ID V5BHQ4_TRYCR Unreviewed; 409 AA.
AC V5BHQ4;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Translation initiation factor eIF2B subunit delta {ECO:0000256|ARBA:ARBA00044147};
DE AltName: Full=eIF2B GDP-GTP exchange factor subunit delta {ECO:0000256|ARBA:ARBA00044356};
GN ORFNames=TCDM_08044 {ECO:0000313|EMBL:ESS64013.1};
OS Trypanosoma cruzi Dm28c.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=1416333 {ECO:0000313|EMBL:ESS64013.1, ECO:0000313|Proteomes:UP000017861};
RN [1] {ECO:0000313|EMBL:ESS64013.1, ECO:0000313|Proteomes:UP000017861}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Dm28c {ECO:0000313|EMBL:ESS64013.1,
RC ECO:0000313|Proteomes:UP000017861};
RX PubMed=24482508;
RA Grisard E.C., Teixeira S.M., de Almeida L.G., Stoco P.H., Gerber A.L.,
RA Talavera-Lopez C., Lima O.C., Andersson B., de Vasconcelos A.T.;
RT "Trypanosoma cruzi Clone Dm28c Draft Genome Sequence.";
RL Genome Announc. 2:e01114-13(2014).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}.
CC -!- SIMILARITY: Belongs to the eIF-2B alpha/beta/delta subunits family.
CC {ECO:0000256|ARBA:ARBA00007251, ECO:0000256|RuleBase:RU003814}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESS64013.1}.
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DR EMBL; AYLP01000104; ESS64013.1; -; Genomic_DNA.
DR AlphaFoldDB; V5BHQ4; -.
DR EnsemblProtists; ESS64013; ESS64013; TCDM_08044.
DR VEuPathDB; TriTrypDB:TCDM_08044; -.
DR Proteomes; UP000017861; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR InterPro; IPR000649; IF-2B-related.
DR InterPro; IPR042529; IF_2B-like_C.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR PANTHER; PTHR10233; TRANSLATION INITIATION FACTOR EIF-2B; 1.
DR PANTHER; PTHR10233:SF14; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT DELTA; 1.
DR Pfam; PF01008; IF-2B; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540,
KW ECO:0000313|EMBL:ESS64013.1};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000017861}.
FT REGION 324..358
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 338..358
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 409 AA; 44414 MW; EE8D4F835E68D1C7 CRC64;
MPFQPPCSSE LVHYQVAELA LMMESMVIVG GNARTLAMIQ AFKSLLQTTP VLSGPSLRDV
NSKVFEELID ENFNFLRRGR EPSTGMTYVK EVLVRRVAAL LSSGGDFRVS EDGSFIPLEK
EKKQGALEVT ESPLTLSSDV ENSLLAGDPR EVSLKVLAGI EKELRLSIKS IVEDRSIPLI
SSNDTIMVFG RSSTVELILL GAANNPRLGV KPRVIVVDAA PLYEGRALAK RLTTSGLSVT
YGLITSCCTL MPHCTRVFIG AAAVLQNGDV FSRCGTAVVV ASAKQYRKPV LCFSESFKFI
SEVWLGNLGQ NTQLQFSQSL PGDHRIRSPG GMSPPRHQNR EINEQPFGRS NDGLPMQSSA
SSASGYLYDL TPAAFIDMII CEMGCLDTSA IVAALRDRED RDACLMSVA
//
