ID   V5BDF2_TRYCR            Unreviewed;       521 AA.
AC   V5BDF2;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   RecName: Full=tRNA-specific 2-thiouridylase MnmA-like C-terminal domain-containing protein {ECO:0000259|Pfam:PF20258};
GN   ORFNames=TCDM_07989 {ECO:0000313|EMBL:ESS64032.1};
OS   Trypanosoma cruzi Dm28c.
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX   NCBI_TaxID=1416333 {ECO:0000313|EMBL:ESS64032.1, ECO:0000313|Proteomes:UP000017861};
RN   [1] {ECO:0000313|EMBL:ESS64032.1, ECO:0000313|Proteomes:UP000017861}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Dm28c {ECO:0000313|EMBL:ESS64032.1,
RC   ECO:0000313|Proteomes:UP000017861};
RX   PubMed=24482508;
RA   Grisard E.C., Teixeira S.M., de Almeida L.G., Stoco P.H., Gerber A.L.,
RA   Talavera-Lopez C., Lima O.C., Andersson B., de Vasconcelos A.T.;
RT   "Trypanosoma cruzi Clone Dm28c Draft Genome Sequence.";
RL   Genome Announc. 2:e01114-13(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ESS64032.1}.
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DR   EMBL; AYLP01000103; ESS64032.1; -; Genomic_DNA.
DR   AlphaFoldDB; V5BDF2; -.
DR   EnsemblProtists; ESS64032; ESS64032; TCDM_07989.
DR   VEuPathDB; TriTrypDB:TCDM_07989; -.
DR   Proteomes; UP000017861; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.620; HUPs; 1.
DR   Gene3D; 2.40.30.10; Translation factors; 1.
DR   InterPro; IPR046885; MnmA-like_C.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   PANTHER; PTHR11933:SF5; MITOCHONDRIAL TRNA-SPECIFIC 2-THIOURIDYLASE 1; 1.
DR   PANTHER; PTHR11933; TRNA 5-METHYLAMINOMETHYL-2-THIOURIDYLATE -METHYLTRANSFERASE; 1.
DR   Pfam; PF03054; tRNA_Me_trans; 1.
DR   Pfam; PF20258; tRNA_Me_trans_C; 1.
DR   SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000017861}.
FT   DOMAIN          429..498
FT                   /note="tRNA-specific 2-thiouridylase MnmA-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF20258"
SQ   SEQUENCE   521 AA;  57501 MW;  DBB3034A8A60E2AA CRC64;
     MSCTVVRVAI ALSGGVDSAV AALFLRRCVP HWGDVEALWR LERPLALCEV VEALEQQRPL
     SEVVALAPAT GNSHDPAAAV KYFPLFMKNW DDAFESDGVG QSWCEAAQQE YNDATDVARA
     LGLLHSREIL PFHNYSACYV EKCFQPMLDA YARGATLNVD VLCNEEVKFL ALLDALLTAG
     RAAYLATGHY ARTVHFPLLS CENAAPTALR VIARPFSARN DLNDQTVFLS RLSKRQTLRA
     IFPLGHVFER KSDVRAVAEH FGMKRISTKK TSTGLCFVGE HYRRAGRGGS CAGGFRSFLE
     EYMAPNCTAL QKLTAAGQQT TFINAENGDV VEASGLALHG DDDGVLLPAY SLTIGQLIRG
     KSEDGKMVRY YVQGKKLFSF RENCNKGDNE DDDGGYVRHL HTVWLVDRWD HPLLYGKVAK
     IYDVKLSVHP QWLGNREGSV RLHCRCCARH QEPLRPALLS FDWSDVSEKD VCIRVATATV
     LFEEPVRALT PGQALVAYIS LSKEGAEDAA GWFVVASGWI A
//