVSG AASVTTPSAD ANTPASNGEG KVEPAVKEEM SASSGEDEDT ADGTDAQGEE
GIHPPAGEVN ATALSSSPGN VSQGNNSDDD TMSGSGLLPS LLLLLGLWVF AAL
//
