ID V5BHI7_TRYCR Unreviewed; 797 AA.
AC V5BHI7;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Phospholipid-transporting ATPase 1-like protein {ECO:0000313|EMBL:ESS67204.1};
GN ORFNames=TCDM_04122 {ECO:0000313|EMBL:ESS67204.1};
OS Trypanosoma cruzi Dm28c.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=1416333 {ECO:0000313|EMBL:ESS67204.1, ECO:0000313|Proteomes:UP000017861};
RN [1] {ECO:0000313|EMBL:ESS67204.1, ECO:0000313|Proteomes:UP000017861}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Dm28c {ECO:0000313|EMBL:ESS67204.1,
RC ECO:0000313|Proteomes:UP000017861};
RX PubMed=24482508;
RA Grisard E.C., Teixeira S.M., de Almeida L.G., Stoco P.H., Gerber A.L.,
RA Talavera-Lopez C., Lima O.C., Andersson B., de Vasconcelos A.T.;
RT "Trypanosoma cruzi Clone Dm28c Draft Genome Sequence.";
RL Genome Announc. 2:e01114-13(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESS67204.1}.
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DR EMBL; AYLP01000034; ESS67204.1; -; Genomic_DNA.
DR AlphaFoldDB; V5BHI7; -.
DR EnsemblProtists; ESS67204; ESS67204; TCDM_04122.
DR VEuPathDB; TriTrypDB:TCDM_04122; -.
DR Proteomes; UP000017861; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR032631; P-type_ATPase_N.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR PANTHER; PTHR24092:SF150; PHOSPHOLIPID-TRANSPORTING ATPASE; 1.
DR PANTHER; PTHR24092; PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE; 1.
DR Pfam; PF13246; Cation_ATPase; 1.
DR Pfam; PF16209; PhoLip_ATPase_N; 1.
DR SFLD; SFLDS00003; Haloacid_Dehalogenase; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF81660; Metal cation-transporting ATPase, ATP-binding domain N; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
DR PROSITE; PS50889; S4; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000017861};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00182};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 75..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 291..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 334..363
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 32..98
FT /note="P-type ATPase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16209"
SQ SEQUENCE 797 AA; 90529 MW; B2F3A0CC1E1D3AA1 CRC64;
MVYGKVRGCA WCSGCKREED ELDDDEQLEV VVHMNDRKAN APYNYPDNFI RTTQYTLLTF
LPLGLLMQFR KVSNFYFLVC MILALIPGVS PISPATAIAP LVFVIGVAMV KEAVEEFKRH
RADRKANSIL VDVLVNGKLE KVASRDLRAG DIVRVHNGEE VRADIFYLSS HTEEGQVFID
TCNLDGETSL KGRKSIEVTR SLCSPEGLNA AQITMYTVPP EPGLLAWTGR IEIDGKDYAV
DINQFLYRGC ILRKTDWLWG FVIYAGVDTK MFRNLRKRPP KSSDLDLKLN ILIIIVFLLQ
NVFLFLLCSL SVWWNGRHKN HWYIRWYLES HGKAAQWFLS YLTYFVLLSY LIPISLFVTI
ELCKVIQAYW IRRDNKMKEM VNGRWRHCKP NTSNLNEQLA MVRYIFTDKT GTLTENAMKF
KMGDIKGHLI YNENHSFSLE LLQRQGVIRT AAEEYFLALA ICHTIQPFPD ADAPLGVVYE
GGSPDEVALV TTAAEHGFRL LERNSRCLTV EVEGERRVYD ILATLEFTPE RKMMSIIVQE
RNTERIILFT KGADSSVGSR TADEEDVQEY MQILSQSLLD MAEHGLRTLL IATRDLTSEM
FSEWNTRFLA AGKVLVRRNE AVDRLCGEIE QELRLLGATA IEDKLQEEVP ETVSFFREAG
VMMWMLTGDK RETAVTIAAT SSLLDPRRDY VVHVDLGSLD PKDPEAIEKI GADLHQVELH
LESGRREGVR CTLVIDGTSL GVVMEHYFEL FVRLSKCVSS AVCCRLTPLQ KAEIVRMFQK
STGFTALAIG DGANDVP
//
